Search Results - "Mahvash, A."

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    Long Short-Term Memory Neural Networks for Modeling Nonlinear Electronic Components by Moradi A., Mahvash, Sadrossadat, Sayed Alireza, Derhami, Vali

    “…This article presents a new macromodeling approach for nonlinear electronic components and circuits based on long short-term memory (LSTM) neural network. LSTM…”
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    Journal Article
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    Cell Surface Calcium‐Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca2+ Sensing but Not G Protein Interaction by Goolam, Mahvash A., Brown, Alice P., Edwards, Kimberly T., Gregory, Karen J., Leach, Katie, Conigrave, Arthur D.

    Published in Journal of bone and mineral research (01-09-2022)
    “…ABSTRACT The calcium‐sensing receptor is a homodimeric class C G protein‐coupled receptor (GPCR) that senses extracellular Ca2+ (Ca2+o) via a dimeric…”
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    Atezolizumab plus bevacizumab in advanced Merkel cell carcinoma: A prospective study by de Sousa, L. Guimaraes, Liu, S., Bhosale, P., Altan, M., Darbonne, W., Schulze, K., Dervin, S., Yun, C., Mahvash, A., Verma, A., Futreal, A., Gite, S., Cuentas, E. Parra, Cho, W.C., Wistuba, I., Yao, J.C., Woodman, S.E., Halperin, D.M., Ferrarotto, R.

    Published in Oral oncology (01-04-2024)
    “…•In this phase II trial of atezolizumab and bevacizumab in advanced MCC patients, the ORR was 64 %, with 27 % complete responses.•Atezolizumab and bevacizumab…”
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    Roles of intraloops-2 and -3 and the proximal C-terminus in signalling pathway selection from the human calcium-sensing receptor by Goolam, Mahvash A., Ward, James H., Avlani, Vimesh A., Leach, Katie, Christopoulos, Arthur, Conigrave, Arthur D.

    Published in FEBS letters (17-09-2014)
    “…•Intracellular loops-2 (iL-2) and -3 (iL-3) and the proximal C-terminus support Ca2+o-stimulated signalling.•The proximal C-terminus is not required for…”
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    Mechanisms of multimodal sensing by extracellular Ca(2+)-sensing receptors: a domain-based survey of requirements for binding and signalling by Khan, Mahvash A, Conigrave, Arthur D

    Published in British journal of pharmacology (01-03-2010)
    “…In this article we consider the molecular basis of sensing and signalling by the extracellular calcium-sensing receptor. We consider the nature of its ligands…”
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    Mechanisms of multimodal sensing by extracellular Ca2+‐sensing receptors: a domain‐based survey of requirements for binding and signalling by Khan, Mahvash A, Conigrave, Arthur D

    Published in British journal of pharmacology (01-03-2010)
    “…In this article we consider the molecular basis of sensing and signalling by the extracellular calcium‐sensing receptor. We consider the nature of its ligands…”
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    Radioembolization with 90Y Resin Microspheres of Neuroendocrine Liver Metastases After Initial Peptide Receptor Radionuclide Therapy by Braat, A. J. A. T., Ahmadzadehfar, H., Kappadath, S. C., Stothers, C. L., Frilling, A., Deroose, C. M., Flamen, P., Brown, D. B., Sze, D. Y., Mahvash, A., Lam, M. G. E. H.

    “…Purpose Peptide receptor radionuclide therapy (PRRT) and radioembolization are increasingly used in neuroendocrine neoplasms patients. However, concerns have…”
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    Radioembolization with 90Y Resin Microspheres of Neuroendocrine Liver Metastases: International Multicenter Study on Efficacy and Toxicity by Braat, A. J. A. T., Kappadath, S. C., Ahmadzadehfar, H., Stothers, C. L., Frilling, A., Deroose, C. M., Flamen, P., Brown, D. B., Sze, D. Y., Mahvash, A., Lam, M. G. E. H.

    “…Purpose Radioembolization of liver metastases of neuroendocrine neoplasms (NEN) has shown promising results; however, the current literature is of limited…”
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    Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism by Gregory, Karen J, Kufareva, Irina, Keller, Andrew N, Khajehali, Elham, Mun, Hee-Chang, Goolam, Mahvash A, Mason, Rebecca S, Capuano, Ben, Conigrave, Arthur D, Christopoulos, Arthur, Leach, Katie

    Published in ACS pharmacology & translational science (09-11-2018)
    “…Negative allosteric modulators (NAMs) of the human calcium-sensing receptor (CaSR) have previously failed to show efficacy in human osteoporosis clinical…”
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    Yttirum-90 resin microspheres as an adjunct to sorafenib in patients with unresectable HCC: a retrospective study for evaluation of survival benefit and adverse events by Gadani, S, Mahvash, A, Avritscher, R, Chasen, B, Kaseb, A, Murthy, R

    “…Purpose Efficacy and safety of sorafenib (Nexavar®, Bayer Pharmaceuticals, Germany) in the treatment of advanced HCC has been well established. The efficacy…”
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    KRAS mutant metastatic colorectal cancer;is there a role for Yttrium-90 microsphere radioembolotherapy? by Odisio, B.C, Shreyaah, S, Mahvash, A, Avritscher, R, Chasen, B, Murthy, R, Garrett, C

    “…Purpose Yttrium-90 microsphere radioembolotherapy (Y90mRE) and EGFR receptor inhibitors (cetuximab, panitumumab) have been utilized predominantly in…”
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