Search Results - "Mahungu, T W"

The impact of pharmacogenetics on HIV therapy by Mahungu, T W, Johnson, M A, Owen, A, Back, D J

“…The use of highly active antiretroviral therapy in the treatment of HIV infection has resulted in significant reductions in mortality and morbidity worldwide…”
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The Relationships of ABCB1 3435C>T and CYP2B6 516G>T With High-Density Lipoprotein Cholesterol in HIV-Infected Patients Receiving Efavirenz by Mahungu, TW, Nair, D, Smith, CJ, Egan, D, Youle, M, Johnson, MA, Khoo, SH, Back, DJ, Owen, A

“…Non‐nucleoside reverse transcriptase inhibitors (NNRTIs) are associated with a favorable increase in high‐density lipoprotein cholesterol (HDL‐c) level…”
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Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population by Mahungu, TW, Smith, CJ, Turner, F, Egan, D, Youle, M, Johnson, MA, Khoo, S, Back, DJ, Owen, A

“…Objectives The aim of the study was to characterize the impact of the cytochrome P450 2B6 (CYP2B6), CYP3A4, CYP3A5 and ATP‐binding cassette sub‐family B member…”
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The Relationships of ABCB1 3435C>T and CYP2B6 516G>TWith High-Density Lipoprotein Cholesterol in HIV-Infected Patients Receiving Efavirenz by MAHUNGU, T. W, NAIR, D, SMITH, C. J, EGAN, D, YOULE, M, JOHNSON, M. A, KHOO, S. H, BACK, D. J, OWEN, A

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Cytochrome P450 2B6 516G1T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population by Mahungu, T W, Smith, C J, Turner, F, Egan, D, Youle, M, Johnson, MA, Khoo, S, Back, D J, Owen, A

“…ObjectivesThe aim of the study was to characterize the impact of the cytochrome P450 2B6 (CYP2B6), CYP3A4, CYP3A5 and ATP-binding cassette sub-family B member…”
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A study to evaluate the efficacy, safety and tolerability of co-administered lopinavir/ritonavir (LPVr) and nevirapine (NVP) in HIV-infected adults by Mahungu, TW, Else, LJ, Smith, CJ, Cuthbertson, Z, Podlekareva, D, Hay, P, Dragsted, UB, Khoo, SH, Johnson, MA, Back, DJ, Youle, M

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An open-label multicentre pilot study evaluating the pharmacokinetics (PK) of co-administered lopinavir (LPV) and nevirapine (NVP) in HIV+ adults by Else, LJ, Mahungu, TW, Cuthbertson, Z, Smith, CJ, Podlekareva, D, Hay, P, Dragsted, UB, Khoo, SH, Johnson, MA, Back, DJ, Youle, M

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