Search Results - "Mahnashi, Mater H"
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Simultaneous electrochemical detection of azithromycin and hydroxychloroquine based on VS2 QDs embedded N, S @graphene aerogel/cCNTs 3D nanostructure
Published in Microchemical journal (01-04-2021)“…•Electrochemical sensor was proposed for analysis of AZM and HCQ.•The electrochemical sensor is VS2-QDs/GNA/cCNTs.•The sensor exhibits good sensitivity,…”
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2
Plant-Based Synthesis of Gold Nanoparticles and Theranostic Applications: A Review
Published in Molecules (Basel, Switzerland) (18-02-2022)“…Bionanotechnology is a branch of science that has revolutionized modern science and technology. Nanomaterials, especially noble metals, have attracted…”
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3
Design, synthesis and bioevaluation of new vanillin hybrid as multitarget inhibitor of α-glucosidase, α-amylase, PTP-1B and DPP4 for the treatment of type-II diabetes
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Diabetes mellitus (DM) is a real challenge to the recent era and is one of the major diseases for initiating life-threatening disorders. In current research, a…”
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4
3-(((1 S ,3 S )-3-(( R )-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target Antidiabetic Agent
Published in Molecules (Basel, Switzerland) (19-05-2022)“…The chiral drug candidates have more effective binding affinities for their specific protein or receptor site for the onset of pharmacological action…”
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5
Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic Acids through In Vitro, In Silico and In Vivo Studies
Published in Molecules (Basel, Switzerland) (24-06-2022)“…In the current study, a series of new (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals (FM1-6) with their corresponding carboxylic acid…”
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Bacillus subtilis: As an Efficient Bacterial Strain for the Reclamation of Water Loaded with Textile Azo Dye, Orange II
Published in International journal of molecular sciences (13-09-2022)“…The azo dye orange II is used extensively in the textile sector for coloring fabrics. High concentrations of it are released into aqueous environments through…”
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Label-Free Electrochemical Sensor Based on Manganese Doped Titanium Dioxide Nanoparticles for Myoglobin Detection: Biomarker for Acute Myocardial Infarction
Published in Molecules (Basel, Switzerland) (13-07-2021)“…A label free electrochemical sensor based on pure titanium oxide and manganese (Mn)-doped titanium oxide (TiO ) nanoparticles are fabricated and characterized…”
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Synthesis and Characterization of Silver Nanoparticles from Rhizophora apiculata and Studies on Their Wound Healing, Antioxidant, Anti-Inflammatory, and Cytotoxic Activity
Published in Molecules (Basel, Switzerland) (24-09-2022)“…Silver nanoparticles (AgNPs) have recently gained interest in the medical field because of their biological features. The present study aimed at screening…”
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Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2024)“…Novel series of nitric oxide-releasing thiazolidine-2,4-diones ( ) and 3,4,5-trimethoxychalcone-based multifunctional 1,4-dihydropyrimidines ( ) have been…”
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10
In-vitro high-throughput library screening-Kinetics and molecular docking studies of potent inhibitors of α-glucosidase
Published in PloS one (30-06-2023)“…High throughput screening of synthetic compounds against vital enzymes is the way forward for the determination of potent enzyme inhibitors. In-vitro high…”
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11
Exploring the Potential of Phytocompounds for Targeting Epigenetic Mechanisms in Rheumatoid Arthritis: An In Silico Study Using Similarity Indexing
Published in Molecules (Basel, Switzerland) (01-03-2023)“…Finding structurally similar compounds in compound databases is highly efficient and is widely used in present-day drug discovery methodology. The most-trusted…”
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12
Polyphenol-enriched Desmodium elegans DC. ameliorate scopolamine-induced amnesia in animal model of Alzheimer’s disease: In Vitro, In Vivo and In Silico approaches
Published in Biomedicine & pharmacotherapy (01-09-2023)“…The current study aims to quantify HPLC-DAD polyphenolics in the crude extracts of Desmodium elegans, evaluating its cholinesterase inhibitory, antioxidant,…”
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New Succinimide-Thiazolidinedione Hybrids as Multitarget Antidiabetic Agents: Design, Synthesis, Bioevaluation, and Molecular Modelling Studies
Published in Molecules (Basel, Switzerland) (26-01-2023)“…Diabetes mellitus (DM) is a metabolic disorder majorly arising from the pathophysiology of the pancreas manifested as a decline in the insulin production or…”
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Characterization of Bioactive Compounds from Acacia concinna and Citrus limon , Silver Nanoparticles' Production by A. concinna Extract, and Their Biological Properties
Published in Molecules (Basel, Switzerland) (22-04-2022)“…The applications of bioactive compounds from medicinal plants as therapeutic drugs are largely increasing. The present study selected the bioactive compounds…”
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Synthesis, molecular docking study and biological evaluation of new pyrrole scaffolds as potential antitubercular agents for dual targeting of enoyl ACP reductase and dihydrofolate reductase
Published in PloS one (13-05-2024)“…In this study, new series of N'-(2-(substitutedphenoxy)acetyl)-4-(1H-pyrrol-1-yl)benzohydrazides (3a-j)…”
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Biological Evaluation, Phytochemical Screening, and Fabrication of Indigofera linifolia Leaves Extract-Loaded Nanoparticles
Published in Molecules (Basel, Switzerland) (23-07-2022)“…Indigofera linifolia is a medicinally important plant, and by virtue of its rich phytochemical composition, this plant is widely used as essential component in…”
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Synthesis, Molecular Docking, and Preclinical Evaluation of a New Succinimide Derivative for Cardioprotective, Hepatoprotective and Lipid-Lowering Effects
Published in Molecules (Basel, Switzerland) (21-09-2022)“…Cardiac and hepatotoxicities are major concerns in the development of new drugs. Better alternatives to other treatments are being sought to protect these…”
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Exploration of Succinimide Derivative as a Multi-Target, Anti-Diabetic Agent: In Vitro and In Vivo Approaches
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Diabetes mellitus (DM) is counted among one of the leading challenges in the recent era, and it is a life-threatening disorder. Compound 4-hydroxy 3-methoxy…”
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Deacetylated Sialic Acid Sensitizes Lung and Colon Cancers to Novel Cucurbitacin-Inspired Estrone Epidermal Growth Factor Receptor (EGFR) Inhibitor Analogs
Published in Molecules (Basel, Switzerland) (26-08-2023)“…Cancers utilize sugar residues such as sialic acids (Sia) to improve their ability to survive. Sia presents a variety of functional group alterations,…”
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In Silico Study on the Interactions, Molecular Docking, Dynamics and Simulation of Potential Compounds from Withania somnifera (L.) Dunal Root against Cancer by Targeting KAT6A
Published in Molecules (Basel, Switzerland) (22-01-2023)“…Cancer is characterized by the abnormal development of cells that divide in an uncontrolled manner and further take over the body and destroy the normal cells…”
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