Search Results - "Mahmoud, Sara"
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Naturally Available Flavonoid Aglycones as Potential Antiviral Drug Candidates against SARS-CoV-2
Published in Molecules (Basel, Switzerland) (29-10-2021)“…Flavonoids are important secondary plant metabolites that have been studied for a long time for their therapeutic potential in inflammatory diseases because of…”
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2
Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila
Published in Nature (London) (20-08-2020)“…Sexual dimorphism arises from genetic differences between male and female cells, and from systemic hormonal differences 1 – 3 . How sex hormones affect…”
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Activation of β-Catenin Signaling and its Crosstalk With Estrogen and Histone Deacetylases in Human Uterine Fibroids
Published in The journal of clinical endocrinology and metabolism (01-04-2020)“…Abstract Context Uterine fibroids (UF) are the most common benign tumor of the myometrium (MM) in women of reproductive age. However, the mechanism underlying…”
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4
Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo Studies
Published in Molecules (Basel, Switzerland) (27-09-2021)“…In response to the urgent need to control Coronavirus disease 19 (COVID-19), this study aims to explore potential anti-SARS-CoV-2 agents from natural sources…”
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5
Impact of settings and culture on nurses’ knowledge of and attitudes and perceptions towards people with dementia: An integrative literature review
Published in Nursing open (01-01-2022)“…Background Well‐trained nurses are required to support dementia patients; however, the quality of the provided dementia nursing care can be impacted by nurses’…”
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Flavonoids are promising safe therapy against COVID-19
Published in Phytochemistry reviews (01-02-2022)“…Flavonoids are a class of phenolic natural products, well-identified in traditional and modern medicines in the treatment of several diseases including viral…”
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Tuning structural, electrical, linear, and nonlinear optical properties of cadmium zinc telluride quantum dot thin films
Published in Journal of materials research (28-01-2023)“…Quantum dots of Cd 0.18 Zn 0.14 Te 0.68 thin films of various thicknesses are deposited on a glass substrate using inert gas condensation and characterized…”
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Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment
Published in Acta pharmacologica Sinica (01-07-2019)“…Uterine fibroids (UFs) are the most common benign neoplastic threat to women’s health and associated with DNA damage and genomic instability. Hypovitaminosis D…”
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Targeting SARS-CoV-2 endoribonuclease: a structure-based virtual screening supported by in vitro analysis
Published in Scientific reports (03-08-2022)“…Researchers are focused on discovering compounds that can interfere with the COVID-19 life cycle. One of the important non-structural proteins is…”
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A structural-based virtual screening and in vitro validation reveals novel effective inhibitors for SARS-CoV-2 helicase and endoribonuclease
Published in Journal of biomolecular structure & dynamics (21-11-2024)“…Researchers worldwide are looking for molecules that might disrupt the COVID-19 life cycle. Endoribonuclease, which is responsible for processing viral RNA to…”
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FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2
Published in Pharmaceuticals (Basel, Switzerland) (04-12-2020)“…(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as…”
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Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies
Published in Heliyon (01-09-2021)“…Drug repurposing is an important approach to the assignment of already approved drugs for new indications. This technique bypasses some steps in the…”
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Incidence, household transmission, and neutralizing antibody seroprevalence of Coronavirus Disease 2019 in Egypt: Results of a community-based cohort
Published in PLoS pathogens (01-03-2021)“…SARS-CoV-2 virus is transmitted in closed settings to people in contact with COVID-19 patients such as healthcare workers and household contacts. However,…”
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SmartCityWare: A Service-Oriented Middleware for Cloud and Fog Enabled Smart City Services
Published in IEEE access (01-01-2017)“…Smart cities are becoming a reality. Various aspects of modern cities are being automated and integrated with information and communication technologies to…”
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Incidence and neutralizing antibody seroprevalence of influenza B virus in Egypt: Results of a community-based cohort study
Published in PloS one (29-06-2022)“…Since 2000, two lineages of influenza B viruses, Victoria and Yamagata, have been circulating at similar frequencies worldwide. Little is known about the…”
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In Silico and In Vivo Evaluation of SARS-CoV-2 Predicted Epitopes-Based Candidate Vaccine
Published in Molecules (Basel, Switzerland) (13-10-2021)“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, the causative agent of coronavirus disease (COVID-19)) has caused relatively high mortality rates…”
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In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2
Published in PloS one (25-04-2024)“…There is still a great global need for efficient treatments for the management of SARS-CoV-2 illness notwithstanding the availability and efficacy of COVID-19…”
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Chemical Profile, Antibacterial, Antibiofilm, and Antiviral Activities of Pulicaria crispa Most Potent Fraction: An In Vitro and In Silico Study
Published in Molecules (Basel, Switzerland) (19-05-2023)“…Infectious diseases caused by viruses and bacteria are a major public health concern worldwide, with the emergence of antibiotic resistance, biofilm-forming…”
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Common childhood vaccines do not elicit a cross-reactive antibody response against SARS-CoV-2
Published in PloS one (28-10-2020)“…Anecdotal evidence showed a negative correlation between Bacille Calmette-Guérin (BCG) vaccination and incidence of COVID-19. Incidence of the disease in…”
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Antiviral activities of plant-derived indole and β-carboline alkaloids against human and avian influenza viruses
Published in Scientific reports (28-01-2023)“…The persistent evolution of drug-resistant influenza strains represents a global concern. The innovation of new treatment approaches through drug screening…”
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