Search Results - "Mahmoud, Nevertyty M."
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Canagliflozin protects against non-alcoholic steatohepatitis in type-2 diabetic rats through zinc alpha-2 glycoprotein up-regulation
Published in European journal of pharmacology (05-06-2018)“…Elevated blood glucose and insulin resistance are triggering factors for non-alcoholic steatohepatitis (NASH). We investigated the effects of the Sodium…”
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Geraniol protects against cyclosporine A-induced renal injury in rats: Role of Wnt/β-catenin and PPARγ signaling pathways
Published in Life sciences (1973) (15-02-2022)“…The nephrotoxicity of cyclosporine A (CsA) limits its use as an immunosuppressant. Wnt/β-catenin signaling is involved in the pathogenesis of both acute and…”
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Agomelatine improves streptozotocin-induced diabetic nephropathy through melatonin receptors/SIRT1 signaling pathway
Published in International immunopharmacology (01-02-2023)“…[Display omitted] •Agomelatine increased renal SIRT1 expression in STZ-treated rats.•Agomelatine improved diabetes and insulin resistance.•Agomelatine improved…”
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Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway
Published in European journal of pharmacology (15-08-2020)“…The phosphodiesterase-3 inhibitor, cilostazol has been recently shown to protect against chemically induced colitis in animal models. However, whether cyclic…”
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Rebamipide protects against experimentally induced intestinal ischemia/reperfusion-promoted liver damage: Impact on SIRT1/β-catenin/FOXO1and NFκB signaling
Published in International immunopharmacology (01-06-2023)“…•Intestinal I/R is a life-threatening condition associated with high morbidity and mortality rates.•Intestinal I/R is suggested to be the principal cause of…”
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LncRNA ANRIL Promotes Glucose Metabolism and Proliferation of Colon Cancer in a High-Glucose Environment and is Associated with Worse Outcome in Diabetic Colon Cancer Patients
Published in Asian Pacific journal of cancer prevention : APJCP (01-04-2024)“…The potential involvement of type 2 diabetes mellitus (T2DM) as a risk factor for colon cancer (CC) has been previously reported. Epigenetic changes, such as…”
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Alagebrium Mitigates Metabolic Insults in High Carbohydrate and High Fat Diet Fed Wistar Rats
Published in Pharmaceutical Sciences (01-03-2020)“…Background : Metabolic syndrome (MS) is characterized by sustained hyperglycemia that triggers advanced glycation end products (AGEs) generation. Alagebrium…”
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AMELIORATIVE EFFECT OF VITAMIN E AGAINST SOME ADVERSE EFFECTS OF LEVOFLOXACIN IN MALE RATS
Published in Assiut veterinary medical journal (01-04-2020)Get full text
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