Search Results - "Mahmoud, Amr"
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1
Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats
Published in PloS one (09-09-2014)“…The metabolic syndrome (MS) is characterized by insulin resistance, dyslipidemia and hypertension. It is associated with increased risk of cardiovascular…”
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2
True aneurysm of the dorsalis pedis artery
Published in Vascular (01-04-2023)“…Aneurysm of the pedal arteries is uncommon. I present a case of non-traumatic fusiform true aneurysm of the dorsalis pedis artery in an otherwise well…”
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3
Impact of some oral hypoglycemic agents on type 2 diabetes-associated depression and reserpine-induced depression in rats: the role of brain oxidative stress and inflammation
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2020)“…Diabetes mellitus and depression are comorbid diseases affecting many patients all over the world. The current study was designed to compare the antidepressant…”
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4
Deep Learning Model for Efficient Protein–Ligand Docking with Implicit Side-Chain Flexibility
Published in Journal of chemical information and modeling (27-03-2023)“…Protein–ligand docking is an essential tool in structure-based drug design with applications ranging from virtual high-throughput screening to pose prediction…”
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5
Point-of-care diagnostics for therapeutic monitoring of levofloxacin in human plasma utilizing electrochemical sensor mussel-inspired molecularly imprinted copolymer
Published in Journal of electroanalytical chemistry (Lausanne, Switzerland) (01-08-2022)“…•Fabrication of MIP electrochemical sensor to personalize the Levofloxacin dose.•Bio-inspired molecularly imprinted copolymer was synthesized utilizing…”
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6
Introducing 3-Dimensional Printing of a Human Anatomic Pathology Specimen: Potential Benefits for Undergraduate and Postgraduate Education and Anatomic Pathology Practice
Published in Archives of pathology & laboratory medicine (1976) (01-08-2015)“…Three-dimensional (3D) printing, a rapidly advancing technology, is widely applied in fields such as mechanical engineering and architecture. Three-dimensional…”
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7
Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B
Published in Toxicology letters (01-10-2018)“…The proposed mechanism of action for sorafenib, perindopril, fosinopril and losartan in interfering with NFκB pathway. Ang, angiotensin; AT1R, angiotensin II…”
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8
The renoprotective effect of glycyrrhizic acid in insulin-resistant rats exposed to aluminum involves the inhibition of TLR4/NF-κB signaling pathway
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-05-2021)“…Aluminum is well recognized as a nephrotoxic agent. Its hazardous effects arise from the high risk of daily exposure. The consumption of fructose also…”
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9
Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin
Published in Life sciences (1973) (01-12-2021)“…β-Arrestin2 signaling has emerged as a promising therapeutic target for the management of insulin resistance and related complications. Moreover, recent…”
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10
Comparison of Long Term Outcomes After Endovascular Treatment Versus Bypass Surgery in Chronic Limb Threatening Ischaemia Patients with Long Femoropopliteal Lesions
Published in European journal of vascular and endovascular surgery (01-02-2021)“…There are currently two treatments available for patients with chronic limb threatening ischaemia (CLTI): open surgical bypass (OSB) and percutaneous…”
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11
A comparative analysis of current phasing and imputation software
Published in PloS one (19-10-2022)“…Whole-genome data has become significantly more accessible over the last two decades. This can largely be attributed to both reduced sequencing costs and…”
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12
Prolonged overnutrition with fructose or fat induces metabolic derangements in rats by disrupting the crosstalk between the hypothalamus and periphery: Possible amelioration with fenofibrate
Published in European journal of pharmacology (15-07-2020)“…Metabolic Syndrome (MetS) increases the risk of developing type 2 diabetes mellitus and cardiovascular complications. The crosstalk between the hypothalamus…”
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13
Accurate Sampling of Macromolecular Conformations Using Adaptive Deep Learning and Coarse-Grained Representation
Published in Journal of chemical information and modeling (11-04-2022)“…Conformational sampling of protein structures is essential for understanding biochemical functions and for predicting thermodynamic properties such as free…”
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14
Dynamic Lyapunov Machine Learning Control of Nonlinear Magnetic Levitation System
Published in Energies (Basel) (01-03-2022)“…This paper presents a novel dynamic deep learning architecture integrated with Lyapunov control to address the timing latency and constraints of deep learning…”
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15
Effect of omega-3 fatty acids on glucose homeostasis: role of free fatty acid receptor 1
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-10-2020)“…Insulin resistance is a worldwide health problem. This study investigated the acute effects of eicosapentanoic acid (EPA) on glucose homeostasis focusing on…”
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16
Point-of-care electrochemical sensor for selective determination of date rape drug “ketamine” based on core-shell molecularly imprinted polymer
Published in Talanta (Oxford) (01-03-2023)“…Misuse of illicit drugs is a serious problem that became the primary concern for many authorities worldwide. Point-of-care (POC) diagnostic tools can provide…”
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17
Antifibrotic activity of hesperidin against dimethylnitrosamine-induced liver fibrosis in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-06-2014)“…Hepatic fibrosis is a significant health problem that may progress to cirrhosis and cancer. It may be caused by viruses or chemicals such as…”
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18
Novel solid-contact ion-selective electrode based on a polyaniline transducer layer for determination of alcaftadine in biological fluid
Published in RSC advances (01-03-2023)“…Fabrication of a novel ion selective electrode for determining alcaftadine was achieved. The glassy carbon electrode (GCE) was utilized as a substrate in…”
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19
Univariate and Multivariate Determination of Dapagliflozin and Saxagliptin in Bulk and Dosage Form
Published in Journal of AOAC International (03-05-2023)“…Dapagliflozin is a sodium glucose cotransporter-II inhibitor while saxagliptin is a dipeptidyl peptidase-4 inhibitor. Both are used to manage type 2 diabetes…”
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20
A new combination of sitagliptin and furosemide protects against remote myocardial injury induced by renal ischemia/reperfusion in rats
Published in Biochemical pharmacology (01-07-2015)“…Acute kidney injury (AKI) is associated with high mortality resulting from extra-renal organ damage, particularly the heart. The present study aimed to…”
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