Search Results - "Mahmoud, Abeer E."
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Silymarin enhances the response to oxytetracycline treatment in Oreochromis niloticus experimentally infected with Aeromonas hydrophila
Published in Scientific reports (27-09-2023)“…Many governments have approved the use of oxytetracycline as an antibiotic additive to food fish, with oxytetracycline now routinely used in many nations…”
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Synthesis and anticancer effects of some novel pyrazolo[3,4- d]pyrimidine derivatives by generating reactive oxygen species in human breast adenocarcinoma cells
Published in European journal of medicinal chemistry (01-04-2011)“…A series of novel substituted pyrazolo[3,4- d]pyrimidines (compounds 2– 12) were synthesized starting with pyrimidinone derivative 1. Their in vitro…”
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3
Targeting Receptor Tyrosine Kinase VEGFR-2 in Hepatocellular Cancer: Rational Design, Synthesis and Biological Evaluation of 1,2-Disubstituted Benzimidazoles
Published in Molecules (Basel, Switzerland) (11-02-2020)“…In this study, a novel series of 1,2-disubstituted benzo[d]imidazoles was rationally designed as VEGFR-2 inhibitors targeting hepatocellular carcinoma. Our…”
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Enhancing the antioxidant properties of functional herbal beverages using Ultrasonic-Assisted extraction: Optimized formulation and synergistic combinations of taurine and vit. C
Published in Heliyon (15-08-2024)“…Functional herbal beverages are gaining popularity in the beverage industry due to their natural antioxidants. However, the high concentration of antioxidants…”
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Mass kills in hatchery-reared European seabass (Dicentrarchus labrax) triggered by concomitant infections of Amyloodinium ocellatum and Vibrio alginolyticus
Published in International journal of veterinary science and medicine (31-12-2022)“…Amyloodiniosis and vibriosis are serious diseases in European seabass (Dicentrarchus labrax) hatcheries with noticeable high mortality. This study was…”
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Ameliorative effects of vitamins-loaded flavoured nanophytosomes fortified with star anise volatile oil against CsA-Induced liver and kidney injury in rats: Application in functional ice cream
Published in Heliyon (15-01-2024)“…This study investigated the effect of flavoured nanophytosomes loaded with vitamins A, E, D, B complex, folic acid, and C, as well as zinc on the…”
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Improving the nutritive value of olive pomace by solid state fermentation of Kluyveromyces marxianus with simultaneous production of gallic acid
Published in International journal of recycling of organic waste in agriculture (01-06-2018)“…Purpose Olive oil industry is a growing industrial sector in Mediterranean countries. Unfortunately, about 30–35% of total olive weight is discarded as olive…”
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Development of a functional cake with probiotics and micro-encapsulated essential oils: Evaluation of nutritional properties, liver protection, and immune boosting
Published in Heliyon (15-01-2024)“…This study used probiotics and micro-encapsulated clove and cinnamon oils to develop a functional cream-stuffed cake based on sweet potatoes flour and rice…”
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LATEX AGGLUTATION TEST AND PCR ASSAYS FOR DIAGNOSIS OF TOXOPLASMA GONDII INFECTION IN RED MEAT PRODUCING ANIMALS IN ASWAN GOVERNORATE, SOUTHERN EGYPT
Published in Slovenski veterinarski zbornik (01-01-2021)“…Livestock meat is considered a potential source of human infection, therefore evaluation of the infection rate with Toxoplasma gondii (T. gondii) in these…”
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10
M-RNA Gene Expression of INF-Γ and IL-10 during Intestinal Phase of Trichinella spiralis after Myrrh and Albendazole Treatment
Published in Iranian journal of parasitology (2017)“…The protective response developed against infection provokes immune and inflammatory responses mediated by cytokines released from T helper cells. We aimed to…”
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11
Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase
Published in Bioorganic chemistry (01-08-2020)“…[Display omitted] •New pyrazole derivatives were designed and synthesized.•Some compounds showed potent cytotoxic effect against MCF-7 and VEGFR-2…”
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12
Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis
Published in Bioorganic chemistry (01-04-2019)“…[Display omitted] •New thiazolylpyrazolyl coumarin derivatives were designed and synthesized.•Some compounds showed potent cytotoxic effect against MCF-7 and…”
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13
Temperature fluctuation alters immuno-antioxidant response and enhances the susceptibility of Oreochromis niloticus to Aeromonas hydrophila challenge
Published in Aquaculture international (01-04-2024)“…In Egypt, the temperature of the water fluctuates drastically, reaching a daytime high of 25 °C and a nighttime low of 15 °C, respectively, in the spring and…”
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Type IIA - Type IIB protein tyrosine kinase inhibitors hybridization as an efficient approach for potent multikinase inhibitor development: Design, synthesis, anti-proliferative activity, multikinase inhibitory activity and molecular modeling of novel indolinone-based ureides and amides
Published in European journal of medicinal chemistry (01-02-2019)“…Pursuing on our efforts regarding development of novel multikinase inhibitors, herein we report the design and synthesis of novel 2-indolinone-based ureides…”
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15
Novel potent substituted 4-amino-2-thiopyrimidines as dual VEGFR-2 and BRAF kinase inhibitors
Published in European journal of medicinal chemistry (01-10-2019)“…In the present study, we report the discovery of a novel class of substituted 4-amino-2-thiopyrimidines as antiangiogenic and antiproliferative agents…”
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Purification and characterization of a novel tannase produced by Kluyveromyces marxianus using olive pomace as solid support, and its promising role in gallic acid production
Published in International journal of biological macromolecules (01-02-2018)“…Tannase is considered one of the most important industrial enzymes that find great applications in various sectors. Production of tannases through solid state…”
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17
Light microscopical and parasitological analyses revealed the beneficial effects of silver nanoparticles and various myrrh extracts against Trichinella spiralis infection in mice
Published in Microscopy research and technique (01-07-2024)“…Trichinella spiralis infection is a food‐borne zoonotic disease caused by nematodes that dwell in the tissues, presenting a significant public health concern…”
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Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer
Published in Archiv der Pharmazie (Weinheim) (01-04-2020)“…A novel series of 2‐arylbenzothiazoles 9, 10, and 12 were designed and synthesized as VEGFR‐2/FGFR‐1/PDGFR‐β multiangiokinase inhibitors targeting breast…”
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19
Design, synthesis, and in silico insights of novel N’-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors
Published in Bioorganic chemistry (01-12-2024)“…[Display omitted] •Novel piperidine-tethered oxindole derivatives were reported as potential VEGFR-2 inhibitors.•Compound 12e showed the most potent VEGFR-2…”
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20
Effect of myrrh and thyme on Trichinella spiralis enteral and parenteral phases with inducible nitric oxide expression in mice
Published in Memórias do Instituto Oswaldo Cruz (01-12-2015)“…Trichinellosis is a serious disease with no satisfactory treatment. We aimed to assess the effect of myrrh (Commiphora molmol) and, for the first time, thyme…”
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