Search Results - "Mahmood, Hafiz M"

Green Synthesis, Characterization, Enzyme Inhibition, Antimicrobial Potential, and Cytotoxic Activity of Plant Mediated Silver Nanoparticle Using Ricinus communis Leaf and Root Extracts by Gul, Anadil, Fozia, Shaheen, Asmat, Ahmad, Ijaz, Khattak, Baharullah, Ahmad, Munir, Ullah, Riaz, Bari, Ahmed, Ali, Syed Saeed, Alobaid, Abdulrahman, Asmari, Majid M, Mahmood, Hafiz M

“…The need of non-toxic synthesis protocols for nanoparticles arises developing interest in biogenic approaches. The present project was focused on cost…”
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Genome-Based Drug Target Identification in Human Pathogen Streptococcus gallolyticus by Qureshi, Nosheen Afzal, Bakhtiar, Syeda Marriam, Faheem, Muhammad, Shah, Mohibullah, Bari, Ahmed, Mahmood, Hafiz M, Sohaib, Muhammad, Mothana, Ramzi A, Ullah, Riaz, Jamal, Syed Babar

“…( ) is an opportunistic Gram-positive, non-motile bacterium, which causes infective endocarditis, an inflammation of the inner lining of the heart. As has…”
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5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism by Alhosaini, Khaled, Ansari, Mushtaq A, Nadeem, Ahmed, Bakheet, Saleh A, Attia, Sabry M, Alhazzani, Khalid, Albekairi, Thamer H, Al-Mazroua, Haneen A, Mahmood, Hafiz M, Ahmad, Sheikh F

“…Autism spectrum disorder (ASD) covers a range of neurodevelopmental disorders involving impairments in communication and repetitive and stereotyped patterns of…”
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Antinematode Activity of Abomasum Bacterial Culture Filtrates against Haemonchus contortus in Small Ruminants by Nazish, Asfa, Fozia, Khattak, Baharullah, Ali Khan, Taj, Ahmad, Ijaz, Ullah, Riaz, Bari, Ahmed, Asmari, Majid M., Mahmood, Hafiz M., Sohaib, Muhammad, El Askary, Ahmad, El-kott, Attalla F., Abdel-Daim, Mohamed M.

“…Haemonchosis is a parasitic disease of small ruminants that adversely affects livestock production. Haemonchus contortus is one of the most prevalent nematode…”
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Dysregulation of Ki-67 Expression in T Cells of Children with Autism Spectrum Disorder by Alhosaini, Khaled, Ansari, Mushtaq A, Nadeem, Ahmed, Attia, Sabry M, Bakheet, Saleh A, Al-Ayadhi, Laila Y, Mahmood, Hafiz M, Al-Mazroua, Haneen A, Ahmad, Sheikh F

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by behavioral abnormalities such as impairments in social function and deficits…”
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Therapeutic treatment with Ibrutinib attenuates imiquimod-induced psoriasis-like inflammation in mice through downregulation of oxidative and inflammatory mediators in neutrophils and dendritic cells by Al-Harbi, Naif O., Nadeem, Ahmed, Ahmad, Sheikh F., Bakheet, Saleh A., El-Sherbeeny, Ahmad M., Ibrahim, Khalid E., Alzahrani, Khalid S., Al-Harbi, Mohammed M., Mahmood, Hafiz M., Alqahtani, Faleh, Attia, Sabry M., Alotaibi, Moureq R.

“…Psoriasis is clinically characterized by well-demarcated silvery plaques which may appear on the extremities, scalp, and sacral area. The multidimensional…”
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The α9α10 nicotinic acetylcholine receptors antagonist α-conotoxin RgIA reverses colitis signs in murine dextran sodium sulfate model by AlSharari, Shakir D., Toma, Wisam, Mahmood, Hafiz M., Michael McIntosh, J., Imad Damaj, M.

“…Nicotinic acetylcholine receptors can regulate inflammation primarily through the vagus nerve via the cholinergic anti-inflammatory pathway. α9α10 nicotinic…”
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CXC chemokine receptor 3 antagonist AMG487 shows potent anti-arthritic effects on collagen-induced arthritis by modifying B cell inflammatory profile by Bakheet, Saleh A., Alrwashied, Bader S., Ansari, Mushtaq A., Nadeem, Ahmed, Attia, Sabry M., Alanazi, Mohammed M., Aldossari, Abdullah A., Assiri, Mohammed A., Mahmood, Hafiz M., Al-Mazroua, Haneen A., Ahmad, Sheikh F.

“…[Display omitted] •We investigated the effect of AMG487 on the key mediators of RA.•AMG487 treatment downregulated NF-κB signaling in collagen-induced…”
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Bruton’s tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice by Nadeem, Ahmed, Ahmad, Sheikh F., Al-Harbi, Naif O., Ibrahim, Khalid E., Alqahtani, Faleh, Alanazi, Wael A, Mahmood, Hafiz M, Alsanea, Sary, Attia, Sabry M

“…•Upregulation of BTK signaling in neutrophils, DCs and B cells in AKI.•Upregulation of NOX2/iNOS/oxidative stress in neutrophils, DCs and B cells in AKI.•BTK…”
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Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/STAT pathway in the BTBR mouse model of autism by Ahmad, Sheikh F., Ansari, Mushtaq A., Nadeem, Ahmed, Bakheet, Saleh A., Alsanea, Sary, Al-Hosaini, Khaled A., Mahmood, Hafiz M., Alzahrani, Mohammad Z., Attia, Sabry M.

“…•The tyrosine kinase inhibitor AG126 attenuates IL-21R/IL-21 cytokines in BTBR mice.•AG126 downregulates pro-inflammatory and JAK/STAT signaling in BTBR…”
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Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells by Nadeem, Ahmed, Al-Harbi, Naif O., Ahmad, Sheikh F., Alhazzani, Khalid, Attia, Sabry M., Alsanea, Sary, Alhoshani, Ali, Mahmood, Hafiz M., Alfardan, Ali S., Bakheet, Saleh A.

“…Epigenetic modifications are known to play a crucial role in the behavioral modifications through regulation of gene expression. Environmental factors are…”
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The Stat3 inhibitor, S3I-201, downregulates lymphocyte activation markers, chemokine receptors, and inflammatory cytokines in the BTBR T+ Itpr3tf/J mouse model of autism by Ahmad, Sheikh F., Ansari, Mushtaq A., Nadeem, Ahmed, Bakheet, Saleh A., Alanazi, Ahmed Z., Alsanea, Sary, As Sobeai, Homood M., Almutairi, Mashal M., Mahmood, Hafiz M., Attia, Sabry M.

“…•BTBR mice experienced a significant induction in activation marker expression.•S3I-201 decreased activation markers and inflammatory cytokines in BTBR…”
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The Role of Nicotinic Receptors in the Attenuation of Autism‐Related Behaviors in a Murine BTBR T + tf/J Autistic Model by Mahmood, Hafiz M., Aldhalaan, Hesham M., Alshammari, Tahani K., Alqasem, Mashael A., Alshammari, Musaad A., Albekairi, Norah A., AlSharari, Shakir D.

“…Nicotinic receptors are distributed throughout the central and peripheral nervous system. Postmortem studies have reported that some nicotinic receptor…”
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The Stat3 inhibitor, S3I-201, downregulates lymphocyte activation markers, chemokine receptors, and inflammatory cytokines in the BTBR T + Itpr3 tf /J mouse model of autism by Ahmad, Sheikh F, Ansari, Mushtaq A, Nadeem, Ahmed, Bakheet, Saleh A, Alanazi, Ahmed Z, Alsanea, Sary, As Sobeai, Homood M, Almutairi, Mashal M, Mahmood, Hafiz M, Attia, Sabry M

“…Autism is a complex neurodevelopmental disorder with a high incidence rate. It is characterized by deficits in communication, a lack of social skills,…”
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