Search Results - "Mahlapuu, M"

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3) by Nerstedt, A, Johansson, A, Andersson, C. X, Cansby, E, Smith, U, Mahlapuu, M

“…Aim/hypothesis The aim of the study was to examine the possible role of AMP-activated protein kinase (AMPK) in the regulation of the inflammatory response…”
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The 5 '-AMP-activated protein kinase gamma 3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle by Barnes, B.R., Marklund, S., Steiler, T.L., Walter, M., Hjalm, G., Amarger, Valérie, Mahlapuu, M., Leng, Y., Johansson, C., Galuska, D., Lindgren, K., Abrink, M., Stapleton, D., Zierath, J.R., Andersson, L.

“…absent…”
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The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm by Mahlapuu, M, Ormestad, M, Enerbäck, S, Carlsson, P

“…The murine Foxf1 gene encodes a forkhead transcription factor expressed in extra-embryonic and lateral plate mesoderm and later in splanchnic mesenchyme…”
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STK25 is a critical determinant in nonalcoholic steatohepatitis by Mahlapuu, M, Amrutkar, M, Chursa, U, Nuñez-Duran, E, Borén, J, Johansson, B.R, Marschall, H.-U, Blüher, M, Cansby, E

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Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations by Mahlapuu, M, Enerbäck, S, Carlsson, P

“…The murine Foxf1 gene, encoding a forkhead – or winged helix – transcription factor, is expressed in splanchnic mesenchyme during organogenesis. The…”
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Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle by Nerstedt, A., Cansby, E., Andersson, C. X., Laakso, M., Stančáková, A., Blüher, M., Smith, U., Mahlapuu, M.

“…Aims/hypothesis This study investigates the role of serine/threonine protein kinase 25 (STK25), a member of the sterile 20 (STE20) superfamily of kinases, in…”
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Protein Kinase STK25 Controls Lipid Partitioning in Human Hepatocytes and Correlates with Liver Fat Content in Man by Mahlapuu, M, Amrutkar, M, Kern, M, Nuñez-Durán, E, Ståhlman, M, Borén, J, Blüher, M

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A lactoferrin-derived peptide (PXL01) for the reduction of adhesion formation in flexor tendon surgery: an experimental study in rabbits by Wiig, M., Olmarker, K., Håkansson, J., Ekström, L., Nilsson, E., Mahlapuu, M.

“…Injuries to flexor tendons can lead to loss of finger function after healing due to adhesion formation. The aim of this study was to assess the efficacy and…”
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Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle by LONG, Y. C, BARNES, B. R, MAHLAPUU, M, STEILER, T. L, MARTINSSON, S, LENG, Y, WALLBERG-HENRIKSSON, H, ANDERSSON, L, ZIERATH, J. R

“…AMP-activated protein kinase (AMPK) regulates metabolic adaptations in skeletal muscle. The aim of this study was to investigate whether AMPK modulates the…”
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Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle by NERSTEDT, A, CANSBY, E, ANDERSSON, C. X, LAAKSO, M, STANCAKOVA, A, BLÜHER, M, SMITH, U, MAHLAPUU, M

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Antimicrobial peptides as therapeutic agents: opportunities and challenges by Mahlapuu, Margit, Björn, Camilla, Ekblom, Jonas

“…The rapid development of microbial resistance to conventional antibiotics has accelerated efforts to find anti-infectives with a novel mode-of-action, which…”
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Cubosomes for topical delivery of the antimicrobial peptide LL-37 by Boge, Lukas, Hallstensson, Karin, Ringstad, Lovisa, Johansson, Jenny, Andersson, Therese, Davoudi, Mina, Larsson, Per Tomas, Mahlapuu, Margit, Håkansson, Joakim, Andersson, Martin

“…[Display omitted] In this study, the use of cubosomes for topical delivery of the antimicrobial peptide (AMP) LL-37 was investigated. Topical delivery of AMPs…”
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Forkhead Transcription Factors: Key Players in Development and Metabolism by Carlsson, Peter, Mahlapuu, Margit

“…Forkhead proteins are not among the largest transcription factor families, but display a remarkable functional diversity and are involved in a wide variety of…”
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Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial by Grönberg, Alvar, Mahlapuu, Margit, Ståhle, Mona, Whately-Smith, Caroline, Rollman, Ola

“…Venous leg ulcers (VLUs) are one of the most prevalent types of chronic wounds. The aim of this study was to determine the safety and dose–response efficacy of…”
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Antimicrobial Peptides: An Emerging Category of Therapeutic Agents by Mahlapuu, Margit, Håkansson, Joakim, Ringstad, Lovisa, Björn, Camilla

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Antimicrobial synergy of monolaurin lipid nanocapsules with adsorbed antimicrobial peptides against Staphylococcus aureus biofilms in vitro is absent in vivo by Rozenbaum, René T., Su, Linzhu, Umerska, Anita, Eveillard, Matthieu, Håkansson, Joakim, Mahlapuu, Margit, Huang, Fan, Liu, Jianfeng, Zhang, Zhenkun, Shi, Linqi, van der Mei, Henny C., Busscher, Henk J., Sharma, Prashant K.

“…Bacterial infections are mostly due to bacteria in their biofilm-mode of growth, while penetrability of antimicrobials into infectious biofilms and increasing…”
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Anti-infective efficacy of the lactoferrin-derived antimicrobial peptide HLR1r by Björn, Camilla, Mahlapuu, Margit, Mattsby-Baltzer, Inger, Håkansson, Joakim

“…•The peptide HLR1r demonstrates a broad spectrum microbicidal action in vitro.•HLR1r displays anti-inflammatory properties in vitro without any cytotoxic…”
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SAT-318 - Protein Kinase STK25 Controls Lipid Partitioning in Human Hepatocytes and Correlates with Liver Fat Content in Man by Mahlapuu, M., Amrutkar, M., Kern, M., Nuñez-Durán, E., Ståhlman, M., Borén, J., Blüher, M.

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FRI-366 - STK25 is a critical determinant in nonalcoholic steatohepatitis by Mahlapuu, M., Amrutkar, M., Chursa, U., Nuñez-Duran, E., Borén, J., Johansson, B.R., Marschall, H.-U., Blüher, M., Cansby, E.

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Dendritic Nanogels Directed Dual‐Encapsulation Topical Delivery System of Antimicrobial Peptides Targeting Skin Infections by Zhang, Yuning, Håkansson, Joakim, Fan, Yanmiao, Andrén, Oliver C. J., San Jacinto García, Jorge, Qin, Liguo, Umerska, Anita, Hutchinson, Daniel J., Lüchow, Mads, Mahlapuu, Margit, Malkoch, Michael

“…Antimicrobial peptides (AMPs) are promising antibacterial agents in the fight against multidrug resistant pathogens. However, their application to skin…”
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