Search Results - "Mahindroo, N."
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Alcohol-based hand sanitisers as first line of defence against SARS-CoV-2: a review of biology, chemistry and formulations
Published in Epidemiology and infection (01-01-2020)“…The pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has emerged as a serious global public health issue. Since the start of the…”
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Pharmaceutical design of antimitotic agents based on combretastatins
Published in Current pharmaceutical design (01-05-2005)“…The design of novel anticancer agents based on the combretastatins, a group of antimitotic agents isolated from the bark of the South African willow tree…”
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Meningeal tuberculosis secondary to an unusual primary site
Published in Journal of the Association of Physicians of India (01-10-1996)Get more information
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Structure-Based Drug Design of a Novel Family of PPARγ Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities
Published in Journal of medicinal chemistry (04-05-2006)“…Peroxisome proliferator-activated receptor γ (PPARγ) is well-known as the receptor of thiazolidinedione antidiabetic drugs. In this paper, we present a…”
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Synthesis and Structure−Activity Relationships of 3-Aminobenzophenones as Antimitotic Agents
Published in Journal of medicinal chemistry (20-05-2004)“…A new series of 3-aminobenzophenone compounds as potent inhibitors of tubulin polymerization was discovered based on the mimic of the aminocombretastatin…”
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Study of auditory brainstem responses in presbyacusis
Published in Indian Journal of Otolaryngology and Head and Neck Surgery (01-03-1997)“…The results of auditory brainstem evoked responses in 25 subjects of presbyacusis are compared with 25 age and sex matched controls. Absolute latent periods of…”
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Indol-1-yl Acetic Acids as Peroxisome Proliferator-Activated Receptor Agonists: Design, Synthesis, Structural Biology, and Molecular Docking Studies
Published in Journal of medicinal chemistry (09-02-2006)“…A series of novel indole-based PPAR agonists is described leading to discovery of 10k, a highly potent PPAR pan-agonist. The structural biology and molecular…”
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Structure–activity and crystallographic analysis of benzophenone derivatives—the potential anticancer agents
Published in Bioorganic & medicinal chemistry letters (06-01-2003)“…Compounds 1– 5, structurally related to combretastatin A-4 showed excellent cytotoxic activities against a panel of human cancer cell lines including…”
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Benzothiazolium compounds: novel classes of inhibitors that suppress the nitric oxide production in RAW264.7 cells stimulated by LPS/IFNγ
Published in Bioorganic & medicinal chemistry letters (15-04-2005)“…[Display omitted] A series of benzothiazolium compounds were identified as novel classes of inhibitors of nitric oxide production in a cell culture system…”
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