Search Results - "Mahgoub, Sebaey"

Phytochemical Profiling, In Vitro and In Silico Anti-Microbial and Anti-Cancer Activity Evaluations and Staph GyraseB and h -TOP-IIβ Receptor-Docking Studies of Major Constituents of Zygophyllum coccineum L. Aqueous-Ethanolic Extract and Its Subsequent Fractions: An Approach to Validate Traditional Phytomedicinal Knowledge by Mohammed, Hamdoon A, Khan, Riaz A, Abdel-Hafez, Atef A, Abdel-Aziz, Marwa, Ahmed, Eman, Enany, Shymaa, Mahgoub, Sebaey, Al-Rugaie, Osamah, Alsharidah, Mansour, Aly, Mohamed S A, Mehany, Ahmed B M, Hegazy, Mostafa M

“…, an edible halophytic plant, is part of the traditional medicine chest in the Mediterranean region for symptomatic relief of diabetes, hypertension, wound…”
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A Novel Approach of SWATH-Based Metabolomics Analysis Using the Human Metabolome Database Spectral Library by Shikshaky, Hassan, Ahmed, Eman Abdelnaby, Anwar, Ali Mostafa, Osama, Aya, Ezzeldin, Shahd, Nasr, Antony, Mahgoub, Sebaey, Magdeldin, Sameh

“…Metabolomics is a potential approach to paving new avenues for clinical diagnosis, molecular medicine, and therapeutic drug monitoring and development. The…”
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Integrated multiomics analysis to infer COVID-19 biological insights by Sameh, Mahmoud, Khalaf, Hossam M., Anwar, Ali Mostafa, Osama, Aya, Ahmed, Eman Ali, Mahgoub, Sebaey, Ezzeldin, Shahd, Tanios, Anthony, Alfishawy, Mostafa, Said, Azza Farag, Mohamed, Maged Salah, Sayed, Ahmed A., Magdeldin, Sameh

“…Three years after the pandemic, we still have an imprecise comprehension of the pathogen landscape and we are left with an urgent need for early detection…”
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Anticancer Effect of Cycas media: Molecular Basis Through Modulation of PI3K/AKT/mTOR Signaling Pathway by Alqahtani, Jawaher, Mosalam, Esraa M, Abo Mansour, Hend E, Elberri, Aya Ibrahim, Ibrahim, Hanaa A, Mahgoub, Sebaey, Hussein, Ismail A, Hawwal, Mohammed F, Al Hmoudi, Maryam, Moglad, Ehssan, Ahmed, Rehab, Mokhtar, Fatma Alzahraa, Elekhnawy, Engy, Negm, Walaa A

“…Many researchers are focusing on screening the biological activities of plants owing to their safety and possible pharmacological actions. Consequently, we…”
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The medicinal activity of lyophilized aqueous seed extract of Lepidium sativum L. in an androgenic alopecia model by Albalawi, Marzough Aziz, Hafez, Ahmed M., Elhawary, Seham S., Sedky, Nada K., Hassan, Omnia F., Bakeer, Rofanda M., El Hadi, Soha Abd, El-Desoky, Ahmed H., Mahgoub, Sebaey, Mokhtar, Fatma A.

“…This study evaluated the topical effect of Lepidium sativum lyophilized seed extract (LSLE) towards Sustanon-induced alopecia in male adult Wistar albino rats…”
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Anti-inflammatory potential of Penicillium brefeldianum endophytic fungus supported with phytochemical profiling by Saleh, Asmaa, Negm, Walaa A, El-Masry, Thanaa A, Eliwa, Duaa, Alotaibi, Badriyah, Alosaimi, Manal E, Alotaibi, Khalid Nijr, Magdeldin, Sameh, Mahgoub, Sebaey, Elekhnawy, Engy

“…Various factors contribute to the development of the acute inflammation process, like the pro-inflammatory cytokines, certain enzymes as well as oxidative…”
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Antibacterial and anti-Toxoplasma activities of Aspergillus niger endophytic fungus isolated from Ficus retusa: in vitro and in vivo approach by Moglad, Ehssan, Elekhnawy, Engy, Negm, Walaa A., Eliwa, Duaa, Sami Younis, Salwa, Mohamed Elmansory, Basma, Mahgoub, Sebaey, Ahmed, Eman A., Momtaz Al-Fakhrany, Omnia

“…Emergent records propose that Aspergillus niger endophytic fungus is a vital source for various bioactive molecules possessing many biological properties. The…”
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gtAI: an improved species-specific tRNA adaptation index using the genetic algorithm by Anwar, Ali Mostafa, Khodary, Saif M, Ahmed, Eman Ali, Osama, Aya, Ezzeldin, Shahd, Tanios, Anthony, Mahgoub, Sebaey, Magdeldin, Sameh

“…The tRNA adaptation index (tAI) is a translation efficiency metric that considers weighted values ( values) for codon-tRNA wobble interaction efficiencies. The…”
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Metabolomic Profiling and In Vivo Antiepileptic Effect of Zygophyllum album Aerial Parts and Roots Crude Extracts against Pentylenetetrazole-Induced Kindling in Mice by Abdel-Hamed, Asmaa R, Wahba, Alaa S, Khodeer, Dina M, Abdel-Kader, Maged S, Badr, Jihan M, Mahgoub, Sebaey, Hal, Dina M

“…The chemical profiles of both ( ) aerial parts and roots extracts were evaluated with LC-ESI-TOF-MS/MS analysis. Twenty-four compounds were detected. Among…”
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Encephalartos villosus Lem. Displays a Strong In Vivo and In Vitro Antifungal Potential against Candida glabrata Clinical Isolates by Alqahtani, Moneerah J, Elekhnawy, Engy, Negm, Walaa A, Mahgoub, Sebaey, Hussein, Ismail A

“…Recently, has been recognized as one of the most common fungal species that is highly associated with invasive candidiasis. Its spread could be attributed to…”
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UniprotR: Retrieving and visualizing protein sequence and functional information from Universal Protein Resource (UniProt knowledgebase) by Soudy, Mohamed, Anwar, Ali Mostafa, Ahmed, Eman Ali, Osama, Aya, Ezzeldin, Shahd, Mahgoub, Sebaey, Magdeldin, Sameh

“…UniprotR is a software package designed to easily retrieve, cluster and visualize protein data from UniProt knowledgebase (UniProtKB) using R language. The…”
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Antimicrobial and antiproliferative activities of novel synthesized 6‐(quinolin‐2‐ylthio) pyridine derivatives with molecular docking study as multi‐targeted JAK2/STAT3 inhibitors by Nafie, Mohamed S., Mahgoub, Sebaey, Amer, Atef M.

“…Quinoline derivatives are attracting considerable interest due to their biological importance. In this paper, several…”
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Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition by Nafie, Mohamed S., Kishk, Safaa M., Mahgoub, Sebaey, Amer, Atef M.

“…Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer therapy. Hence, ten quinoline‐based thiazolidinone derivatives…”
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Detection of early prognostic biomarkers for metastasis of Ewing's sarcoma in pediatric patients by Ezzeldin, Shahd, Osama, Aya, Anwar, Ali Mostafa, Mahgoub, Sebaey, Ahmed, Eman A., Farid, Nesma, Zamzam, Manal, El Ghoneimy, Ahmed, Magdeldin, Sameh

“…AIMSEwing's Sarcoma is an extremely aggressive tumor in children. The disease is associated with highly metastatic rate, especially at the time of diagnosis,…”
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Pyridazine and its related compounds. Part 36. Synthesis and antimicrobial activity of some novel pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazine derivatives by Deeb, Ali, Mahgoub, Sebaey

“…Novel derivatives of pyrimidothienopyridazine were designed and synthesized through a versatile method. Some of the target compounds bearing the sulfonamide…”
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Xconnector: Retrieving and visualizing metabolites and pathways information from various database resources by Anwar, Ali Mostafa, Ahmed, Eman Ali, Soudy, Mohamed, Osama, Aya, Ezzeldin, Shahd, Tanios, Anthony, Mahgoub, Sebaey, Magdeldin, Sameh

“…Metabolomics databases contain crucial information collected from various biological systems and experiments. Developers and scientists performed massive…”
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Investigating the involvement of the NLRP3/ASC/caspase-1 and NF-κb/MAPK pathways in the pathogenesis of gouty arthritis: Insights from irradiated and non-irradiated Trifolium alexandrium L. extracts and some metabolites by Mohammed, Hala Sh, Elariny, Hemat A., Seif-Eldein, Noha A., Mahgoub, Sebaey, El-Said, Nermin T., Abu El Wafa, Salwa A., Taha, Eman FS

“…Trifolium alexandrinum L. (TA), has traditionally been used in folk medicine for its anti-inflammatory properties against hyperuricemia and gout. However, the…”
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A UPLC- MS/MS Method to Quantify β-Sitosterol and Ferulic Acid of Pygeum Africanum Extract in Bulk and Pharmaceutical Preparation by Samir, Hanan, Mahgoub, Sebaey, Badr, Jihan M, El-Gendy, Alaa, Hadad, Ghada M, Ibrahim, Elsayed A

“…Abstract This study uses a liquid chromatography-electrospray ionization–tandem mass spectrometry method to determine β-Sitosterol and Ferulic acid in Pygeum…”
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Dioon rzedowskii: An antioxidant, antibacterial and anticancer plant extract with multi-faceted effects on cell growth and molecular signaling by Negm, Walaa A., Elekhnawy, Engy, Mahgoub, Sebaey, Ibrahim, Hanaa A., Ibrahim Elberri, Aya, Abo Mansour, Hend E., Mosalam, Esraa M., Moglad, Ehssan, Alzahraa Mokhtar, Fatma

“…•The anticancer, antibacterial properties of the Dioon rzedowskii on liver and breast cancer cell lines and on solid Ehrlich carcinoma (SEC) mouse model was…”
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WITHDRAWN: Robust method for calculating the tRNA adaptation index utilizing the genetic algorithm by Mostafa Anwar, Ali, Khodary, Saif M., Soudy, Mohamed, Ahmed, Eman Ali, Osama, Aya, Ezzeldin, Shahd, Tanios, Anthony, Mahgoub, Sebaey, Magdeldin, Sameh

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