Search Results - "Maheshwari, Radha K."

A Panel of Serum MiRNA Biomarkers for the Diagnosis of Severe to Mild Traumatic Brain Injury in Humans by Bhomia, Manish, Balakathiresan, Nagaraja S., Wang, Kevin K., Papa, Linda, Maheshwari, Radha K.

“…MicroRNAs (MiRNAs) are small endogenous RNA molecules and have emerged as novel serum diagnostic biomarkers for several diseases due to their stability and…”
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Skin regenerative potentials of curcumin by Thangapazham, Rajesh L., Sharad, Shashwat, Maheshwari, Radha K.

“…Curcumin, an active constituent of the spice turmeric, is well known for its chemopreventive properties and is found to be beneficial in treating various…”
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Hemorrhage enhances cytokine, complement component 3, and caspase-3, and regulates microRNAs associated with intestinal damage after whole-body gamma-irradiation in combined injury by Kiang, Juliann G, Smith, Joan T, Anderson, Marsha N, Elliott, Thomas B, Gupta, Paridhi, Balakathiresan, Nagaraja S, Maheshwari, Radha K, Knollmann-Ritschel, Barbara

“…Hemorrhage following whole-body γ-irradiation in a combined injury (CI) model increases mortality compared to whole-body γ-irradiation alone (RI). The…”
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Identification of serum microRNA signatures for diagnosis of mild traumatic brain injury in a closed head injury model by Sharma, Anuj, Chandran, Raghavendar, Barry, Erin S, Bhomia, Manish, Hutchison, Mary Anne, Balakathiresan, Nagaraja S, Grunberg, Neil E, Maheshwari, Radha K

“…Wars in Iraq and Afghanistan have highlighted the problems of diagnosis and treatment of mild traumatic brain injury (mTBI). MTBI is a heterogeneous injury…”
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MDP: A Deinococcus Mn2+-Decapeptide Complex Protects Mice from Ionizing Radiation by Gupta, Paridhi, Gayen, Manoshi, Smith, Joan T, Gaidamakova, Elena K, Matrosova, Vera Y, Grichenko, Olga, Knollmann-Ritschel, Barbara, Daly, Michael J, Kiang, Juliann G, Maheshwari, Radha K

“…The radioprotective capacity of a rationally-designed Mn2+-decapeptide complex (MDP), based on Mn antioxidants in the bacterium Deinococcus radiodurans, was…”
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Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo by Thangapazham, Rajesh L, Singh, Anoop K, Sharma, Anuj, Warren, James, Gaddipati, Jaya P, Maheshwari, Radha K

“…Abstract Tea [ Camellia sinensis (Theaceae)] intake is second only to water in terms of worldwide popularity as a beverage. The Green tea polyphenols have been…”
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Hemorrhage Exacerbates Radiation Effects on Survival, Leukocytopenia, Thrombopenia, Erythropenia, Bone Marrow Cell Depletion and Hematopoiesis, and Inflammation-Associated microRNAs Expression in Kidney by Kiang, Juliann G, Smith, Joan T, Anderson, Marsha N, Swift, Joshua M, Christensen, Christine L, Gupta, Paridhi, Balakathiresan, Nagaraja, Maheshwari, Radha K

“…Exposure to high-dose radiation results in detrimental effects on survival. The effects of combined trauma, such as radiation in combination with hemorrhage,…”
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Differential host gene responses from infection with neurovirulent and partially-neurovirulent strains of Venezuelan equine encephalitis virus by Gupta, Paridhi, Sharma, Anuj, Han, Jing, Yang, Amy, Bhomia, Manish, Knollmann-Ritschel, Barbara, Puri, Raj K, Maheshwari, Radha K

“…Venezuelan equine encephalitis virus (VEEV) is an alphavirus in the family Togaviridae. VEEV causes a bi-phasic illness in mice where primary replication in…”
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Preserving Immunogenicity of Lethally Irradiated Viral and Bacterial Vaccine Epitopes Using a Radio- Protective Mn2+-Peptide Complex from Deinococcus by Gaidamakova, Elena K., Myles, Ian A., McDaniel, Dennis P., Fowler, Cedar J., Valdez, Patricia A., Naik, Shruti, Gayen, Manoshi, Gupta, Paridhi, Sharma, Anuj, Glass, Pamela J., Maheshwari, Radha K., Datta, Sandip K., Daly, Michael J.

“…Although pathogen inactivation by γ-radiation is an attractive approach for whole-organism vaccine development, radiation doses required to ensure sterility…”
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Green tea polyphenol and epigallocatechin gallate induce apoptosis and inhibit invasion in human breast cancer cells by Thangapazham, Rajesh L., Passi, Neena, Maheshwari, Radha K.

“…Currently, there is no effective therapy for estrogen independent breast cancer. MDA-MB-231 is an estrogen receptor negative highly invasive human breast…”
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Miltefosine inhibits Chikungunya virus replication in human primary dermal fibroblasts [version 1; peer review: 2 approved, 1 approved with reservations] by Sharma, Anuj, Bhomia, Manish, Yeh, Tze-Jou, Singh, Jay, Maheshwari, Radha K

“…Background: Chikungunya virus (CHIKV) is a re-emerging pathogen that has caused widespread outbreaks affecting millions of people around the globe. Currently,…”
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Second generation inactivated eastern equine encephalitis virus vaccine candidates protect mice against a lethal aerosol challenge by Honnold, Shelley P, Bakken, Russell R, Fisher, Diana, Lind, Cathleen M, Cohen, Jeffrey W, Eccleston, Lori T, Spurgers, Kevin B, Maheshwari, Radha K, Glass, Pamela J

“…Currently, there are no FDA-licensed vaccines or therapeutics for eastern equine encephalitis virus (EEEV) for human use. We recently developed several methods…”
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Inactivation of Chikungunya virus by 1,5 iodonapthyl azide by Sharma, Anuj, Gupta, Paridhi, Maheshwari, Radha K

“…Chikungunya virus (CHIKV) is an arthropod borne alphavirus of the family Togaviridae. CHIKV is a reemerging virus for which there is no safe prophylactic…”
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Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brain by Sharma, Anuj, Bhattacharya, Bhaskar, Puri, Raj K, Maheshwari, Radha K

“…Neurovirulent Venezuelan equine encephalitis virus (VEEV) causes lethal encephalitis in equines and is transmitted to humans by mosquitoes. VEEV is highly…”
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Role of adhesion molecules and inflammation in Venezuelan equine encephalitis virus infected mouse brain by Sharma, Anuj, Bhomia, Manish, Honnold, Shelley P, Maheshwari, Radha K

“…Neuroinvasion of Venezuelan equine encephalitis virus (VEEV) and subsequent initiation of inflammation in the brain plays a crucial role in the outcome of VEEV…”
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MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury by Balakathiresan, Nagaraja, Bhomia, Manish, Chandran, Raghavendar, Chavko, Mikulas, McCarron, Richard M, Maheshwari, Radha K

“…Blast-induced traumatic brain injury (TBI) is of significant concern in soldiers returning from the current conflicts in Iraq and Afghanistan. Incidents of TBI…”
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Multiple biological activities of curcumin: A short review by Maheshwari, Radha K., Singh, Anoop K., Gaddipati, Jaya, Srimal, Rikhab C.

“…Turmeric (Curcuma longa rhizomes), commonly used as a spice is well documented for its medicinal properties in Indian and Chinese systems of medicine. It has…”
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Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome by Thangapazham, Rajesh L., Shaheduzzaman, Syed, Kim, Kee-Hong, Passi, Neena, Tadese, Atekelt, Vahey, Maryanne, Dobi, Albert, Srivastava, Shiv, Maheshwari, Radha K.

“…Curcumin (diferuloylmethane) is the major active component of turmeric and is being actively investigated for its anti-cancer properties. To better understand…”
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Serum and amygdala microRNA signatures of posttraumatic stress: Fear correlation and biomarker potential by Balakathiresan, Nagaraja S, Chandran, Raghavendar, Bhomia, Manish, Jia, Min, Li, He, Maheshwari, Radha K

“…Abstract Exposure to acute traumatic stress can cause permanent changes in neurological circuitry and may lead to the development of an anxiety disorder known…”
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Multiple molecular targets in cancer chemoprevention by curcumin by Thangapazham, Rajesh L, Sharma, Anuj, Maheshwari, Radha K

“…Carcinogenesis encompasses 3 closely associated stages: initiation, progression, and promotion. Phytochemicals are nonnutritive components of plants that are…”
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