Search Results - "Maher, Sherif A"
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Pantoprazole Attenuates MAPK (ERK1/2, JNK, p38)–NF-κB and Apoptosis Signaling Pathways after Renal Ischemia/Reperfusion Injury in Rats
Published in International journal of molecular sciences (01-10-2021)“…Ischemia/reperfusion injury (IRI) in the kidney is the most common cause of acute renal dysfunction through different cell damage mechanisms. This study aimed…”
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Vincamine Modulates the Effect of Pantoprazole in Renal Ischemia/Reperfusion Injury by Attenuating MAPK and Apoptosis Signaling Pathways
Published in Molecules (Basel, Switzerland) (18-02-2022)“…Pantoprazole has an antioxidant function against reactive oxygen species (ROS). Vincamine, a herbal candidate, is an indole alkaloid of clinical use against…”
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3
Wound healing potential of Cystoseira/mesenchymal stem cells in immunosuppressed rats supported by overwhelming immuno-inflammatory crosstalk
Published in PloS one (04-04-2024)“…Wound healing, one of the most intricate and dynamic processes of the body, maintains skin integrity following trauma. One of the main issues that still exists…”
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The Potential of Corchorus olitorius Seeds Buccal Films for Treatment of Recurrent Minor Aphthous Ulcerations in Human Volunteers
Published in Molecules (Basel, Switzerland) (18-10-2022)“…Aphthous ulcers are very common disorders among different age groups and are very noxious and painful. The incidence of aphthous ulcer recurrence is very high…”
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5
A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis
Published in Drug delivery (01-01-2021)“…The work aimed to develop a co-loaded loratadine and sulpiride nasal nanoemulsion for allergic rhinitis management. Compatibility studies were conducted…”
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Wound Restorative Power of Halimeda macroloba / Mesenchymal Stem Cells in Immunocompromised Rats via Downregulating Inflammatory/Immune Cross Talk
Published in Marine drugs (30-05-2023)“…Impaired skin wound healing is still a major challenge, especially with immunocompromised patients who express delayed healing and are susceptible to…”
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Antioxidant and Wound Healing Potential of Vitis vinifera Seeds Supported by Phytochemical Characterization and Docking Studies
Published in Antioxidants (29-04-2022)“…This study explored the in vivo wound healing potential of Vitis vinifera seed extract using an excision wound model with focus on wound healing molecular…”
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Wound Healing and Antioxidant Capabilities of Zizyphus mauritiana Fruits: In-Vitro, In-Vivo, and Molecular Modeling Study
Published in Plants (Basel) (24-05-2022)“…LC-HRMS-assisted chemical profiling of Zizyphus mauritiana fruit extract (ZFE) led to the dereplication of 28 metabolites. Furthermore, wound healing activity…”
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Network pharmacology, molecular docking study, and in vivo validation of the wound healing activity of the Red Sea soft coral Paralemnalia thyrsoides (Ehrenberg 1834) ethanolic extract and bioactive metabolites
Published in Beni-Suef University journal of basic and applied sciences (01-12-2024)“…Background Wounds are a major health issue on a global scale, putting a great deal of financial, commercial, and social strain on healthcare organizations,…”
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Mechanistic Wound Healing and Antioxidant Potential of Moringa oleifera Seeds Extract Supported by Metabolic Profiling, In Silico Network Design, Molecular Docking, and In Vivo Studies
Published in Antioxidants (01-09-2022)“…Moringa oleifera Lam. (Moringaceae) is an adaptable plant with promising phytoconstituents, interesting medicinal uses, and nutritional importance. Chemical…”
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Antiulcer Potential of Psidium guajava Seed Extract Supported by Metabolic Profiling and Molecular Docking
Published in Antioxidants (23-06-2022)“…One of the most severe human health problems is gastric ulceration. The main aim of our study is to explore the gastroprotective effect of the Psidium guajava…”
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The Wound-Healing Potential of Olea europaea L. Cv. Arbequina Leaves Extract: An Integrated In Vitro, In Silico, and In Vivo Investigation
Published in Metabolites (25-08-2022)“…Olea europaea L. Cv. Arbequina (OEA) (Oleaceae) is an olive variety species that has received little attention. Besides our previous work for the chemical…”
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Ursolic acid inhibits NF-κB signaling and attenuates MMP-9/TIMP-1 in progressive osteoarthritis: a network pharmacology-based analysis
Published in RSC advances (06-06-2024)“…Osteoarthritis (OA) is a degenerative joint disease, characterized by infiltration of monocytes into the synovial joint which promotes inflammation, stiffness,…”
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14
Sumac liposomes/mesenchymal stem cells fight methotrexate‐induced nephrotoxicity in rats via regulating Nrf‐2/Keap‐1/HO‐1 and apoptotic signaling pathways
Published in Archiv der Pharmazie (Weinheim) (16-11-2024)“…Abstract Methotrexate (MTX) is commonly employed in cancer treatment, but its clinical use is restricted due to the MTX‐associated renal injury. This study…”
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Antiulcer secondary metabolites from Elaeocarpus grandis , family Elaeocarpaceae, supported by in silico studies
Published in RSC advances (21-09-2020)“…has a very potent analgesic effect, especially to a δ-opioid receptor, but its antiulcer activity has not yet been validated. Therefore, the present study was…”
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16
Moringa extract reverses pilocarpine-induced hippocampal sclerosis in rats with temporal lobe epilepsy
Published in Journal of functional foods (01-12-2023)“…The horseradish tree “Moringa oleifera” is the most nutritious terrestrial plant around the globe. Although native to India, its fast growth and drought…”
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Hyphaene thebaica (doum)-derived extract alleviates hyperglycemia in diabetic rats: a comprehensive in silico , in vitro and in vivo study
Published in Food & function (15-11-2021)“…In the present study, we investigated the hypoglycemic effect of different extracts ( organic and aqueous) derived from the fruits of (doum) on male…”
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Wound Restorative Power of IHalimeda macroloba/I/ Mesenchymal Stem Cells in Immunocompromised Rats via Downregulating Inflammatory/Immune Cross Talk
Published in Marine drugs (01-05-2023)“…Impaired skin wound healing is still a major challenge, especially with immunocompromised patients who express delayed healing and are susceptible to…”
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Journal Article -
19
The Potential of ICorchorus olitorius/I Seeds Buccal Films for Treatment of Recurrent Minor Aphthous Ulcerations in Human Volunteers
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Aphthous ulcers are very common disorders among different age groups and are very noxious and painful. The incidence of aphthous ulcer recurrence is very high…”
Get full text
Journal Article -
20
Antiulcer secondary metabolites from , family Elaeocarpaceae, supported by studies
Published in RSC advances (21-09-2020)“…Elaeocarpus grandis has a very potent analgesic effect, especially to a δ-opioid receptor, but its antiulcer activity has not yet been validated. Therefore,…”
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