Search Results - "Maher, Brion S"

Common liability to addiction and “gateway hypothesis”: Theoretical, empirical and evolutionary perspective by Vanyukov, Michael M, Tarter, Ralph E, Kirillova, Galina P, Kirisci, Levent, Reynolds, Maureen D, Kreek, Mary Jeanne, Conway, Kevin P, Maher, Brion S, Iacono, William G, Bierut, Laura, Neale, Michael C, Clark, Duncan B, Ridenour, Ty A

“…Abstract Background Two competing concepts address the development of involvement with psychoactive substances: the “gateway hypothesis” (GH) and common…”
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Doubt and the decision-making process in obsessive-compulsive disorder by Nestadt, Gerald, MBBCh, Kamath, Vidyulata, PhD, Maher, Brion S., PhD, Krasnow, Janice, PhD, Nestadt, Paul, MD, Wang, Ying, MS, Bakker, Arnold, PhD, Samuels, Jack, PhD

“…Abstract The diagnosis of obsessive-compulsive disorder (OCD) is based on the presence of specific symptoms and their consequence in the lives of those that…”
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Positive associations between cannabis and alcohol use polygenic risk scores and phenotypic opioid misuse among African-Americans by Rabinowitz, Jill A, Jin, Jin, Kuo, Sally I-Chun, Campos, Adrian I, Rentería, Miguel E, Huhn, Andrew S, Thrul, Johannes, Reboussin, Beth A, Benke, Kelly, Domingue, Benjamin, Ialongo, Nicholas S, Maher, Brion S, Kertes, Darlene, Troiani, Vanessa, Uhl, George

“…This study examined whether polygenic risk scores (PRS) for lifetime cannabis and alcohol use were associated with misusing opioids, and whether sex…”
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Impaired FGF signaling contributes to cleft lip and palate by Riley, Bridget M, Mansilla, M. Adela, Ma, Jinghong, Daack-Hirsch, Sandra, Maher, Brion S, Raffensperger, Lisa M, Russo, Erilynn T, Vieira, Alexandre R, Dodé, Catherine, Mohammadi, Moosa, Marazita, Mary L, Murray, Jeffrey C

“…Nonsyndromic cleft lip and palate (NS CLP) is a complex birth defect resulting from a combination of genetic and environmental factors. Several members of the…”
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Genome-wide and gene-based association studies of anxiety disorders in European and African American samples by Otowa, Takeshi, Maher, Brion S, Aggen, Steven H, McClay, Joseph L, van den Oord, Edwin J, Hettema, John M

“…Anxiety disorders (ADs) are common mental disorders caused by a combination of genetic and environmental factors. Since ADs are highly comorbid with each…”
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Adverse childhood experiences and comorbidity in a cohort of people who have injected drugs by Sosnowski, David W, Feder, Kenneth A, Astemborski, Jacquie, Genberg, Becky L, Letourneau, Elizabeth J, Musci, Rashelle J, Mojtabai, Ramin, McCall, Lisa, Hollander, Eileen, Loving, Lynnet, Maher, Brion S, Kirk, Gregory D, Mehta, Shruti H, Sun, Jing

“…Childhood adversity is associated with the onset of harmful adult substance use and related health problems, but most research on adversity has been conducted…”
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Testing gene by community disadvantage moderation of sexual health outcomes among urban women by Powell, Terrinieka W, Rabinowitz, Jill A, Kaufman, Michelle R, Milam, Adam J, Benke, Kelly, Sisto, Danielle Y, Uhl, George, Maher, Brion S, Ialongo, Nicholas S

“…We examined whether the interplay between community disadvantage and a conduct disorder polygenic risk score (CD PRS) was associated with sexual health…”
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Designing and Validating a Novel Method for Assessing Delay Discounting Associated With Health Behaviors: Ecological Momentary Assessment Study by Luken, Amanda, Rabinowitz, Jill A, Wells, Jonathan L, Sosnowski, David W, Strickland, Justin C, Thrul, Johannes, Kirk, Gregory D, Maher, Brion S

“…Delay discounting quantifies an individual's preference for smaller, short-term rewards over larger, long-term rewards and represents a transdiagnostic factor…”
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Social Competence in Parents Increases Children’s Educational Attainment: Replicable Genetically-Mediated Effects of Parenting Revealed by Non-Transmitted DNA by Bates, Timothy C., Maher, Brion S., Colodro-Conde, Lucía, Medland, Sarah E., McAloney, Kerrie, Wright, Margaret J., Hansell, Narelle K., Okbay, Aysu, Kendler, Kenneth S., Martin, Nicholas G., Gillespie, Nathan A.

“…We recently reported an association of offspring educational attainment with polygenic risk scores (PRS) computed on parent’s non-transmitted alleles for…”
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A Genome-Wide Analysis of Liberal and Conservative Political Attitudes by Hatemi, Peter K., Gillespie, Nathan A., Eaves, Lindon J., Maher, Brion S., Webb, Bradley T., Heath, Andrew C., Medland, Sarah E., Smyth, David C., Beeby, Harry N., Gordon, Scott D., Montgomery, Grant W., Zhu, Ghu, Byrne, Enda M., Martin, Nicholas G.

“…The assumption that the transmission of social behaviors and political preferences is purely cultural has been challenged repeatedly over the last 40 years by…”
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Differential expression of NPAS4 in the dorsolateral prefrontal cortex following opioid overdose by Sosnowski, David W., Jaffe, Andrew E., Tao, Ran, Deep-Soboslay, Amy, Shu, Chang, Sabunciyan, Sarven, Kleinman, Joel E., Hyde, Thomas M., Maher, Brion S.

“…•NPAS4 is differentially expressed in the DLPFC following opioid overdose.•Gene expression in response to overdose may not reflect long-term opioid use.•Human…”
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Idiopathic congenital central hypoventilation syndrome: Analysis of genes pertinent to early autonomic nervous system embryologic development and identification of mutations in PHOX2b by Weese-Mayer, Debra E., Berry-Kravis, Elizabeth M., Zhou, Lili, Maher, Brion S., Silvestri, Jean M., Curran, Mark E., Marazita, Mary L.

“…Idiopathic congenital central hypoventilation syndrome (CCHS) has been linked to autonomic nervous system dysregulation and/or dysfunction (ANSD) since it was…”
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6.55 A META-ANALYSIS OF POTENTIALLY MODIFIABLE RISK FACTORS FOR CHILDHOOD ATTENTION-DEFICIT/HYPERACTIVITY DISORDER: CHEMICAL EXPOSURES AND FACTORS RELATED TO PARENTING by Holbrook, Joseph R., PhD, Claussen, Angelika Hartl, PhD, Bitsko, Rebecca H., PhD, Mortensen, Mary E., MD, O'Masta, Brenna S., MPH, Maher, Brion S., PhD, Cerles, Audrey A., BA, McGowan, Katherine, Peacock, Georgina, MD, Rush, Margaret A., PhD

“…Objectives: Both the physical and socioemotional environment impact child development, and risk factors in each of these categories may increase risk of ADHD…”
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Variants on chromosome 4q21 near PKD2 and SIBLINGs are associated with dental caries by Eckert, Scott, Feingold, Eleanor, Cooper, Margaret, Vanyukov, Michael M, Maher, Brion S, Slayton, Rebecca L, Willing, Marcia C, Reis, Steven E, McNeil, Daniel W, Crout, Richard J, Weyant, Robert J, Levy, Steven M, Vieira, Alexandre R, Marazita, Mary L, Shaffer, John R

“…A recent genome-wide association study (GWAS) for dental caries nominated the chromosomal region 4q21 near ABCG2, PKD2 and the SIBLING (small integrin-binding…”
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Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis by Zhao, Zhongming, Webb, Bradley T, Jia, Peilin, Bigdeli, T Bernard, Maher, Brion S, van den Oord, Edwin, Bergen, Sarah E, Amdur, Richard L, O'Neill, Francis A, Walsh, Dermot, Thiselton, Dawn L, Chen, Xiangning, Pato, Carlos N, Riley, Brien P, Kendler, Kenneth S, Fanous, Ayman H

“…Integrating evidence from multiple domains is useful in prioritizing disease candidate genes for subsequent testing. We ranked all known human genes (n=3819)…”
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Prioritization and Association Analysis of Murine-Derived Candidate Genes in Anxiety-Spectrum Disorders by Hettema, John M, Webb, Bradley T, Guo, An-Yuan, Zhao, Zhongming, Maher, Brion S, Chen, Xiangning, An, Seon-Sook, Sun, Cuie, Aggen, Steven H, Kendler, Kenneth S, Kuo, Po-Hsiu, Otowa, Takeshi, Flint, Jonathan, van den Oord, Edwin J

“…Background Anxiety disorders are common psychiatric conditions that are highly comorbid with each other and related phenotypes such as depression, likely due…”
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Adolescent cannabis and tobacco use are associated with opioid use in young adulthood—12‐year longitudinal study in an urban cohort by Thrul, Johannes, Rabinowitz, Jill A., Reboussin, Beth A., Maher, Brion S., Ialongo, Nicholas S.

“…Background and aims Cannabis, tobacco and alcohol use are prevalent among youth in the United States and may be risk factors for opioid use. The current study…”
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Identification and Replication of a Combined Epigenetic and Genetic Biomarker Predicting Suicide and Suicidal Behaviors by Guintivano, Jerry, Brown, Tori, Newcomer, Alison, Jones, Marcus, Cox, Olivia, Maher, Brion S., Eaton, William W., Payne, Jennifer L., Wilcox, Holly C., Kaminsky, Zachary A.

“…Considerable research suggests that suicide involves effects of genes, the environment, and their interaction. Analysis of three independent data sets of…”
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Comprehensive gene-based association study of a chromosome 20 linked region implicates novel risk loci for depressive symptoms in psychotic illness by Bigdeli, T Bernard, Maher, Brion S, Zhao, Zhongming, Oord, Edwin J C G van den, Thiselton, Dawn L, Sun, Jingchun, Webb, Bradley T, Amdur, Richard L, Wormley, Brandon, O'Neill, Francis A, Walsh, Dermot, Riley, Brien P, Kendler, Kenneth S, Fanous, Ayman H

“…Prior genomewide scans of schizophrenia support evidence of linkage to regions of chromosome 20. However, association analyses have yet to provide support for…”
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The Nature of Nurture: Using a Virtual-Parent Design to Test Parenting Effects on Children's Educational Attainment in Genotyped Families by Bates, Timothy C., Maher, Brion S., Medland, Sarah E., McAloney, Kerrie, Wright, Margaret J., Hansell, Narelle K., Kendler, Kenneth S., Martin, Nicholas G., Gillespie, Nathan A.

“…Research on environmental and genetic pathways to complex traits such as educational attainment (EA) is confounded by uncertainty over whether correlations…”
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