Search Results - "Mahendran, Ratha"

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers by Idris, Niagara Muhammad, Gnanasammandhan, Muthu Kumara, Zhang, Jing, Ho, Paul C, Mahendran, Ratha, Zhang, Yong

“…A limitation of photodynamic therapy (PDT) is the depth of penetration of visible light needed for activation of the photosensitizers, restricting treatment to…”
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The Bladder Tumor Microenvironment Components That Modulate the Tumor and Impact Therapy by Patwardhan, Mugdha Vijay, Mahendran, Ratha

“…The tumor microenvironment (TME) is complex and involves many different cell types that seemingly work together in helping cancer cells evade immune monitoring…”
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Mesoporous-Silica-Coated Up-Conversion Fluorescent Nanoparticles for Photodynamic Therapy by Qian, Hai Sheng, Guo, Hui Chen, Ho, Paul Chi-Lui, Mahendran, Ratha, Zhang, Yong

“…Near‐infrared (NIR)‐to‐visible up‐conversion fluorescent nanoparticles have potential to be used for photodynamic therapy (PDT) in deep tissue because NIR…”
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Controllable Assembly of Upconversion Nanoparticles Enhanced Tumor Cell Penetration and Killing Efficiency by Zhang, Zhen, Rahmat, Juwita Norasmara, Mahendran, Ratha, Zhang, Yong

“…The use of upconversion nanoparticles (UCNPs) for treating deep‐seated cancers and large tumors has recently been gaining momentum. Conventional approaches for…”
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The liver–gut microbiota axis modulates hepatotoxicity of tacrine in the rat by Yip, Lian Yee, Aw, Chiu Cheong, Lee, Sze Han, Hong, Yi Shuen, Ku, Han Chen, Xu, Winston Hecheng, Chan, Jessalyn Mei Xuan, Cheong, Eleanor Jing Yi, Chng, Kern Rei, Ng, Amanda Hui Qi, Nagarajan, Niranjan, Mahendran, Ratha, Lee, Yuan Kun, Browne, Edward R., Chan, Eric Chun Yong

“…The gut microbiota possesses diverse metabolic activities, but its contribution toward heterogeneous toxicological responses is poorly understood. In this…”
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Predictive biomarkers of response to bacillus Calmette‐Guérin immunotherapy and bacillus Calmette‐Guérin failure for non‐muscle invasive bladder cancer by Wang, Ziting, So, Wei Zheng, Loh, Kep Yong, Lim, Yew Koon, Mahendran, Ratha, Wu, Qing Hui, Chiong, Edmund

“…Within the heterogeneous population of patients with bacillus Calmette‐Guérin failure, there are clear differences in prognosis and therapy with regard to the…”
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Tracking transplanted cells in live animal using upconversion fluorescent nanoparticles by Idris, Niagara Muhammad, Li, Zhengquan, Ye, Lei, Wei Sim, Eugene Kwang, Mahendran, Ratha, Ho, Paul Chi-Lui, Zhang, Yong

“…Abstract With the emergence of cell transplant as an attractive treatment modality for various diseases, there is a parallel need to track the fate of these…”
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Tryptophan–kynurenine ratio as a biomarker of bladder cancer by Lee, Sze Han, Mahendran, Ratha, Tham, Sin Mun, Thamboo, Thomas Paulraj, Chionh, Billy Jianhao, Lim, Yi Xin, Tsang, Woon Chau, Wu, Qing Hui, Chia, Jun Yang, Tay, Melissa Hui Wen, Goh, Benjamin Yen Seow, Chen, Kelven Weijing, Mallari, Jeane Zepeda, Periaswami, Revathi, Raman, Lata, Choo, Shoa Nian, Kioh, Dorinda Yan Qin, Chiong, Edmund, Esuvaranathan, Kesavan, Chan, Eric Chun Yong

“…Objectives To investigate plasma and urinary kynurenine (KYN)–tryptophan (TRP) ratios in bladder cancer, expression of indoleamine 2,3‐dioxygenase 1 (IDO1) in…”
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Gmcsf and Ifnα gene therapy improves the response to BCG immunotherapy in a murine model of bladder cancer by Tham, Sin Mun, Mahendran, Ratha, Chiong, Edmund, Wu, Qing Hui, Esuvaranathan, Kesavan

“…To develop a strategy to improve response to bacillus Calmette-Gueri (BCG) using cytokine gene therapy ( + ). MB49-PSA tumor-bearing C57BL/6N mice were…”
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Urinary Metabotyping of Bladder Cancer Using Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry by Pasikanti, Kishore Kumar, Esuvaranathan, Kesavan, Hong, Yanjun, Ho, Paul C, Mahendran, Ratha, Raman Nee Mani, Lata, Chiong, Edmund, Chan, Eric Chun Yong

“…Cystoscopy is the gold standard clinical diagnosis of human bladder cancer (BC). As cystoscopy is expensive and invasive, it compromises patients’ compliance…”
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Glutathione-S-Transferase Theta 2 (GSTT2) Modulates the Response to Bacillus Calmette-Guérin Immunotherapy in Bladder Cancer Patients by Rahmat, Juwita N, Tham, Sin Mun, Ong, Ting Li, Lim, Yew Koon, Patwardhan, Mugdha Vijay, Nee Mani, Lata Raman, Kamaraj, Revathi, Chan, Yiong Huak, Chong, Tsung Wen, Chiong, Edmund, Esuvaranathan, Kesavan, Mahendran, Ratha

“…Glutathione-S-transferases (GST) enzymes detoxify xenobiotics and are implicated in response to anticancer therapy. This study evaluated the association of GST…”
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Lactobacillus rhamnosus GG induces tumor regression in mice bearing orthotopic bladder tumors by Seow, Shih Wee, Cai, Shirong, Rahmat, Juwita N., Bay, Boon Huat, Lee, Yuan Kun, Chan, Yiong Huak, Mahendran, Ratha

“…(Cancer Sci 2010; 101: 751–758) The present gold standard for bladder cancer is Mycobacterium bovis, Bacillus Calmette Guerin (BCG) immunotherapy. But it has a…”
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Detection of Clinical Mesenchymal Cancer Cells from Bladder Wash Urine for Real-Time Detection and Prognosis by Khoo, Bee Luan, Bouquerel, Charlotte, Durai, Pradeep, Anil, Sarannya, Goh, Benjamin, Wu, Bingcheng, Raman, Lata, Mahendran, Ratha, Thamboo, Thomas, Chiong, Edmund, Lim, Chwee Teck

“…Bladder cancer (BC) is a disease that requires lifelong surveillance due to its high recurrence rate. An efficient method for the non-invasive rapid monitoring…”
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Wirelessly Activated Nanotherapeutics for In Vivo Programmable Photodynamic‐Chemotherapy of Orthotopic Bladder Cancer by Sun, Bowen, Bte Rahmat, Juwita Norasmara, Kim, Han Joon, Mahendran, Ratha, Esuvaranathan, Kesavan, Chiong, Edmund, Ho, John S., Neoh, Koon Gee, Zhang, Yong

“…Photochemical internalization (PCI) is a promising intervention using photodynamic therapy (PDT) to enhance the activity of chemotherapeutic drugs. However,…”
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Combination Bacillus Calmette–Guérin and indoleamine 2,3‐dioxygenase 1 inhibitor therapy of murine orthotopic bladder cancer by Lee, Sze Han, Mahendran, Ratha, Tham, Sin Mun, Thamboo, Thomas Paulraj, Kioh, Dorinda Yan Qin, Tang, Lloyd Wei Tat, Chiong, Edmund, Esuvaranathan, Kesavan, Chan, Eric Chun Yong

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Mindfulness Awareness Practice (MAP) to Prevent Dementia in Older Adults with Mild Cognitive Impairment: Protocol of a Randomized Controlled Trial and Implementation Outcomes by Ng, Ted Kheng Siang, Feng, Lei, Fam, Johnson, Rawtaer, Iris, Kumar, Alan Prem, Rane, Grishma, Cheah, Irwin Kee-Mun, Mahendran, Ratha, Lee, Yuan Kun, Tan, Ene Choo, Goh, Lee Gan, Kua, Ee Heok, Mahendran, Rathi

“…With an aging population, developing non-pharmacological interventions (NPIs) to delay dementia has become critical. Apart from cognitive decline, dementia is…”
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Lactobacillus rhamnosus GG Activation of Dendritic Cells and Neutrophils Depends on the Dose and Time of Exposure by Mahendran, Ratha, Bay, Boon Huat, Tham, Sin Mun, Rahmat, Juwita N., Kandasamy, Matheswaran, Cai, Shirong, Lee, Yuan Kun

“…This study evaluates the ability of Lactobacillus rhamnosus GG (LGG) to activate DC and neutrophils and modulate T cell activation and the impact of bacterial…”
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Intravesical High Dose BCG Tokyo and Low Dose BCG Tokyo with GMCSF+IFN α Induce Systemic Immunity in a Murine Orthotopic Bladder Cancer Model by Tham, Sin Mun, Rahmat, Juwita N, Chiong, Edmund, Wu, Qinghui, Esuvaranathan, Kesavan, Mahendran, Ratha

“…This study evaluates a short therapy schedule for bladder cancer using BCG Tokyo. BCG Tokyo was evaluated in vitro using bone marrow derived dendritic cells,…”
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NRAMP1 and hGPX1 Gene Polymorphism and Response to Bacillus Calmette-Guérin Therapy for Bladder Cancer by Chiong, Edmund, Kesavan, Arshvin, Mahendran, Ratha, Chan, Yiong Huak, Sng, Jen Hwei, Lim, Yew Koon, Kamaraj, Revathi, Tan, Theresa M.C, Esuvaranathan, Kesavan

“…Abstract Background The natural resistance-associated macrophage protein 1 ( NRAMP1 ) gene is associated with susceptibility to Mycobacterium tuberculosis in…”
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Live and lyophilized Lactobacillus species elicit differential immunomodulatory effects on immune cells by Cai, Shirong, Bay, Boon Huat, Lee, Yuan Kun, Lu, Jinhua, Mahendran, Ratha

“…To study the mechanism of action of the lactobacilli, splenocytes were incubated with lactobacilli. We compared the ability of live and lyophilized…”
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