Search Results - "Mahelona, Ryan D."

Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR) Selective Agonists: Novel Analogues of 4‑[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and (E)‑3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic Acid (CD3254) by Jurutka, Peter W, Kaneko, Ichiro, Yang, Joanna, Bhogal, Jaskaran S, Swierski, Johnathon C, Tabacaru, Christa R, Montano, Luis A, Huynh, Chanh C, Jama, Rabia A, Mahelona, Ryan D, Sarnowski, Joseph T, Marcus, Lisa M, Quezada, Alexis, Lemming, Brittney, Tedesco, Maria A, Fischer, Audra J, Mohamed, Said A, Ziller, Joseph W, Ma, Ning, Gray, Geoffrey M, van der Vaart, Arjan, Marshall, Pamela A, Wagner, Carl E

“…Three unreported analogues of 4-[1-(3,5,5,8,8-pentamethyl-5-6-7-8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (1), otherwise known as bexarotene, as well as…”
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Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence by Yadlapalli, Jai Shankar K., Bommagani, Shoban Babu, Mahelona, Ryan D., Wan, Anqi, Gannon, Brenda M., Penthala, Narsimha R., Dobretsov, Maxim, Crooks, Peter A., Fantegrossi, William E.

“…Morphine‐6‐O‐sulfate (M6S) is as a mixed‐action mu/delta (μ/δ) opioid receptor agonist with high potency and analgesic efficacy. These studies used assays of…”
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