Search Results - "Mahdi, Wael A."

Application of quality-by-design for adopting an environmentally green fluorogenic determination of benoxinate hydrochloride in eye drops and artificial aqueous humour by El Hamd, Mohamed A., El-Maghrabey, Mahmoud, Magdy, Galal, Mahdi, Wael A., Alshehri, Sultan, Bass, Amr K. A., Batakoushy, Hany A.

“…Herein, a sensitive and selective spectrofluorimetric method has been developed for the determination of the ocular local anesthetic benoxinate hydrochloride…”
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Neuroprotectant Effects of Hibiscetin in 3-Nitropropionic Acid-Induced Huntington's Disease via Subsiding Oxidative Stress and Modulating Monoamine Neurotransmitters in Rats Brain by Mahdi, Wael A, AlGhamdi, Shareefa A, Alghamdi, Amira M, Imam, Syed Sarim, Alshehri, Sultan, Almaniea, Mohammad A, Hajjar, Baraa Mohammed, Al-Abbasi, Fahad A, Sayyed, Nadeem, Kazmi, Imran

“…Previously reported data suggest that hibiscetin, isolated from , contains delphinidin-3-sambubioside and cyanidin-3-sambubioside including anthocyanidins and…”
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Solubilization and Thermodynamic Analysis of Isotretinoin in Eleven Different Green Solvents at Different Temperatures by Shakeel, Faiyaz, Haq, Nazrul, Mahdi, Wael A, Alsarra, Ibrahim A, Alshehri, Sultan, Alenazi, Miteb, Alwhaibi, Abdulrahman

“…The solubilization and thermodynamic analysis of isotretinoin (ITN) in eleven distinct green solvents, such as water, methyl alcohol (MeOH), ethyl alcohol…”
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Recent Progress in Lipid Nanoparticles for Cancer Theranostics: Opportunity and Challenges by Bukhari, Sarah I, Imam, Syed Sarim, Ahmad, Mohammad Zaki, Vuddanda, Parameswara Rao, Alshehri, Sultan, Mahdi, Wael A, Ahmad, Javed

“…Cancer is one of the major leading causes of mortality in the world. The implication of nanotherapeutics in cancer has garnered splendid attention owing to…”
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Formulation of Chitosan-Coated Apigenin Bilosomes: In Vitro Characterization, Antimicrobial and Cytotoxicity Assessment by Imam, Syed Sarim, Alshehri, Sultan, Altamimi, Mohammad A, Almalki, Raed Khalid Hassan, Hussain, Afzal, Bukhari, Sarah I, Mahdi, Wael A, Qamar, Wajhul

“…We prepared apigenin (APG)-loaded bilosomes (BLs) and evaluated them for vesicle size, zeta-potential and encapsulation efficiency. The formulations were…”
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Formulation and Optimization of Butenafine-Loaded Topical Nano Lipid Carrier-Based Gel: Characterization, Irritation Study, and Anti-Fungal Activity by Mahdi, Wael A, Bukhari, Sarah I, Imam, Syed Sarim, Alshehri, Sultan, Zafar, Ameeduzzafar, Yasir, Mohd

“…The present study aims to prepare and optimize butenafine hydrochloride NLCs formulation using solid and liquid lipid. The optimized selected BF-NLCopt was…”
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Solubility and Thermodynamic Properties of Febuxostat in Various (PEG 400 + Water) Mixtures by Alghaith, Adel F., Mahdi, Wael A., Haq, Nazrul, Alshehri, Sultan, Shakeel, Faiyaz

“…The solubility of the poorly soluble medicine febuxostat (FXT) (3) in various {polyethylene glycol 400 (PEG 400) (1) + water (H2O) (2)} mixtures has been…”
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Two Versatile Pencil Graphite-Polymer Sensor Electrodes Coupled with Potentiometry and Potentiometric Titration Methods: Profiling Determinations of Vitamin V in Tablets and Urine Samples by Hassan, Abeer M E, El Hamd, Mohamed A, El-Maghrabey, Mahmoud H, Mahdi, Wael A, Alshehri, Sultan, Batakoushy, Hany A

“…Herein, we developed a new pencil graphite ion-selective electrode strategy for the broadly used erectile dysfunction medication, sildenafil citrate (SC,…”
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Identification of Potential Antitubulin Agents with Anticancer Assets from a Series of Imidazo[1,2- a ]quinoxaline Derivatives: In Silico and In Vitro Approaches by Goel, Kapil Kumar, Hussain, Afzal, Altamimi, Mohammad A, Rajput, Satyendra Kumar, Sharma, Prince Prashant, Kharb, Rajeev, Mahdi, Wael A, Imam, Syed Sarim, Alshehri, Sultan, Alnemer, Osamah Abdulrahman, Chaudhary, Anu

“…Computer-aided drug design is a powerful and promising tool for drug design and development, with a reduced cost and time. In the current study, we rationally…”
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Formulation of silymarin surface modified vesicles: In vitro characterization to cell viability assessment by Imam, Syed Sarim, Alshammari, Sultan Owaid, Alshehri, Sultan, Mahdi, Wael A., Al-Agamy, Mohamed H.

“…Silymarin (SLR) is a poorly water-soluble bioactive compound with a wide range of therapeutic activities. Nanosized silymarin vesicles (F1–F6) were prepared by…”
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Citrate-Capped AuNP Fabrication, Characterization and Comparison with Commercially Produced Nanoparticles by Memon, Abdul, Channa, Iftikhar, Shaikh, Asif, Ahmad, Jabran, Soomro, Abdul, Giwa, Abdulmoseen, Baig, Zenab, Mahdi, Wael, Alshehri, Sultan

“…Gold nanoparticles (AuNPs) were synthesized using citrate reduction, also known as the Turkevich method. The AuNPs were compared with the commercially…”
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Phytoconstituents of Butterbur (P. japonicus), their metabolic pathway and ability to modulate bone morphogenic protein (BMP) signaling by Belal, Amany, Ibrahim, Mona H., Mahdi, Wael A., Alshehri, Sultan, Ebrahim, Hasnaa Ali, Ghoneim, Mohammed M., El-Sherbiny, Mohamed, Mehany, Ahmed B. M., Ghamry, Heba I.

“…A library of natural sesquiterpene and phenolic compounds from Petasites japonicus are being investigated through different computational techniques to study…”
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Novel Natrosol/Pectin-co-poly (acrylate) based pH-responsive polymeric carrier system for controlled delivery of Tapentadol Hydrochloride by Zafar, Nadiah, Mahmood, Asif, Ilyas, Sehar, Ijaz, Hira, Muhammad Sarfraz, Rai, Mahdi, Wael A., Salem-Bekhit, Mounir M., Ibrahim, Mohamed A., Benguerba, Yacine, Ernst, Barbara

“…This study aimed to create a controlled delivery system for Tapentadol Hydrochloride by developing interpenetrating networks (IPNs) of Natrosol-Pectin…”
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Formulation of Multicomponent Chrysin-Hydroxy Propyl β Cyclodextrin-Poloxamer Inclusion Complex Using Spray Dry Method: Physicochemical Characterization to Cell Viability Assessment by Imam, Syed Sarim, Alshehri, Sultan, Mahdi, Wael A, Alotaibi, Ahmed M, Alhwaifi, Moath H, Hussain, Afzal, Altamimi, Mohammad A, Qamar, Wajhul

“…The work aimed to enhance chrysin (CHR) water solubility, dissolution, and in vitro antibacterial as well as cell viability. Chrysin binary, as well as ternary…”
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Optimisation of a Greener-Approach for the Synthesis of Cyclodextrin-Based Nanosponges for the Solubility Enhancement of Domperidone, a BCS Class II Drug by Vij, Mohit, Dand, Neha, Kumar, Lalit, Wadhwa, Pankaj, Wani, Shahid Ud Din, Mahdi, Wael A, Alshehri, Sultan, Alam, Prawez, Shakeel, Faiyaz

“…BCS class II molecules suffer from low oral bioavailability because of their poor permeability and sub-optimal aqueous solubility. One of the approaches to…”
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Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates by Badr-Eldin, Shaimaa M, Alhakamy, Nabil A, Fahmy, Usama A, Ahmed, Osama A A, Asfour, Hani Z, Althagafi, Abdulhamid A, Aldawsari, Hibah M, Rizg, Waleed Y, Mahdi, Wael A, Alghaith, Adel F, Alshehri, Sultan, Caraci, Filippo, Caruso, Giuseppe

“…Fluvastatin (FLV) is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor often used to lower total and low-density lipoprotein (LDL) cholesterol…”
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GC-MS Analysis, Phytochemical Screening, and Antibacterial Activity of Cerana indica Propolis from Kashmir Region by Mohiuddin, Ishfaq, Kumar, T. Ramesh, Zargar, Mohammed Iqbal, Wani, Shahid Ud Din, Mahdi, Wael A., Alshehri, Sultan, Alam, Prawez, Shakeel, Faiyaz

“…Propolis is a resinous compound produced by honey bees. It contains bioactive molecules that possess a wide range of biological functions. The chemical…”
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Development, Optimization and Evaluation of 2-Methoxy-Estradiol Loaded Nanocarrier for Prostate Cancer by Alhakamy, Nabil A., Ahmed, Osama A., Fahmy, Usama A., Asfour, Hani Z., Alghaith, Adel F., Mahdi, Wael A., Alshehri, Sultan, Md, Shadab

“…The therapeutic efficacy of antineoplastic agents possessing a selective target to the nucleus of the cancer cells could be enhanced through novel formulation…”
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A Greener Stability-Indicating High-Performance Thin-Layer Chromatography Approach for the Estimation of Topiramate by Alqarni, Mohammed H, Shakeel, Faiyaz, Mahdi, Wael A, Foudah, Ahmed I, Aljarba, Tariq M, Alshehri, Sultan, Ghoneim, Mohammed M, Alam, Prawez

“…Despite various reported analytical methods for topiramate (TPM) analysis, greener analytical approaches are scarce in literature. As a consequence, the…”
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A Novel Approach for the Availability and Ocular Delivery of Tenoxicam Potassium: Synthesis, Characterization, and In Vivo Application by Osman, Shaaban K., Yassin, Taher M., Mohammed, Ahmed M., Alfayomy, Abdallah M., Abdellatif, Ahmed A., Mahdi, Wael A., Alshehri, Sultan, Hamd, Mohamed A. El, Sarhan, Hatem, Ibrahim, Mohammed A.

“…Tenoxicam (TX) is a non-steroidal anti-inflammatory agent that can be used to control pain in various ophthalmic lesions like cataracts, refractive surgery,…”
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