Search Results - "Mahdavi, Alborz"
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Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-2014)“…Protein-based hydrogels have emerged as promising alternatives to synthetic hydrogels for biomedical applications, owing to the precise control of structure…”
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Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2013)“…The study of hematopoietic colony-forming units using semisolid culture media has greatly advanced the knowledge of hematopoiesis. Here we report that similar…”
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3
Outcomes of the infantile cataract surgery: case series with a 5-year follow-up
Published in International ophthalmology (01-02-2022)“…Purpose To present the 5-year outcomes obtained from the infantile cataract surgery in pediatric population. Methods Medical records of all patients with…”
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4
Association of central serous chorioretinopathy with single nucleotide polymorphisms in complement factor H gene in Iranian population
Published in Eye (London) (01-05-2022)“…Objectives To investigate the association of two different single nucleotide polymorphisms (SNPs) in the complement factor H (CFH) gene with central serous…”
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5
Identification of secreted bacterial proteins by noncanonical amino acid tagging
Published in Proceedings of the National Academy of Sciences - PNAS (07-01-2014)“…Pathogenic microbes have evolved complex secretion systems to deliver virulence factors into host cells. Identification of these factors is critical for…”
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6
biodegradable and biocompatible gecko-inspired tissue adhesive
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2008)“…There is a significant medical need for tough biodegradable polymer adhesives that can adapt to or recover from various mechanical deformations while remaining…”
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7
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells
Published in Lab on a chip (2007)“…Directed differentiation of embryonic stem (ES) cells is useful for creating models of human disease and could potentially generate a wide array of functional…”
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Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens
Published in PloS one (30-07-2009)“…In vivo, stem cell fate is regulated by local microenvironmental parameters. Governing parameters in this stem cell niche include soluble factors,…”
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LIF‐mediated control of embryonic stem cell self‐renewal emerges due to an autoregulatory loop
Published in The FASEB journal (01-07-2007)“…Stem cells convert graded stimuli into all‐or‐nothing cell‐fate responses. We investigated how embryonic stem cells (ESCs) convert leukemia inhibitory factor…”
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10
Predictive ability of six obesity measures to identify 7-year fatal and non-fatal cardiovascular events: A population-based cohort study
Published in International journal of cardiology. Cardiovascular risk and prevention (01-09-2022)“…Globally, most people die from cardiovascular diseases. We aimed to compare predictive ability of six obesity indices, including body mass index, waist…”
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Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control
Published in PLoS computational biology (01-07-2007)“…Directing stem cell fate requires knowledge of how signaling networks integrate temporally and spatially segregated stimuli. We developed and validated a…”
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12
Cell-selective metabolic labeling of proteins
Published in Nature chemical biology (09-08-2009)Get full text
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13
A magnetic cell-based sensor
Published in Lab on a chip (07-11-2012)“…Cell-based sensing represents a new paradigm for performing direct and accurate detection of cell- or tissue-specific responses by incorporating living cells…”
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Journal Article -
14
Cleavable Biotin Probes for Labeling of Biomolecules via Azide−Alkyne Cycloaddition
Published in Journal of the American Chemical Society (29-12-2010)“…The azide−alkyne cycloaddition provides a powerful tool for bio-orthogonal labeling of proteins, nucleic acids, glycans, and lipids. In some labeling…”
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15
Cell-selective metabolic labeling of proteins
Published in Nature chemical biology (01-10-2009)“…Metabolic labeling of proteins with the methionine surrogate azidonorleucine can be targeted exclusively to specified cells through expression of a mutant…”
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Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro
Published in Stem cells and development (01-09-2015)“…Postnatal pancreas is a potential source for progenitor cells to generate endocrine β-cells for treating type 1 diabetes. However, it remains unclear whether…”
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A Genetically Encoded AND Gate for Cell-Targeted Metabolic Labeling of Proteins
Published in Journal of the American Chemical Society (27-02-2013)“…We describe a genetic AND gate for cell-targeted metabolic labeling and proteomic analysis in complex cellular systems. The centerpiece of the AND gate is a…”
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18
Synthetic biology tools for targeted incorporation of non-canonical amino acids into cellular proteins
Published 01-01-2015“…Proteins mediate many essential functions in cells, and methods to profile cellular proteins are of great interest for biological discovery. Whereas all of the…”
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Dissertation -
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Engineered Aminoacyl-tRNA Synthetase for Cell-Selective Analysis of Mammalian Protein Synthesis
Published in Journal of the American Chemical Society (06-04-2016)“…Methods for cell-selective analysis of proteome dynamics will facilitate studies of biological processes in multicellular organisms. Here we describe a mutant…”
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Journal Article -
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Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas
Published in Stem cell research (01-01-2016)“…Progenitor cells in the adult pancreas are potential sources of endocrine beta cells for treating type 1 diabetes. Previously, we identified tri-potent…”
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