Search Results - "Mahato, Arun Kumar"

Adult-onset Still’s Disease: A Case Report by Karki, Bikash, K C, Niranjan, Kumar Mahato, Arun, Kandel, Saksham, Acharya, Prakash

“…Pyrexia of unknown origin refers to a fever of over 38.3°C on multiple occasions for at least three weeks without a known aetiology, even after a week of…”
Get full text

RET Receptor Tyrosine Kinase: Role in Neurodegeneration, Obesity, and Cancer by Mahato, Arun Kumar, Sidorova, Yulia A

“…Rearranged during transfection (RET) is the tyrosine kinase receptor that under normal circumstances interacts with ligand at the cell surface and mediates…”
Get full text

Preparation of luliconazole nanocrystals loaded hydrogel for improvement of dissolution and antifungal activity by Kumar, Manish, Shanthi, Nithya, Mahato, Arun Kumar, Soni, Shashank, Rajnikanth, P.S.

“…Superficial fungal infection in immunocompromised patients can lead to many disorders and complications. Currently, new topical treatment options are…”
Get full text

Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis by Guo, Xuanming, Asthana, Pallavi, Zhai, Lixiang, Cheng, Ka Wing, Gurung, Susma, Huang, Jiangang, Wu, Jiayan, Zhang, Yijing, Mahato, Arun Kumar, Saarma, Mart, Ustav, Mart, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Xu, Pingyi, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier

“…Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an…”
Get full text

Glial cell line–derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo by Mahato, Arun Kumar, Kopra, Jaakko, Renko, Juho‐Matti, Visnapuu, Tanel, Korhonen, Ilari, Pulkkinen, Nita, Bespalov, Maxim M., Domanskyi, Andrii, Ronken, Eric, Piepponen, T. Petteri, Voutilainen, Merja H., Tuominen, Raimo K., Karelson, Mati, Sidorova, Yulia A., Saarma, Mart

“…Background Motor symptoms of Parkinson's disease (PD) are caused by degeneration and progressive loss of nigrostriatal dopamine neurons. Currently, no cure for…”
Get full text

Typhoid Fever among Patients Diagnosed with Dengue in a Tertiary Care Centre: A Descriptive Cross-sectional Study by Mahato, Arun Kumar, Shrestha, Nischal, Gharti, Sakar Babu, Shah, Madhu

“…Dengue and typhoid fever are different entities with overlapping signs and symptoms which are indistinguishable and there have been few reports of…”
Get full text

Prevalence of Dyslipidemia in Patients with Acute Coronary Syndrome Admitted at Tertiary Care Hospital in Nepal: A Descriptive Cross-sectional Study by Dhungana, Sahadeb Prasad, Mahato, Arun Kumar, Ghimire, Rinku, Shreewastav, Rupesh Kumar

“…Dyslipidemia is one of the major risk factors for acute coronary syndrome. Dyslipidemia with an increase in total cholesterol, low-density lipoprotein…”
Get full text

Body weight regulation via MT1-MMP-mediated cleavage of GFRAL by Chow, Chi Fung Willis, Guo, Xuanming, Asthana, Pallavi, Zhang, Shuo, Wong, Sheung Kin Ken, Fallah, Samane, Che, Sijia, Gurung, Susma, Wang, Zening, Lee, Ki Baek, Ge, Xin, Yuan, Shiyang, Xu, Haoyu, Ip, Jacque Pak Kan, Jiang, Zhixin, Zhai, Lixiang, Wu, Jiayan, Zhang, Yijing, Mahato, Arun Kumar, Saarma, Mart, Lin, Cheng Yuan, Kwan, Hiu Yee, Huang, Tao, Lyu, Aiping, Zhou, Zhongjun, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier

“…GDNF-family receptor a-like (GFRAL) has been identified as the cognate receptor of growth/differentiation factor 15 (GDF15/MIC-1), considered a key signaling…”
Get full text

Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro by Saarenpää, Tuulia, Kogan, Konstantin, Sidorova, Yulia, Mahato, Arun Kumar, Tascón, Igor, Kaljunen, Heidi, Yu, Liying, Kallijärvi, Jukka, Jurvansuu, Jaana, Saarma, Mart, Goldman, Adrian

“…Glial cell line-derived neurotrophic factor (GDNF) is a ligand that activates, through co-receptor GDNF family receptor alpha-1 (GFRα1) and receptor tyrosine…”
Get full text

Studies on synthesis and characteristics of zeolite prepared from Indian fly ash by Prasad, Bably, Maity, Sudip, Sangita, Kumari, Mahato, Arun Kumar, Mortimer, Robert J.G

“…In the present study, samples of coal fly ash were obtained from seven major Indian thermal power plants. These samples were transformed into fly ash zeolite…”
Get full text

Glial cell line-derived neurotrophic factors (GFLs) and small molecules targeting RET receptor for the treatment of pain and Parkinson’s disease by Mahato, Arun Kumar, Sidorova, Yulia A.

“…Rearranged during transfection (RET), in complex with glial cell line-derived (GDNF) family receptor alpha (GFRα), is the canonical signaling receptor for GDNF…”
Get full text

Glial cell line-derived neurotrophic factors by Mahato, Arun Kumar, Sidorova, Yulia A

“…Rearranged during transfection (RET), in complex with glial cell line-derived (GDNF) family receptor alpha (GFR[alpha]), is the canonical signaling receptor…”
Get full text

Study of Gastro-Oesophageal Reflux Disease among Patients with Type 2 Diabetes Mellitus presenting to Medicine Department at a Tertiary Care Hospital: A Descriptive Cross-sectional Study by Mahato, Arun Kumar, Shah, Madhu, Shrestha, Nischal

“…Introduction: Gastro-oesophageal reflux disease is a chronic condition in which stomach contents regurgitates up into oesophagus causing symptoms like acidic…”
Get full text

Oral delivery of butoconazole nitrate nanoparticles for systemic treatment of chronic paracoccidioidomycosis: A future aspect by Tasleem, Shanthi, Nithya, Mahato, Arun Kumar, Bahuguna, Richa

“…The purpose of this review is to emphasize the importance of nanotechnology in the field of drug delivery systems to contradict the complications associated…”
Get full text

Biological Activity In Vitro, Absorption, BBB Penetration, and Tolerability of Nanoformulation of BT44:RET Agonist with Disease-Modifying Potential for the Treatment of Neurodegeneration by Haider, Malik Salman, Mahato, Arun Kumar, Kotliarova, Anastasiia, Forster, Stefan, Böttcher, Bettina, Stahlhut, Philipp, Sidorova, Yulia, Luxenhofer, Robert

“…BT44 is a novel, second-generation glial cell line-derived neurotropic factor mimetic with improved biological activity and is a lead compound for the…”
Get full text

Synthesis and characterization of dimeric μ‐oxidovanadium complexes as the functional model of vanadium bromoperoxidase by Maurya, Abhishek, Mahato, Arun Kumar, Chaudhary, Nikita, Kesharwani, Neha, Kachhap, Payal, Mishra, Vivek Kumar, Haldar, Chanchal

“…Two vanadium (IV) complexes [VIVO(Haeae‐sal)(MeOH)]+ (1) and [VIVO(Haeae‐hyap)(MeOH)]+ (2) were prepared by reacting [VO(acac)2] with ligands [H2aeae‐sal] (I)…”
Get full text

Therapeutic Potential of Cornus Genus: Navigating Phytochemistry, Pharmacology, Clinical Studies, and Advanced Delivery Approaches by Badoni, Subhashini, Rawat, Deepshikha, Mahato, Arun Kumar, Jangwan, Nitish Singh, Ashraf, Ghulam Md, Alexiou, Athanasios, Tayeb, Haythum O., Alghamdi, Badrah S., Papadakis, Marios, Singh, Mamta F.

“…The genus Cornus (Cornaceae) plants are widely distributed in Europe, southwest Asia, North America, and the mountains of Central America, South America, and…”
Get full text

Significance of Triazole in Medicinal Chemistry: Advancement in Drug Design, Reward and Biological Activity by Ajmal, Mohammad, Mahato, Arun Kumar, Khan, Mausin, Rawat, Shivani, Husain, Asif, Almalki, Emad Bakheet, Alzahrani, Mohammed Ahmed, Haque, Anzarul, Hakme, Mohammed Japer Mohammed, Albalawi, Ahmed Suleman, Rashid, Mohammad

“…One of the triazole tautomers, 1,2,4‐triazole derivatives, has a wide range of biological activities that suggest its potential therapeutic utility in…”
Get full text

Comparative performance of electric vehicles using evaluation of mixed data by Das, Manik Chandra, Pandey, Abanish, Mahato, Arun Kumar, Singh, Rajnish Kumar

“…The electric vehicle (EV) technology has been getting momentum due to rapid depletion of fossil fuels and also in taking care of environment. Many…”
Get full text

Zebrafish GDNF and its co-receptor GFR[alpha]1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro by Saarenpää, Tuulia, Kogan, Konstantin, Sidorova, Yulia, Mahato, Arun Kumar, Tascón, Igor, Kaljunen, Heidi, Yu, Liying, Kallijärvi, Jukka, Jurvansuu, Jaana, Saarma, Mart, Goldman, Adrian

“…Glial cell line-derived neurotrophic factor (GDNF) is a ligand that activates, through co-receptor GDNF family receptor alpha-1 (GFR[alpha]1) and receptor…”
Get full text