Search Results - "Mahapatra, Nitish"

Renalase: a novel regulator of cardiometabolic and renal diseases by Vijayakumar, Anupama, Mahapatra, Nitish R

“…Renalase is a ~38 kDa flavin-adenine dinucleotide (FAD) domain-containing protein that can function as a cytokine and an anomerase. It is emerging as a novel…”
Get full text

Metallic micro-ring device for highly efficient large cargo delivery in mammalian cells using infrared light pulses by Shinde, Ashwini, Shinde, Pallavi, Kar, Srabani, Illath, Kavitha, Dey, Souvik, Mahapatra, Nitish R, Nagai, Moeto, Santra, Tuhin Subhra

“…Uniform transfection of biomolecules into live cells with high delivery efficiency and cell viability is an immensely important area of biological research and…”
Get more information

Key regulatory miRNAs in lipid homeostasis: Implications for cardiometabolic diseases and development of novel therapeutics by Khan, Abrar A., Gupta, Vinayak, Mahapatra, Nitish R.

“…•Dysregulation of lipid metabolism is associated with cardiometabolic diseases.•microRNAs have emerged as crucial regulators of lipid metabolism.•We highlight…”
Get full text

Engineering the Nonmorphing Point of Actuation for Controlled Drug Release by Hydrogel Bilayer across the pH Spectrum by Kumar, Amit, Rajamanickam, Raja, Hazra, Joyita, Mahapatra, Nitish R., Ghosh, Pijush

“…Hydrogel-based pH-responsive bilayer actuators exhibit bidirectional actuation due to the differences in the concentration gradient developed across the…”
Get full text

Emerging role of heat shock proteins in cardiovascular diseases by Hazra, Joyita, Vijayakumar, Anupama, Mahapatra, Nitish R

“…Heat Shock Proteins (HSPs) are evolutionarily conserved proteins from prokaryotes to eukaryotes. They are ubiquitous proteins involved in key physiological and…”
Get full text

Chromogranin A and its derived peptides: potential regulators of cholesterol homeostasis by Iyer, Dhanya R., Venkatraman, Janani, Tanguy, Emeline, Vitale, Nicolas, Mahapatra, Nitish R.

“…Chromogranin A (CHGA), a member of the granin family of proteins, has been an attractive therapeutic target and candidate biomarker for several cardiovascular,…”
Get full text

Correction: Chromogranin A and its derived peptides: potential regulators of cholesterol homeostasis by Iyer, Dhanya R., Venkatraman, Janani, Tanguy, Emeline, Vitale, Nicolas, Mahapatra, Nitish R.

Get full text

Efficient reduction of the scrolling of Descemet membrane endothelial keratoplasty grafts by engineering the medium by Gupta, Nidhi, Kumar, Amit, Vaddavalli, Pravin K, Mahapatra, Nitish R., Varshney, Akhil, Ghosh, Pijush

“…The Descemet Membrane Endothelial Keratoplasty (DMEK) procedure for corneal transplantation is challenging due to the need to unscroll the donor graft within…”
Get full text

Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB by Arkat, Silpa, Poovitha, Sundar, Vijayakumar, Anupama, Dhat, Rohini, Sitasawad, Sandhya L, Mahapatra, Nitish R

“…Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites. Altered levels…”
Get more information

MicroRNA 27a Is a Key Modulator of Cholesterol Biosynthesis by Khan, Abrar A., Agarwal, Heena, Reddy, S. Santosh, Arige, Vikas, Natarajan, Bhargavi, Gupta, Vinayak, Kalyani, Ananthamohan, Barthwal, Manoj K., Mahapatra, Nitish R.

“…Hypercholesterolemia is a strong predictor of cardiovascular diseases. The 3-hydroxy-3-methylglutaryl coenzyme A reductase gene (Hmgcr) coding for the…”
Get full text

SARS-CoV-2 infection and its effects on the endocrine system by Steenblock, Charlotte, Toepfner, Nicole, Beuschlein, Felix, Perakakis, Nikolaos, Mohan Anjana, Ranjit, Mohan, Viswanathan, Mahapatra, Nitish R., Bornstein, Stefan R.

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing corona virus disease 2019 (COVID-19) can infect multiple tissues, including endocrine…”
Get full text

Coordinated Transcriptional Regulation of Hspa1a Gene by Multiple Transcription Factors: Crucial Roles for HSF-1, NF-Y, NF-κB, and CREB by Sasi, Binu K., Sonawane, Parshuram J., Gupta, Vinayak, Sahu, Bhavani S., Mahapatra, Nitish R.

“…Although the transcript level of inducible heat shock protein 70.3 (Hsp70.3, also known as Hspa1a) is altered in various disease states, its transcriptional…”
Get full text

Cyclic-AMP response element binding protein (CREB) and microRNA miR-29b regulate renalase gene expression under catecholamine excess conditions by Iyer, Dhanya R., Arige, Vikas, Ananthamohan, Kalyani, Sundaramurthy, Venkatasubramaniam, Tokinoya, Katsuyuki, Aoki, Kai, Kurtz, C. Lisa, Sethupathy, Praveen, Takekoshi, Kazuhiro, Mahapatra, Nitish R.

“…Renalase, a key mediator of cross-talk between kidneys and sympathetic nervous system, exerts protective roles in various cardiovascular/renal disease states…”
Get full text

Association of MMP7 -181A→G Promoter Polymorphism with Gastric Cancer Risk: INFLUENCE OF NICOTINE IN DIFFERENTIAL ALLELE-SPECIFIC TRANSCRIPTION VIA INCREASED PHOSPHORYLATION OF cAMP-RESPONSE ELEMENT-BINDING PROTEIN (CREB) by Kesh, Kousik, Subramanian, Lakshmi, Ghosh, Nillu, Gupta, Vinayak, Gupta, Arnab, Bhattacharya, Samir, Mahapatra, Nitish R, Swarnakar, Snehasikta

“…Elevated expression of matrix metalloproteinase7 (MMP7) has been demonstrated to play a pivotal role in cancer invasion. The -181A→G (rs11568818) polymorphism…”
Get full text

Catestatin is a novel endogenous peptide that regulates cardiac function and blood pressure by Mahapatra, Nitish R.

“…Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide that is formed endogenously by proteolytic cleavage of its precursor chromogranin A, a…”
Get full text

Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia‐like conditions: key roles of the transcription factors GATA2, Sp1 and TBP by Gupta, Vinayak, Khan, Abrar A., Sasi, Binu K., Mahapatra, Nitish R.

“…Monoamine oxidase A (MAOA) plays important roles in the pathogenesis of several neurological and cardiovascular disorders. The mechanism of transcriptional…”
Get full text

Catestatin reverses the hypertrophic effects of norepinephrine in H9c2 cardiac myoblasts by modulating the adrenergic signaling by Alam, Md. Jahangir, Gupta, Richa, Mahapatra, Nitish R., Goswami, Shyamal K.

“…Catestatin (CST) is a catecholamine release-inhibitory peptide secreted from the adrenergic neurons and the adrenal glands. It regulates the cardiovascular…”
Get full text

Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart by Dhat, Rohini, Mongad, Dattatray, Raji, Sivarupa, Arkat, Silpa, Mahapatra, Nitish R, Singhal, Nishant, Sitasawad, Sandhya L

“…Diabetic cardiomyopathy (DCM) is a leading cause of death in diabetic patients. Hyperglycemic myocardial microenvironment significantly alters chromatin…”
Get full text

Hypoxia-mediated regulation of mitochondrial transcription factors in renal epithelial cells: implications for hypertensive renal physiology by Natarajan, Bhargavi, Arige, Vikas, Khan, Abrar A, Reddy, S Santosh, Barthwal, Manoj K, Mahapatra, Nitish R

“…Kidneys have a high resting metabolic rate and low partial pressure of oxygen due to enhanced mitochondrial oxygen consumption and ATP production needed for…”
Get full text

An evolutionarily-conserved promoter allele governs HMG-CoA reductase expression in spontaneously hypertensive rat by Khan, Abrar A., Sundar, Poovitha, Natarajan, Bhargavi, Gupta, Vinayak, Arige, Vikas, Reddy, S. Santosh, Barthwal, Manoj K., Mahapatra, Nitish R.

“…3-Hydroxy-3-methyl glutaryl-coenzyme A reductase (Hmgcr) encodes the rate-limiting enzyme in the cholesterol biosynthesis pathway. The regulation of Hmgcr in…”
Get full text