Search Results - "Mahanthappa, N"

Blocking extracellular activation of myostatin as a strategy for treating muscle wasting by Pirruccello-Straub, M., Jackson, J., Wawersik, S., Webster, M. T., Salta, L., Long, K., McConaughy, W., Capili, A., Boston, C., Carven, G. J., Mahanthappa, N. K., Turner, K. J., Donovan, A.

“…Many growth factors are intimately bound to the extracellular matrix, with regulated processing and release leading to cellular stimulation. Myostatin and…”
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Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: roles of EGF and TGF-beta s by Mahanthappa, N K, Schwarting, G A

“…The olfactory epithelium (OE) is unique in the mammalian nervous system as a site of continual neurogenesis. Though many studies have described this process in…”
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Rat olfactory neurons can utilize the endogenous lectin, L-14, in a novel adhesion mechanism by MAHANTHAPPA, N. K, COOPER, D. N. W, BARONDES, S. H, SCHWARTING, G. A

“…L-14 is a divalent, lactosamine-binding lectin expressed in many vertebrate tissues. In the rat nervous system, L-14 expression has been observed previously in…”
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Glial Growth Factor 2, a Soluble Neuregulin, Directly Increases Schwann Cell Motility and Indirectly Promotes Neurite Outgrowth by Mahanthappa, Nagesh K, Anton, Eva S, Matthew, William D

“…Schwann cells proliferate, migrate, and act as sources of neurotrophic support during development and regeneration of peripheral nerves. Recent studies have…”
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Neural Stem Cells Are Blasting Off by Stemple, Derek L., Mahanthappa, Nagesh K.

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Sonic Hedgehog Promotes the Survival of Specific CNS Neuron Populations and Protects These Cells from Toxic Insult In Vitro by Miao, Ningning, Wang, Monica, Ott, Jennifer A, D'Alessandro, Josephine S, Woolf, Tod M, Bumcrot, David A, Mahanthappa, Nagesh K, Pang, Kevin

“…Sonic hedgehog (Shh), an axis-determining secreted protein, is expressed during early vertebrate embryogenesis in the notochord and ventral neural tube. In…”
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Schwann cell heparan sulfate proteoglycans play a critical role in glial growth factor/neuregulin signaling by Sudhalter, Judith, Whitehouse, Laura, Rusche, James R., Marchionni, Mark A., Mahanthappa, Nagesh K.

“…Glial growth factors are proteins encoded by the neuregulin gene and are thought to signal via receptor tyrosine kinases. Many neuregulin gene products bind…”
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Thy-1 involvement in neurite outgrowth: Perturbation by antibodies, phospholipase C, and mutation by Mahanthappa, Nagesh K., Patterson, Paul H.

“…Thy-1 is a major cell surface protein anchored in the plasma membrane of neurons and lymphocytes by a covalent glycophosphotidylinositide linkage. Despite…”
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Cooperative Effects of Sonic Hedgehog and NGF on Basal Forebrain Cholinergic Neurons by Reilly, Jennifer Ott, Karavanova, Irina D., Williams, Kevin P., Mahanthappa, Nagesh K., Allendoerfer, Karen L.

“…In ventromedial cells of the developing CNS, Sonic hedgehog (Shh) has been shown to affect precursor proliferation, phenotype determination, and survival. Here…”
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Translating RNA interference into therapies for human disease by Mahanthappa, Nagesh

“…RNA interference (RNAi) represents one of the most promising new frontiers in drug discovery. Breakthroughs in understanding RNA's extensive natural role in…”
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Basic FGF induces neuronal differentiation, cell division, and NGF dependence in chromaffin cells: a sequence of events in sympathetic development by Stemple, D L, Mahanthappa, N K, Anderson, D J

“…To define further the molecules that control sympathoadrenal differentiation, we have investigated the effects of FGF, NGF, and glucocorticoid on cultured…”
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Thy-1 multimerization is correlated with neurite outgrowth by Mahanthappa, Nagesh K., Patterson, Paul H.

“…Thy-1 is abundantly expressed in the vertebrate nervous system. Perturbation studies in vitro suggest that Thy-1 inhibits neurite outgrowth and stabilizes…”
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Neuregulins as potential drugs for neurological disorders by Marchionni, M A, Kirk, C J, Isaacs, I J, Hoban, C J, Mahanthappa, N K, Anton, E S, Chen, C, Wason, F, Lawson, D, Hamers, F P, Canoll, P D, Reynolds, R, Cannella, B, Meun, D, Holt, W F, Matthew, W D, Chen, L E, Gispen, W H, Raine, C S, Salzer, J L, Gwynne, D I

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Neuregulins as Potential Neuroprotective Agents by MARCHIONNI, MARK A., GRINSPAN, JUDITH B., CANOLL, PETER D., MAHANTHAPPA, NAGESH K., SALZER, JAMES L., SCHERER, STEVEN S.

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Regeneration in the auditory system: lessons from other epithelia, and persisting puzzles by Mahanthappa, N K

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Adrenal chromaffin cells as multipotential neurons for autografts by Mahanthappa, N K, Gage, F H, Patterson, P H

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Co-grafts of fetal ventral mesencephalon and fibroblasts expressing sonic hedgehog: effect on survival and function of dopamine grafts by Yurek, D M, Fletcher-Turner, A, Moore, J, Chai, L, Mahanthappa, N

“…Fibroblasts derived from the Rat2 parental cell line were genetically modified to express the cell-associated form of Sonic hedgehog (Shh) and then co-grafted…”
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Hedgehog Proteins Play A Role In Peripheral Nerve Regeneration by Engber, Tm, Allendoerfer, Kl, Berg, A, Drake, E, Mahanthappa, N, Mozell, R, Pepicelli, C, Ranciato, R, Reilly, Jo, Sah, D, Wang, S, Galdes, A.

“…Hedgehog proteins are embryonic induction factors that play a role in the development of the central and peripheral nervous systems. The Hedgehog proteins and…”
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