Search Results - "Mahangare, Sachin J"

Discovery and pre-clinical characterization of a selective PI3Kδ inhibitor, LL-00071210 in rheumatoid arthritis by Kanoje, Vijay, Pandey, Dilip, Wagh, Akshaya, Patra, Sukanya, Kumar Marisetti, Ajit, Reddy, Madhusudhan, Samant, Charudatt, Mahajan, Nilesh, Gholve, Milind, Sabde, Sudeep, Trivedi, Sneha, Bhankhede, Trupti, Patil, Vinod, Nigade, Prashant, Modi, Dipak, Mehta, Maneesh, Ahirrao, Prajakta, Tota, Swathi, Nanda, Bidyut, Pawar, Shashikant, Polawar, Anuradha, Tamane, Kaustubh, Kuldharan, Sandip, Vishwase, Gururaj, Jana, Nirmal, Mahangare, Sachin J., Vidhate, Prashant, Lagad, Dipak, Gundu, Jayasagar, Phukan, Samiron, Shukla, Manojkumar, Narasimham, Lakshmi, Nemmani, Kumar V.S., Bhonde, Mandar, Sharma, Sharad, Kamboj, Rajender K., Palle, Venkata P.

“…PI3Kδ plays a critical role in adaptive immune cell activation and function. Suppression of PI3Kδ has been shown to counter excessive triggering of immune…”
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Discovery of a Potent and Selective PI3Kδ Inhibitor ( S )-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4 H -quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models by Shukla, Manojkumar R, Patra, Sukanya, Verma, Mahip, Sadasivam, Gayathri, Jana, Nirmal, Mahangare, Sachin J, Vidhate, Prashant, Lagad, Dipak, Tarage, Anand, Cheemala, Murthy, Kulkarni, Chaitanya, Bhagwat, Shankar, Chaudhari, Vinod D, Sayyed, Majid, Pachpute, Vipul, Phadtare, Ramesh, Gole, Gopal, Phukan, Samiron, Sunkara, Brahmam, Samant, Charudatt, Shingare, Manisha, Naik, Aditya, Trivedi, Sneha, Marisetti, Ajit Kumar, Reddy, Madhusudhan, Gholve, Milind, Mahajan, Nilesh, Sabde, Sudeep, Patil, Vinod, Modi, Dipak, Mehta, Maneesh, Nigade, Prashant, Tamane, Kaustubh, Tota, Swati, Goyal, Hemant, Volam, Harish, Pawar, Shashikant, Ahirrao, Prajakta, Dinchhana, Lal, Mallurwar, Sadanand, Akarte, Atul, Bokare, Anand, Kanhere, Rupesh, Reddy, Neetinkumar, Koul, Sarita, Dandekar, Manoj, Singh, Minakshi, Bernstein, Peter R, Narasimham, Lakshmi, Bhonde, Mandar, Gundu, Jayasagar, Goel, Rajan, Kulkarni, Sanjeev, Sharma, Sharad, Kamboj, Rajender Kumar, Palle, Venkata P

“…PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors…”
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Discovery of a Potent and Selective PI3Kδ Inhibitor (S)‑2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl‑4H‑quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models by Shukla, Manojkumar R, Patra, Sukanya, Verma, Mahip, Sadasivam, Gayathri, Jana, Nirmal, Mahangare, Sachin J, Vidhate, Prashant, Lagad, Dipak, Tarage, Anand, Cheemala, Murthy, Kulkarni, Chaitanya, Bhagwat, Shankar, Chaudhari, Vinod D, Sayyed, Majid, Pachpute, Vipul, Phadtare, Ramesh, Gole, Gopal, Phukan, Samiron, Sunkara, Brahmam, Samant, Charudatt, Shingare, Manisha, Naik, Aditya, Trivedi, Sneha, Marisetti, Ajit Kumar, Reddy, Madhusudhan, Gholve, Milind, Mahajan, Nilesh, Sabde, Sudeep, Patil, Vinod, Modi, Dipak, Mehta, Maneesh, Nigade, Prashant, Tamane, Kaustubh, Tota, Swati, Goyal, Hemant, Volam, Harish, Pawar, Shashikant, Ahirrao, Prajakta, Dinchhana, Lal, Mallurwar, Sadanand, Akarte, Atul, Bokare, Anand, Kanhere, Rupesh, Reddy, Neetinkumar, Koul, Sarita, Dandekar, Manoj, Singh, Minakshi, Bernstein, Peter R, Narasimham, Lakshmi, Bhonde, Mandar, Gundu, Jayasagar, Goel, Rajan, Kulkarni, Sanjeev, Sharma, Sharad, Kamboj, Rajender Kumar, Palle, Venkata P

“…PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors…”
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