Search Results - "Mahale, S.D."

Identification of the region 285–309 of follicle stimulating hormone receptor as a bioneutralizing epitope by Ghosalkar, J.D, Dharma, S.J, Nandedkar, T.D, Mahale, S.D

“…Abstract Structure–function relationship studies of the follicle stimulating hormone and its receptor assume importance as this hormone is essential for…”
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Disulfide bonds Cys9–Cys57, Cys34–Cys88 and Cys38–Cys90 of the β-subunit of human chorionic gonadotropin are crucial for heterodimer formation with the α-subunit: experimental evidence for the conclusions from the crystal structure of hCG by Mishra, A.K, Mahale, S.D, Iyer, K.S

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Disulfide bonds Cys 9–Cys 57, Cys 34–Cys 88 and Cys 38–Cys 90 of the β-subunit of human chorionic gonadotropin are crucial for heterodimer formation with the α-subunit: experimental evidence for the conclusions from the crystal structure of hCG by Mishra, A.K, Mahale, S.D, Iyer, K.S

“…Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone essential for the establishment and maintenance of pregnancy. The α- and β-subunits…”
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Attempt to map the receptor binding sites of human follicle‐stimulating hormone using disulfide peptides of its β ‐subunit indicates major involvement of the regions around disulfide bonds Cys 28 –Cys 82 and Cys 32 –Cys 84 in receptor binding of the hormone by Jetly, N.M., Iyer, K.S., Mahale, S.D., Hosur, M.V.

“…Follicle‐stimulating hormone (FSH) is a heterodimeric glycoprotein hormone secreted by the anterior pituitary. It plays a very important role in…”
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Mapping the receptor binding regions of human chorionic gonadotropin (hCG) using disulfide peptides of its β‐subunit: possible involvement of the disulfide bonds Cys 9 −Cys 57 and Cys 23 −Cys 72 in receptor binding of the hormone by Mishra, A.K., Mahale, S.D., Iyer, K.S.

“…Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone essential for the establishment and maintenance of pregnancy. The α‐ and β‐subunits…”
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Mapping the receptor binding regions of human chorionic gonadotropin (hCG) using disulfide peptides of its β-subunit: possible involvement of the disulfide bonds Cys9−Cys57 and Cys23−Cys72 in receptor binding of the hormone by Mishra, A.K., Mahale, S.D., Iyer, K.S.

“…: Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone essential for the establishment and maintenance of pregnancy. The α‐ and…”
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Secondary structure analysis of synthetic peptides of the extracellular domain of the human follicle-stimulating hormone receptor by Kene, P.S., Behere, D.V., Mahale, S.D.

“…:  Follicle‐stimulating hormone receptor (FSHR) is a glycoprotein hormone receptor and possesses a large extracellular domain (ECD) instrumental in hormone…”
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Attempt to map the receptor binding sites of human follicle-stimulating hormone using disulfide peptides of its β-subunit indicates major involvement of the regions around disulfide bonds Cys28-Cys82 and Cys32-Cys84 in receptor binding of the hormone by Jetly, N.M., Iyer, K.S., Mahale, S.D., Hosur, M.V.

“…:  Follicle‐stimulating hormone (FSH) is a heterodimeric glycoprotein hormone secreted by the anterior pituitary. It plays a very important role in…”
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Comparison of antibodies raised against the peptide 10–24 of chicken riboflavin carrier protein (cRCP) by classical and multiple antigen peptide (MAP) approaches by Mahale, S.D., Pereira, J., Natraj, U., Iyer, K.S.N.

“…Riboflavin carrier protein is an essential protein required for the growth and development of the embryo and hence for the maintenance of pregnancy. Our…”
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Termination of pregnancy in mice following administration of antibodies to the pentadecapeptide 10-24 of chicken riboflavin carrier protein: identification of a bioneutralizing epitope of chicken riboflavin carrier protein by Natraj, U, Sabnis, T N, Mahale, S D, Iyer, K S

“…Our studies have shown that the administration of antibodies to chicken riboflavin carrier protein (cRCP) or disulfide-reduced carboxymethylated cRCP (RCM-RCP)…”
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Enhancement of in vitro release of FSH from rat pituitaries by a synthetic nonapeptide fragment of human seminal plasma inhibin by Hurkadli, K S, Mahale, S D, Iyer, K S, Sheth, A R

“…A synthetic C-terminal nonapeptide fragment of human seminal plasma inhibin preferentially enhances the basal release of FSH from rat pituitaries incubated in…”
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Studies on the carboxyl terminal peptides of human seminal plasma inhibin (HSPI). Chemical synthesis and in vivo biological activity of the disulfide loop peptide 67-94 of HSPI by Mahale, S D, Sheth, A R, Iyer, K S

“…Observation of contradictory results with the in vitro assays for inhibin-like activity of the carboxyl terminal 28 amino acid peptide 67-94 with a disulfide…”
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Studies on the delineation of the antigenic determinants of chicken riboflavin carrier protein (cRCP). Identification of a determinant in the region 10-24 of the protein by Mahale, S D, Kadam, L R, Pereira, J, Natraj, U, Iyer, K S

“…As riboflavin carrier proteins play a critical role in the maintenance of pregnancy, studies on the immunology of these proteins have become very relevant…”
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Search for peptide immunogens of the beta-subunit of human chorionic gonadotropin (hCG) capable of eliciting hormone specific and neutralizing antisera. Identification of an undecapeptide eliciting hCG-specific antisera by Iyer, K S, Upadhye, S, Kadam, L R, Mahale, S D, Dhanasekharan, S, Natraj, U, Nandedkar, T D

“…The work reported herein describes our attempts to identify peptide immunogens of the beta-subunit of the pregnancy-specific placental hormone, human chorionic…”
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