Search Results - "Mahale, S D"

Increased rate of miscarriage during second wave of COVID‐19 pandemic in India by Gajbhiye, R. K., Tilve, A., Kesarwani, S., Srivastava, S., Kore, S. J., Patil, K., Mahale, S. D., Mahajan, N. N.

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Identification of the structural and functional determinants of the extracellular domain of the human follicle stimulating hormone receptor by Kene, PS, Nalavadi, VC, Dighe, RR, Iyer, KS, Mahale, SD

“…The extracellular domain (ECD) of the human follicle-stimulating hormone receptor (hFSHR) is believed to be the major determinant of hormone selectivity…”
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Identification of the region 285–309 of follicle stimulating hormone receptor as a bioneutralizing epitope by Ghosalkar, J.D, Dharma, S.J, Nandedkar, T.D, Mahale, S.D

“…Abstract Structure–function relationship studies of the follicle stimulating hormone and its receptor assume importance as this hormone is essential for…”
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Disulfide bonds Cys(9)-Cys(57), Cys(34)-Cys(88) and Cys(38)-Cys(90) of the beta-subunit of human chorionic gonadotropin are crucial for heterodimer formation with the alpha-subunit: experimental evidence for the conclusions from the crystal structure of hCG by Mishra, A K, Mahale, S D, Iyer, K S

“…Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone essential for the establishment and maintenance of pregnancy. The alpha- and…”
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Polymeric nanoparticle formulation of octapeptide (NP-OP): in vitro release and in vivo effect in common marmosets, Callithrix jacchus Linn by Nandedkar, T D, Sagvekar, P, Thakur, B, Navlakhe, R, Chitnis, S, Mahale, S D, D'Souza, S, Patel, K D, Vavia, P R

“…Octapeptide (OP)/FSH-Receptor Binding Inhibitor-8 (FRBI-8), is a synthetic peptide corresponding to N-terminal sequence of purified fraction of Follicle…”
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A detailed study of the L2β long-loop region of human chorionic gonadotrophin suggests it to be spatially close to, but not part of, the receptor-binding site by JAGTAP, D. D, MAHALE, S. D, MISHRA, A. K, NANDEDKAR, T. D, LYER, K. S

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Comparison of antibodies raised against the peptide 10–24 of chicken riboflavin carrier protein (cRCP) by classical and multiple antigen peptide (MAP) approaches by Mahale, S.D., Pereira, J., Natraj, U., Iyer, K.S.N.

“…Riboflavin carrier protein is an essential protein required for the growth and development of the embryo and hence for the maintenance of pregnancy. Our…”
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Secondary structure analysis of synthetic peptides of the extracellular domain of the human follicle-stimulating hormone receptor by Kene, P.S., Behere, D.V., Mahale, S.D.

“…:  Follicle‐stimulating hormone receptor (FSHR) is a glycoprotein hormone receptor and possesses a large extracellular domain (ECD) instrumental in hormone…”
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A detailed study of the L2beta long-loop region of human chorionic gonadotrophin suggests it to be spatially close to, but not part of, the receptor-binding site by Jagtap, DD, Mahale, SD, Mishra, AK, Nandedkar, TD, Iyer, KS

“…An in-depth study of the L2beta long-loop region of human chorionic gonadotrophin (hCG), earlier identified to be a conformational bioneutralization epitope…”
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Mapping the receptor binding regions of human chorionic gonadotropin (hCG) using disulfide peptides of its beta-subunit: possible involvement of the disulfide bonds Cys(9)-Cys(57) and Cys(23)-Cys(72) in receptor binding of the hormone by Mishra, A K, Mahale, S D, Iyer, K S

“…Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone essential for the establishment and maintenance of pregnancy. The alpha- and…”
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Termination of pregnancy in mice following administration of antibodies to the pentadecapeptide 10-24 of chicken riboflavin carrier protein: identification of a bioneutralizing epitope of chicken riboflavin carrier protein by Natraj, U, Sabnis, T N, Mahale, S D, Iyer, K S

“…Our studies have shown that the administration of antibodies to chicken riboflavin carrier protein (cRCP) or disulfide-reduced carboxymethylated cRCP (RCM-RCP)…”
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Effect of ovarian follicular fluid peptide (OFFP) on FSH and EGF binding to granulosa cells by Shahid, J K, Nandedkar, T D, Iyer, K S, Mahale, S D

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Studies on the carboxyl terminal peptides of human seminal plasma inhibin (HSPI). Chemical synthesis and in vivo biological activity of the disulfide loop peptide 67-94 of HSPI by Mahale, S D, Sheth, A R, Iyer, K S

“…Observation of contradictory results with the in vitro assays for inhibin-like activity of the carboxyl terminal 28 amino acid peptide 67-94 with a disulfide…”
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Studies on the delineation of the antigenic determinants of chicken riboflavin carrier protein (cRCP). Identification of a determinant in the region 10-24 of the protein by Mahale, S D, Kadam, L R, Pereira, J, Natraj, U, Iyer, K S

“…As riboflavin carrier proteins play a critical role in the maintenance of pregnancy, studies on the immunology of these proteins have become very relevant…”
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Enhancement of in vitro release of FSH from rat pituitaries by a synthetic nonapeptide fragment of human seminal plasma inhibin by Hurkadli, K S, Mahale, S D, Iyer, K S, Sheth, A R

“…A synthetic C-terminal nonapeptide fragment of human seminal plasma inhibin preferentially enhances the basal release of FSH from rat pituitaries incubated in…”
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Autologous Biological Response Modification of the Gonadotropin Receptor by Mahale, Smita D., Cavanagh, John, Schmidt, Anja, MacColl, Robert, Dias, James A.

“…It is generally held with respect to heterotrimeric guanine nucleotide binding protein-coupled receptors that binding of ligand stabilizes a conformation of…”
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A synthetic decapeptide analogue of human seminal plasma inhibin exhibiting specific suppression of follicle stimulating hormone release in rats by Iyer, K S, Mahale, S D, Hurkadli, K S, Sheth, A R

“…Synthesis and biological profile of a decapeptide analogue, [Tyr85, Cys(Acm)87]85-94 of human seminal plasma inhibin (HSPI) are described. The peptide…”
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Preferential elevation of the levels of follitropin by a synthetic carboxy terminal nonapeptide 86-94 of human seminal plasma inhibin by Niyer, K S, Mahale, S D, Hurkadli, K S, Sheth, A R

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Search for peptide immunogens of the beta-subunit of human chorionic gonadotropin (hCG) capable of eliciting hormone specific and neutralizing antisera. Identification of an undecapeptide eliciting hCG-specific antisera by Iyer, K S, Upadhye, S, Kadam, L R, Mahale, S D, Dhanasekharan, S, Natraj, U, Nandedkar, T D

“…The work reported herein describes our attempts to identify peptide immunogens of the beta-subunit of the pregnancy-specific placental hormone, human chorionic…”
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Effect of Active Immunization with the C-terminal 67-94 (R-28) Region of Human Seminal Plasma Inhibin on the Fecundity of Adult Male Rabbits by Mehta, Monica N., Mahale, Smita D., Iyer, K.S., Vanage, Geeta R., Raghavan, Vijaya P., Moodbidri, Sudhir B.

“…PROBLEM: To characterize the specificity of antibodies to the synthetic C‐terminal 67–94 (R‐28) peptide of human seminal plasma inhibin (hSPI), and to examine…”
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