Search Results - "Mahadevappa, Ravikiran"

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  1. 1

    DNA replication licensing proteins: Saints and sinners in cancer by Mughal, Muhammad Jameel, Mahadevappa, Ravikiran, Kwok, Hang Fai

    Published in Seminars in cancer biology (01-10-2019)
    “…Pictorial abstract: DNA replication is initiated and regulated by DNA replication licensing complex which includes ORC, CDC6, Cdt1 and MCM2–7 complex. A…”
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    Journal Article
  2. 2

    The prognostic significance of Cdc6 and Cdt1 in breast cancer by Mahadevappa, Ravikiran, Neves, Henrique, Yuen, Shun Ming, Bai, Yuchen, McCrudden, Cian M., Yuen, Hiu Fung, Wen, Qing, Zhang, Shu Dong, Kwok, Hang Fai

    Published in Scientific reports (20-04-2017)
    “…DNA replication is a critical step in cell proliferation. Overexpression of MCM2-7 genes correlated with poor prognosis in breast cancer patients. However, the…”
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    Journal Article
  3. 3

    Megalin in acute kidney injury: foe and friend by Mahadevappa, Ravikiran, Nielsen, Rikke, Christensen, Erik Ilsø, Birn, Henrik

    “…The kidney proximal tubule is a key target in many forms of acute kidney injury (AKI). The multiligand receptor megalin is responsible for the normal proximal…”
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    Journal Article
  4. 4

    Phytochemicals - A Novel and Prominent Source of Anti-cancer Drugs Against Colorectal Cancer by Mahadevappa, Ravikiran, Kwok, Hang Fai

    “…Colorectal cancer (CRC) is a malignant disease whose incidence and mortality rates are greatly influenced by environmental factors. Under-treatment of CRC such…”
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    Journal Article
  5. 5

    DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer by Mahadevappa, Ravikiran, Neves, Henrique, Yuen, Shun Ming, Jameel, Muhammad, Bai, Yuchen, Yuen, Hiu-Fung, Zhang, Shu-Dong, Zhu, Youzhi, Lin, Yao, Kwok, Hang Fai

    Published in Cancers (22-08-2018)
    “…Breast cancer is one of the most common malignancies in women worldwide. In breast cancer, the cell proliferation rate is known to influence the cancer…”
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    Journal Article
  6. 6

    Venom-based peptide therapy: insights into anti-cancer mechanism by Ma, Rui, Mahadevappa, Ravikiran, Kwok, Hang Fai

    Published in Oncotarget (21-11-2017)
    “…The 5-year relative survival rate of all types of cancer has increased significantly over the past three decades partly due to the targeted therapy. However,…”
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    Journal Article
  7. 7

    Cancer plasticity: Investigating the causes for this agility by Saha, Shubhraneel, Pradhan, Nikita, B, Neha, Mahadevappa, Ravikiran, Minocha, Shilpi, Kumar, Saran

    Published in Seminars in cancer biology (01-01-2023)
    “…Cancer is not a hard-wired phenomenon but an evolutionary disease. From the onset of carcinogenesis, cancer cells continuously adapt and evolve to satiate…”
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    Journal Article
  8. 8

    Triggering of cancer cell cycle arrest by a novel scorpion venom‐derived peptide—Gonearrestide by Li, Bin, Lyu, Peng, Xi, Xinping, Ge, Lilin, Mahadevappa, Ravikiran, Shaw, Chris, Kwok, Hang Fai

    Published in Journal of cellular and molecular medicine (01-09-2018)
    “…In this study, a novel scorpion venom‐derived peptide named Gonearrestide was identified in an in‐house constructed scorpion venom library through a…”
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    Journal Article
  9. 9

    Venom Peptides: Improving Specificity in Cancer Therapy by Mahadevappa, Ravikiran, Ma, Rui, Kwok, Hang Fai

    Published in Trends in cancer (01-09-2017)
    “…Venom peptides (VPs) exhibit high specificity and selectivity towards cancer cells, with effects on cell proliferation, invasion, migration, and angiogenesis,…”
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  10. 10

    Over-Activation of Minichromosome Maintenance Protein 10 Promotes Genomic Instability in Early Stages of Breast Cancer by Mughal, Muhammad Jameel, Chan, Kin Iong, Mahadevappa, Ravikiran, Wong, Sin Wa, Wai, Kit Cheng, Kwok, Hang Fai

    “…Genomic instability is considered as one of the key hallmark during cancer development and progression. Cellular mechanisms, such as DNA replication…”
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    Journal Article