Search Results - "Mah, Sarah M."

Sense of belonging to community and avoidable hospitalization: a population-based cohort study of 456,415 Canadians by Lu, Mindy, Mah, Sarah M., Rosella, Laura C.

“…A sense of belonging to a community is a dimension of subjective well-being that is of growing population health interest. We evaluated sex-stratified…”
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The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes by Teh, Ai Ling, Pan, Hong, Chen, Li, Ong, Mei-Lyn, Dogra, Shaillay, Wong, Johnny, MacIsaac, Julia L, Mah, Sarah M, McEwen, Lisa M, Saw, Seang-Mei, Godfrey, Keith M, Chong, Yap-Seng, Kwek, Kenneth, Kwoh, Chee-Keong, Soh, Shu-E, Chong, Mary F F, Barton, Sheila, Karnani, Neerja, Cheong, Clara Y, Buschdorf, Jan Paul, Stünkel, Walter, Kobor, Michael S, Meaney, Michael J, Gluckman, Peter D, Holbrook, Joanna D

“…Integrating the genotype with epigenetic marks holds the promise of better understanding the biology that underlies the complex interactions of inherited and…”
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DNA methylation signature of human fetal alcohol spectrum disorder by Portales-Casamar, Elodie, Lussier, Alexandre A, Jones, Meaghan J, MacIsaac, Julia L, Edgar, Rachel D, Mah, Sarah M, Barhdadi, Amina, Provost, Sylvie, Lemieux-Perreault, Louis-Philippe, Cynader, Max S, Chudley, Albert E, Dubé, Marie-Pierre, Reynolds, James N, Pavlidis, Paul, Kobor, Michael S

“…Prenatal alcohol exposure is the leading preventable cause of behavioral and cognitive deficits, which may affect between 2 and 5 % of children in North…”
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Active living environments, physical activity and premature cardiometabolic mortality in Canada: a nationwide cohort study by Mah, Sarah M, Sanmartin, Claudia, Riva, Mylène, Dasgupta, Kaberi, Ross, Nancy A

“…ObjectiveTo evaluate sex-specific and age-specific associations of active living environments (ALEs) with premature cardiometabolic…”
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An international comparative study of active living environments and hospitalization for Wales and Canada by Mah, Sarah M., Dasgupta, Kaberi, Akbari, Ashley, Ross, Nancy A., Fry, Richard

“…Rationale: Previous studies indicate active living environments (ALEs) are associated with higher physical activity levels across different geographic…”
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Social Cohesion and Community Resilience During COVID-19 and Pandemics: A Rapid Scoping Review to Inform the United Nations Research Roadmap for COVID-19 Recovery by Jewett, Rae L., Mah, Sarah M., Howell, Nicholas, Larsen, Mandi M.

“…Shock events uncover deficits in social cohesion and exacerbate existing social inequalities at the household, community, local, regional, and national levels…”
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Worldwide patterns of human epigenetic variation by Carja, Oana, MacIsaac, Julia L., Mah, Sarah M., Henn, Brenna M., Kobor, Michael S., Feldman, Marcus W., Fraser, Hunter B.

“…DNA methylation is an epigenetic modification, influenced by both genetic and environmental variation, that plays a key role in transcriptional regulation and…”
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A national cohort study of community belonging and its influence on premature mortality by Michalski, Camilla, Hurst, Mack, Diemert, Lori, Mah, Sarah M, Helliwell, John, Kim, Eric S, Rosella, Laura C

“…Community belonging, an important constituent of subjective well-being, is an important target for improving population health. Ageing involves transitioning…”
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Epigenetic correlates of neonatal contact in humans by Moore, Sarah R, McEwen, Lisa M, Quirt, Jill, Morin, Alex, Mah, Sarah M, Barr, Ronald G, Boyce, W Thomas, Kobor, Michael S

“…Animal models of early postnatal mother-infant interactions have highlighted the importance of tactile contact for biobehavioral outcomes via the modification…”
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Infinium monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) by Ong, Mei-Lyn, Tan, Peck Yean, MacIsaac, Julia L, Mah, Sarah M, Buschdorf, Jan Paul, Cheong, Clara Y, Stunkel, Walter, Chan, Louiza, Gluckman, Peter D, Chng, Keefe, Kobor, Michael S, Meaney, Michael J, Holbrook, Joanna D

“…The Infinium Human Methylation450 BeadChip Array (Infinium 450K) is a robust and cost-efficient survey of genome-wide DNA methylation patterns. Macaca…”
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Trends in DNA Methylation with Age Replicate Across Diverse Human Populations by Gopalan, Shyamalika, Carja, Oana, Fagny, Maud, Patin, Etienne, Myrick, Justin W, McEwen, Lisa M, Mah, Sarah M, Kobor, Michael S, Froment, Alain, Feldman, Marcus W, Quintana-Murci, Lluis, Henn, Brenna M

“…Aging is associated with widespread changes in genome-wide patterns of DNA methylation. Thousands of CpG sites whose tissue-specific methylation levels are…”
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Exploring the use of experimental small area estimates to examine the relationship between individual-level and area-level community belonging and self-rated health by Mah, Sarah M, Brown, Mark, Colley, Rachel C, Rosella, Laura C, Schellenberg, Grant, Sanmartin, Claudia

“…Small area estimation refers to statistical modelling procedures that leverage information or "borrow strength" from other sources or variables. This is done…”
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Does living near hospital obscure the association between active living environments and hospitalization? by Mah, Sarah M., Herrmann, Thomas, Sanmartin, Claudia, Riva, Mylène, Dasgupta, Kaberi, Ross, Nancy A.

“…Hospitals tend to be among the destinations that make densely populated, well-connected neighbourhoods more conducive to active living. In this study, we…”
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DNA methylation profiling in human Huntington's disease brain by De Souza, Rebecca A G, Islam, Sumaiya A, McEwen, Lisa M, Mathelier, Anthony, Hill, Austin, Mah, Sarah M, Wasserman, Wyeth W, Kobor, Michael S, Leavitt, Blair R

“…Despite extensive progress in Huntington's disease (HD) research, very little is known about the association of epigenetic variation and HD pathogenesis in…”
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Overcrowded housing during adolescence and future risk of premature mortality: a 28-year follow-up of 556,191 adolescents from Switzerland by Mah, Sarah M., Rosella, Laura C., Kivimäki, Mika, Carmeli, Cristian

“…Few large-scale studies have examined the health impacts of overcrowded housing in European countries. The aim of this study was to assess whether household…”
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A pooling-based approach to mapping genetic variants associated with DNA methylation by Kaplow, Irene M, MacIsaac, Julia L, Mah, Sarah M, McEwen, Lisa M, Kobor, Michael S, Fraser, Hunter B

“…DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic…”
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Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes by Chen, Li, Pan, Hong, Tuan, Ta Anh, Teh, Ai Ling, MacIsaac, Julia L, Mah, Sarah M, McEwen, Lisa M, Li, Yue, Chen, Helen, Broekman, Birit F P, Buschdorf, Jan Paul, Chong, Yap Seng, Kwek, Kenneth, Saw, Seang Mei, Gluckman, Peter D, Fortier, Marielle V, Rifkin-Graboi, Anne, Kobor, Michael S, Qiu, Anqi, Meaney, Michael J, Holbrook, Joanna D

“…Early life environments interact with genotype to determine stable phenotypic outcomes. Here we examined the influence of a variant in the brain-derived…”
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Comprehensive analysis of mammalian miRNA species and their role in myeloid cells by Kuchenbauer, Florian, Mah, Sarah M., Heuser, Michael, McPherson, Andrew, Rüschmann, Jens, Rouhi, Arefeh, Berg, Tobias, Bullinger, Lars, Argiropoulos, Bob, Morin, Ryan D., Lai, David, Starczynowski, Daniel T., Karsan, Aly, Eaves, Connie J., Watahiki, Akira, Wang, Yuzhuo, Aparicio, Samuel A., Ganser, Arnold, Krauter, Jürgen, Döhner, Hartmut, Döhner, Konstanze, Marra, Marco A., Camargo, Fernando D., Palmqvist, Lars, Buske, Christian, Humphries, R. Keith

“…Processing of pre-miRNA through Dicer1 generates an miRNA duplex that consists of an miRNA and miRNA* strand. Despite the general view that miRNA*s have no…”
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MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia by Gentner, Bernhard, Pochert, Nicole, Rouhi, Arefeh, Boccalatte, Francesco, Plati, Tiziana, Berg, Tobias, Sun, Su Ming, Mah, Sarah M, Mirkovic-Hösle, Milijana, Ruschmann, Jens, Muranyi, Andrew, Leierseder, Simon, Argiropoulos, Bob, Starczynowski, Daniel T, Karsan, Aly, Heuser, Michael, Hogge, Donna, Camargo, Fernando D, Engelhardt, Stefan, Döhner, Hartmut, Buske, Christian, Jongen-Lavrencic, Mojca, Naldini, Luigi, Humphries, R. Keith, Kuchenbauer, Florian

“…A precise understanding of the role of miR-223 in human hematopoiesis and in the pathogenesis of acute myeloid leukemia (AML) is still lacking. By measuring…”
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Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates by Gurnot, Cécile, Martin-Subero, Ignacio, Mah, Sarah M, Weikum, Whitney, Goodman, Sarah J, Brain, Ursula, Werker, Janet F, Kobor, Michael S, Esteller, Manel, Oberlander, Tim F, Hensch, Takao K

“…Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances…”
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