Search Results - "Mah, H D"

Absolute stereochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by Yagi, H, Akagi, H, Thakker, D. R, Mah, H. D, Koreeda, M, Jerina, D. M

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Evidence for bay region activation of chrysene 1,2-dihydrodiol to an ultimate carcinogen by Levin, W, Wood, A W, Chang, R L, Yagi, H, Mah, H D, Jerina, D M, Conney, A H

“…The tumor-initiating activities of chrysene and the three metabolically possible trans-dihydrodiols at the 1,2-, 3,4-, and 5,6-positions of chyrsene were…”
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Differences in Mutagenicity and Cytotoxicity of (+)- and (-)-benzo[a]pyrene 4,5-Oxide: A Synergistic Interaction of Enantiomers by Chang, R. L., Wood, A. W., Levin, W., Mah, H. D., Thakker, D. R., Jerina, D. M., Conney, A. H.

“…In order to study the biological effects of (+)- and (-)-benzo[a]pyrene 4,5-oxide, a synthesis of these molecules has been developed based on the resolution of…”
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Structural requirements for the metabolic activation of benzo[a]pyrene to mutagenic products: effects of modifications in the 4,5-, 7,8-, and 9,10-positions by Wood, A W, Levin, W, Lu, A Y, Ryan, D, West, S B, Yagi, H, Mah, H D, Jerina, D M, Conney, A H

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High carcinogenicity of 2-hydroxybenzo(a)pyrene on mouse skin by Wislocki, P G, Chang, R L, Wood, A W, Levin, W, Yagi, H, Hernandez, O, Mah, H D, Dansette, P M, Jerina, D M, Conney, A H

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A synthetic approach to some tetrapyrranes by MacDonald, S F, Mah, H D, Chen, M F

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Adenosine-dependent formation of cyclic AMP in brain slices by Mah, H D, Daly, J W

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Carcinogenicity of benzo[a]pyrene and thirteen of its derivatives in C3H/fCum mice by Kouri, R E, Wood, A W, Levin, W, Rude, T H, Yagi, H, Mah, H D, Jerina, D M, Conney, A H

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Fluorine substitution as a probe for the role of the 6-position of benzo[a]pyrene in carcinogenesis by Buening, M K, Levin, W, Wood, A W, Chang, R L, Agranat, I, Rabinovitz, M, Buhler, D R, Mah, H D, Hernandez, O, Simpson, R B, Jerina, D M, Conney, A H, Miller, E C, Miller, J A

“…The tumorigenic activities of benzo[a]pyrene (BP) and 6-fluorobenzo[a]pyrene (6-F-BP) were compared to determine whether an unsubstituted 6-position is…”
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Mutagenicity and tumorigenicity of phenanthrene and chrysene epoxides and diol epoxides by Wood, A W, Chang, R L, Levin, W, Ryan, D E, Thomas, P E, Mah, H D, Karle, J M, Yagi, H, Jerina, D M, Conney, A H

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Stereoselectivity of rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide by Armstrong, R N, Levin, W, Ryan, D E, Thomas, P E, Mah, H D, Jerina, D M

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Intracellular formation of analogs of cyclic AMP. Studies with brain slices labeled with radioactive derivatives of adenine and adenosine by Mah, H D, Daly, J W

“…A variety of radioactive analogs of adenine and adenosine were incubated with guinea pig cerebral cortical slices. Neither 1,N6-etheno[14C] adenosine nor…”
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Carcinogenicity of 2-hydroxybenzo(a)pyrene and 6-hydroxybenzo(a)pyrene in newborn mice by Chang, R L, Wislocki, P G, Kapitulnik, J, Wood, A W, Levin, W, Yagi, H, Mah, H D, Jerina, D M, Conney, A H

“…Benzo(a)pyrene (BP), 2-hydroxybenzo(a)pyrene (2-HOBP), and 6-hydroxybenzo(a)pyrene (6-HOBP) were tested for tumorigenicity by i.p. injection into newborn mice…”
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Absolute sterochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzol[a]pyrene by Yagi, H, Akagi, H, Thakker, D R, Mah, H D, Koreeda, M, Jerina, D M

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High mutageniticity of metabolically activated chrysene 1,2 dihydrodiol: evidence for bay region activation of chrysene by Wood, A W, Levin, W, Ryan, D, Thomas, P E, Yagi, H, Mah, H D, Thakker, D R, Jerina, D M, Conney, A H

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Rearrangement of 1,3-thiazolidine sulfoxides by Mah, He Duck, Lee, Wha Suk

“…Oxidation of 1,3‐thiazolidines 3 gave a mixture of cis‐ and trans‐sulfoxides 4 and 5, major and minor, respectively. In the presence of an acid catalyst both…”
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Conversion of 1,3-thiazolidine and its sulfoxide to dihydro-1,4-thiazine by Lee, Wha Suk, Nam, Kee Dal, Hahn, Hoh-Gyu, Mah, He Duck

“…Two methods for constructing dihydro‐1,4‐thiazine 4 were described. 1,3‐Thiazolidines 5 were converted to dihydro‐1,4‐thiazines 4 by chlorinolysis through the…”
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Synthesis of the non-K-region and K-region trans-dihydrodiols of benzo[e]pyrene by Lehr, Roland E, Taylor, Charles W, Kumar, Subah, Mah, He Duck, Jerina, Donald M

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