Search Results - "Magwere, Tapiwanashe"

Heterogeneous role of the glutathione antioxidant system in modulating the response of ESFT to fenretinide in normoxia and hypoxia by Magwere, Tapiwanashe, Burchill, Susan A

“…Glutathione (GSH) is implicated in drug resistance mechanisms of several cancers and is a key regulator of cell death pathways within cells. We studied Ewing's…”
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The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster by Magwere, Tapiwanashe, West, Melanie, Riyahi, Kumars, Murphy, Michael P., Smith, Robin A.J., Partridge, Linda

“…We used the fruit fly Drosophila melanogaster to test the effects of feeding the superoxide dismutase (SOD) mimetic drugs Euk-8 and -134 and the…”
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Escaping immune surveillance in cancer: is denbinobin the panacea? by Magwere, Tapiwanashe

“…The bane of anti‐cancer therapy is usually the development of resistance to apoptosis in malignant cells. Identification of strategies to re‐sensitize cancer…”
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Sex Differences in the Effect of Dietary Restriction on Life Span and Mortality Rates in Female and Male Drosophila Melanogaster by Magwere, Tapiwanashe, Chapman, Tracey, Partridge, Linda

“…Dietary restriction (DR) has been shown to increase life span in taxonomically diverse animal species. In this study we tested for sex differences in the…”
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Biomarkers of aging in Drosophila by Jacobson, Jake, Lambert, Adrian J., Portero‐Otín, Manuel, Pamplona, Reinald, Magwere, Tapiwanashe, Miwa, Satomi, Driege, Yasmine, Brand, Martin D., Partridge, Linda

“…Summary Low environmental temperature and dietary restriction (DR) extend lifespan in diverse organisms. In the fruit fly Drosophila, switching flies between…”
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Oxidative stress and therapeutic opportunities: focus on the Ewing's sarcoma family of tumors by Smith, Danielle G, Magwere, Tapiwanashe, Burchill, Susan A

“…Reactive oxygen species (ROS) are highly reactive by-products of energy production that can have detrimental as well as beneficial effects. Unchecked, high…”
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Manipulation of oxidative stress to induce cell death in Ewing’s sarcoma family of tumours by Magwere, Tapiwanashe, Myatt, Stephen S, Burchill, Susan A

“…Abstract Ewing’s sarcoma family of tumours (ESFT) are childhood cancers whose aggressive behaviour and propensity to relapse prompts the need for new treatment…”
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Flight Activity, Mortality Rates, and Lipoxidative Damage in Drosophila by Magwere, Tapiwanashe, Pamplona, Reinald, Miwa, Satomi, Martinez-Diaz, Pedro, Portero-Otin, Manuel, Brand, Martin D., Partridge, Linda

“…In this study, the effect of flight activity on mortality rates and lipoxidative damage in Drosophila was determined to identify mechanisms through which…”
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Oxidative stress and therapeutic opportunities: focus on the Ewing'a[euro][TM]s sarcoma family of tumors by Smith, Danielle G, Magwere, Tapiwanashe, Burchill, Susan A

“…Reactive oxygen species (ROS) are highly reactive by-products of energy production that can have detrimental as well as beneficial effects. Unchecked, high…”
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Mini review - Chloroquine has not disappeared by Cooper, Ross G, Magwere, Tapiwanashe

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The Effect of Dietary Restriction on Mitochondrial Protein Density and Flight Muscle Mitochondrial Morphology in Drosophila by Magwere, Tapiwanashe, Goodall, Steve, Skepper, Jeremy, Mair, William, Brand, Martin D., Partridge, Linda

“…Dietary restriction (DR) extends life span in diverse organisms and may do so by attenuating production of mitochondrial reactive oxygen species (ROS)…”
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Chloroquine has not Disappeared by Cooper, Ross G, Magwere, Tapiwanashe

“…Chloroquine (CHQ), an antimalarial, is also used as an anti-inflammatory drug for systemic lupus erythematosus and rheumatoid arthritis (RA)…”
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Effects of Chloroquine Treatment on Antioxidant Enzymes in Rat Liver and Kidney by Magwere, Tapiwanashe, Naik, Yogeshkumar S, Hasler, Julia A

“…The effect of chloroquine (CHQ) administration on antioxidant enzymes in rat liver and kidney was studied. Male Sprague–Dawley rats were administered 20 mg/kg…”
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Primaquine alters antioxidant enzyme profiles in rat liver and kidney by Magwere, T, Naik, Y S, Hasler, J A

“…The effects of primaquine treatment on antioxidant enzyme activities were investigated in rat liver and kidney. Male Sprague-Dawley rats were treated with 0.21…”
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