Search Results - "Maguire, Alanna"
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What Does It Look Like, Sound Like and Feel Like? Shame and Identity in Mathematics Education
Published in Australian primary mathematics classroom (22-06-2021)“…Mathematics, when viewed as a subject to be studied, is a long-established polarising discipline; people's feelings are always passionate and deeply rooted in…”
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2
Clinical Impact of Immune Checkpoint Inhibitor (ICI) Response, DNA Damage Repair (DDR) Gene Mutations and Immune-Cell Infiltration in Metastatic Melanoma Subtypes
Published in Medical sciences (Basel) (24-05-2022)“…Molecular and histopathological analysis of melanoma subtypes has revealed distinct epidemiological, genetic, and clinical features. However, immunotherapy for…”
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3
Manual Construction of a Tissue Microarray using the Tape Method and a Handheld Microarrayer
Published in Journal of visualized experiments (10-06-2022)“…The tissue microarray (TMA) is an important research tool in which many formalin fixed paraffin embedded (FFPE) samples can be represented in a single paraffin…”
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4
Enhancing Tumor Content through Tumor Macrodissection
Published in Journal of visualized experiments (12-02-2022)“…The presence of contaminating non-tumor tissues in formalin-fixed paraffin-embedded (FFPE) tissues can greatly undermine genomic studies. Herein we describe…”
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Enhanced Genomic Stability in Monomorphic Post-Transplant Lymphoproliferative Disorders Is Driven By Distinct Mechanisms Stratified By EBV Status
Published in Blood (02-11-2023)“…Introduction: We previously showed that HIV associated EBV negative (-) diffuse large B-cell lymphomas (DLBCL) of germinal center origins (GCB) have enhanced…”
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6
Over-Expression of Transferrin Receptor (TFRC/CD71) and Low Expression of Innate and Adaptive Immune Cell Subsets in HIV-Associated, GCB-DLBCL By Digital Gene Expression Profiling
Published in Blood (13-11-2019)“…Introduction: HIV infected individuals are 17x more likely to receive a diagnosis of Diffuse Large B cell Lymphoma (DLBCL) compared to their uninfected…”
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Recommendations for Tissue Microarray Construction and Quality Assurance
Published in Applied immunohistochemistry & molecular morphology (01-04-2020)“…Tissue microarrays (TMAs) are important tools to conserve precious tissue resources from increasingly smaller biopsies and to control experimental costs and…”
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Genomic Stability, DNA Repair and the SKP1-CUL1-F-Box Complex in HIV Associated Diffuse Large B-Cell Lymphoma
Published in Blood (02-11-2023)“…Introduction: Previously we demonstrated that HIV associated diffuse large B-cell lymphomas (DLBCL) of Germinal Center B-cell subtype (GCB) are more…”
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Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV
Published in AIDS (London) (15-11-2020)“…OBJECTIVE:The increased risk for persons living with HIV to develop diffuse large B-cell lymphoma (DLBCL) even in the post-antiretroviral therapy eras suggests…”
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EBV‐positive HIV‐associated diffuse large B cell lymphomas are characterized by JAK/STAT (STAT3) pathway mutations and unique clinicopathologic features
Published in British journal of haematology (01-09-2021)“…Summary Even in the era of highly active combination antiretroviral therapy (cART), patients with HIV have a disproportionate risk of developing aggressive…”
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Enhanced Expression of FGF Signaling in Primary Central Nervous System Lymphoma
Published in Blood (29-11-2018)“…Introduction: Primary central nervous system lymphoma (PCNSL) is a rare intracranial lymphoma that accounts for less than 1% of all non-Hodgkins lymphomas and…”
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Clinical Features and Cell of Origin Subtyping Using Gene Expression Profiling in HIV-Negative Patients with Primary Central Nervous System Lymphoma
Published in Blood (29-11-2018)“…Objectives: Primary central nervous system lymphoma (PCNSL) is a rare aggressive B-cell lymphoma, particularly in HIV-negative individuals, that represents a…”
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Enhanced DNA repair and genomic stability identify a novel HIV‐related diffuse large B‐cell lymphoma signature
Published in International journal of cancer (01-12-2019)“…Diffuse large B‐cell lymphoma (DLBCL) is up to 17‐fold more likely to occur, follows a more aggressive clinical course and frequently presents at advanced…”
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14
Whole-exome sequencing of long-term, never relapse exceptional responders of trastuzumab-treated HER2+ metastatic breast cancer
Published in British journal of cancer (13-10-2020)“…Trastuzumab has significantly improved the overall survival of patients with HER2+ metastatic breast cancer (MBC). However, outcomes can vary, with patients…”
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Alternative signalling mechanisms to mediate Braf-Inhibitor resistance in isogenic primary and metastatic melanoma
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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16
Revolutions, Coups, and Clashes: Using Implicit Motivations to Predict the Severity of Intranational Political Unrest
Published in Peace and conflict (01-08-2014)“…Research has found that war is likely to break out in times when leaders are high in power motives and low in affiliation, however research has been limited to…”
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Assessment of 2-Year Storage Conditions on Protein, RNA, and DNA in Unstained Human Tissue Sections, Including a Novel Multiplex Digital Gene Expression Profiling Method with Implications for Biobanking
Published in Biopreservation and biobanking (01-12-2022)“…Formalin-fixed, paraffin-embedded (FFPE) tissues are a valuable resource for clinical and basic science research. Paraffin blocks and the resulting unstained…”
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Enhanced DNA Repair and Genomic Stability in HIV(+) Diffuse Large B Cell Lymphoma of Germinal Center Origin
Published in Blood (29-11-2018)“…Introduction: HIV infected individuals are 17x more likely to receive a diagnoses of Diffuse Large B cell Lymphoma (DLBCL) compared to their uninfected…”
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Genomic landscape of Epstein–Barr virus-positive extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue
Published in Modern pathology (01-07-2022)“…Epstein–Barr virus (EBV)-positive extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT lymphomas) were initially described in solid…”
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Profiling of lymphoma from formalin-fixed paraffin-embedded tissue
Published in Seminars in hematology (01-01-2019)“…Molecular profiling of lymphoma samples has contributed enormously to our understanding of disease biology leading to detailed descriptions of diagnostic…”
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