Search Results - "Magnuson, Victoria L"

Meta-Analysis of Vitamin D Receptor Polymorphisms and Type 1 Diabetes: A HuGE Review of Genetic Association Studies by Guo, Sun-Wei, Magnuson, Victoria L., Schiller, Jennifer J., Wang, Xujing, Wu, Yan, Ghosh, Soumitra

“…Several polymorphisms in the vitamin D receptor (VDR) gene have been reported to be associated with the risk of developing type 1 diabetes, yet published…”
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Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects by Klinker, Matthew W, Schiller, Jennifer J, Magnuson, Victoria L, Wang, Tao, Basken, Joel, Veth, Kerry, Pearce, Kaela I, Kinnunen, Leena, Harjutsalo, Valma, Wang, Xujing, Tuomilehto, Jaakko, Sarti, Cinzia, Ghosh, Soumitra

“…The onset of type 1 diabetes can occur at any age, with as many as half of all cases diagnosed after age 15. Despite this wide distribution in age at…”
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A Large Set of Finnish Affected Sibling Pair Families With Type 2 Diabetes Suggests Susceptibility Loci on Chromosomes 6, 11, and 14 by Silander, Kaisa, Scott, Laura J, Valle, Timo T, Mohlke, Karen L, Stringham, Heather M, Wiles, Kerry R, Duren, William L, Doheny, Kimberly F, Pugh, Elizabeth W, Chines, Peter, Narisu, Narisu, White, Peggy P, Fingerlin, Tasha E, Jackson, Anne U, Li, Chun, Ghosh, Soumitra, Magnuson, Victoria L, Colby, Kimberly, Erdos, Michael R, Hill, Jason E, Hollstein, Pablo, Humphreys, Kathleen M, Kasad, Roshni A, Lambert, Jessica, Lazaridis, Konstantinos N, Lin, George, Morales-Mena, Anabelle, Patzkowski, Kristin, Pfahl, Carrie, Porter, Rachel, Rha, David, Segal, Leonid, Suh, Yong D, Tovar, Jason, Unni, Arun, Welch, Christian, Douglas, Julie A, Epstein, Michael P, Hauser, Elizabeth R, Hagopian, William, Buchanan, Thomas A, Watanabe, Richard M, Bergman, Richard N, Tuomilehto, Jaakko, Collins, Francis S, Boehnke, Michael

“…A Large Set of Finnish Affected Sibling Pair Families With Type 2 Diabetes Suggests Susceptibility Loci on Chromosomes 6, 11, and 14 Kaisa Silander 1 , Laura…”
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Linkage disequilibrium between microsatellite markers extends beyond 1 cM on chromosome 20 in Finns by Mohlke, K L, Lange, E M, Valle, T T, Ghosh, S, Magnuson, V L, Silander, K, Watanabe, R M, Chines, P S, Bergman, R N, Tuomilehto, J, Collins, F S, Boehnke, M

“…Linkage disequilibrium (LD) is a proven tool for evaluating population structure and localizing genes for monogenic disorders. LD-based methods may also help…”
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Association of a polymorphism in the betacellulin gene with type 1 diabetes mellitus in two populations by Silver, Kristi D, Magnuson, Victoria L, Tolea, Magdalena, Wang, Jian, Hagopian, William A, Mitchell, Braxton D

“…Betacellulin, a member of the epidermal growth factor family, is expressed in fetal and adult pancreas. In vitro and in vivo studies suggest a role for…”
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Immunohistological localization of cell adhesion proteins and integrins in the periodontium by Steffensen, B, Duong, A H, Milam, S B, Potempa, C L, Winborn, W B, Magnuson, V L, Chen, D, Zardeneta, G, Klebe, R J

“…The distribution of the cell adhesion proteins vitronectin, fibronectin, tenascin, and laminin as well as several integrin subunits, alpha 2, alpha 5, and…”
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A Linkage Between DNA Markers on the X Chromosome and Male Sexual Orientation by Hamer, Dean H., Hu, Stella, Magnuson, Victoria L., Hu, Nan, Angela M. L. Pattatucci

“…The role of genetics in male sexual orientation was investigated by pedigree and linkage analyses on 114 families of homosexual men. Increased rates of…”
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Type 2 Diabetes: Evidence for Linkage on Chromosome 20 in 716 Finnish Affected Sib Pairs by Ghosh, Soumitra, Watanabe, Richard M., Hauser, Elizabeth R., Valle, Timo, Magnuson, Victoria L., Erdos, Michael R., Langefeld, Carl D., Balow, James, Ally, Delphine S., Kohtamaki, Kimmo, Chines, Peter, Birznieks, Gunther, Kaleta, Hong-Shi, Musick, Anjene, Te, Catherine, Tannenbaum, Joyce, Eldridge, William, Shapiro, Shane, Martin, Colin, Witt, Alyson, So, Alistair, Chang, Jennie, Shurtleff, Ben, Porter, Rachel, Kudelko, Kristina, Unni, Arun, Segal, Leonid, Sharaf, Ravi, Blaschak-Harvan, Jillian, Eriksson, Johan, Tenkula, Tuula, Vidgren, Gabriele, Ehnholm, Christian, Tuomilehto-Wolf, Eva, Hagopian, William, Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis S., Boehnke, Michael

“…We are conducting a genome scan at an average resolution of 10 centimorgans (cM) for type 2 diabetes susceptibility genes in 716 affected sib pairs from 477…”
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Genomic Data Mining to Narrow down Candidate Disease Genes for T1D by Xie, Yizhou, Laleli-Sahin, Elvan, Magnuson, Victoria L, Ghosh, Soumitra, Wang, Xujing

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Identify Candidate Disease Genes for Onset Delay of T1D Utilizing Mathematical Modeling and Bioinformatics by Xie, Yizhou, Khoo, Huoy-Jii, Laleli-Sahin, Elvan, Magnuson, Victoria L

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Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers by Ghosh, S, Karanjawala, ZE, Hauser, E R, Ally, D, Knapp, JI, Rayman, J B, Musick, A, Tannenbaum, J, Te, C

“…Large-scale genotyping is required to generate dense identity-by-descent maps to map genes for human complex disease. In some studies the number of genotypes…”
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Approach to genotyping errors caused by nontemplated nucleotide addition by Taq DNA polymerase by Smith, J R, Carpten, J D, Brownstein, M J, Ghosh, S, Magnuson, V L, Gilbert, D A, Trent, J M, Collins, F S

“…Thermostable DNA polymerases can catalyze nontemplated addition of a nucleotide to the 3' end of amplification products. This presents a potential source of…”
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The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors by MAGNUSON, V. L, YOUNG, M, SCHATTENBERG, D. G, MANCINI, M. A, CHEN, D, STEFFENSEN, B, KLEBE, R. J

“…The reverse transcription-polymerase chain reaction was used to examine alternative splicing at each of the three fibronectin exons known to undergo…”
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IL-1 beta and prostaglandins regulate integrin mRNA expression by Milam, S B, Magnuson, V L, Steffensen, B, Chen, D, Klebe, R J

“…The purpose of this study was to examine the effects of IL-1 beta on integrin expression in MG-63 human osteosarcoma cells. Human recombinant IL-1 beta (rIL-1…”
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A large sample of finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter by Ghosh, S, Hauser, E R, Magnuson, V L, Valle, T, Ally, D S, Karanjawala, Z E, Rayman, J B, Knapp, J I, Musick, A, Tannenbaum, J, Te, C, Eldridge, W, Shapiro, S, Musick, T, Martin, C, So, A, Witt, A, Harvan, J B, Watanabe, R M, Hagopian, W, Eriksson, J, Nylund, S J, Kohtamaki, K, Tuomilehto-Wolf, E, Boehnke, M

“…In the first reported positive result from a genome scan for non-insulin-dependent diabetes mellitus (NIDDM), Hanis et al. found significant evidence of…”
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Use of stock solutions to simplify mRNA quantitation by reverse transcription--PCR assays by Chen, D, Magnuson, V L, Steffensen, B, Klebe, R J

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The Finland–United States Investigation of Non–Insulin‐Dependent Diabetes Mellitus Genetics (FUSION) Study. I. An Autosomal Genome Scan for Genes That Predispose to Type 2 Diabetes by Ghosh, Soumitra, Watanabe, Richard M., Valle, Timo T., Hauser, Elizabeth R., Magnuson, Victoria L., Langefeld, Carl D., Ally, Delphine S., Mohlke, Karen L., Silander, Kaisa, Kohtamaki, Kimmo, Chines, Peter, Balow, Jr, James, Birznieks, Gunther, Chang, Jennie, Eldridge, William, Erdos, Michael R., Karanjawala, Zarir E., Knapp, Julie I., Kudelko, Kristina, Martin, Colin, Morales‐Mena, Anabelle, Musick, Anjene, Musick, Tiffany, Pfahl, Carrie, Porter, Rachel, Rayman, Joseph B., Rha, David, Segal, Leonid, Shapiro, Shane, Sharaf, Ravi, Shurtleff, Ben, So, Alistair, Tannenbaum, Joyce, Te, Catherine, Tovar, Jason, Unni, Arun, Welch, Christian, Whiten, Ray, Witt, Alyson, Blaschak‐Harvan, Jillian, Douglas, Julie A., Duren, William L., Epstein, Michael P., Fingerlin, Tasha E., Kaleta, Hong Shi, Lange, Ethan M., Li, Chun, McEachin, Richard C., Stringham, Heather M., Trager, Edward, White, Peggy P., Eriksson, Johan, Toivanen, Liisa, Vidgren, Gabriele, Nylund, Stella J., Tuomilehto‐Wolf, Eva, Ross, Edna H., Demirchyan, Elza, Hagopian, William A., Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis S., Boehnke, Michael

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The Finland–United States Investigation of Non–Insulin‐Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes‐Related Quantitative‐Trait Loci by Watanabe, Richard M., Ghosh, Soumitra, Langefeld, Carl D., Valle, Timo T., Hauser, Elizabeth R., Magnuson, Victoria L., Mohlke, Karen L., Silander, Kaisa, Ally, Delphine S., Chines, Peter, Blaschak‐Harvan, Jillian, Douglas, Julie A., Duren, William L., Epstein, Michael P., Fingerlin, Tasha E., Kaleta, Hong Shi, Lange, Ethan M., Li, Chun, McEachin, Richard C., Stringham, Heather M., Trager, Edward, White, Peggy P., Balow, Jr, James, Birznieks, Gunther, Chang, Jennie, Eldridge, William, Erdos, Michael R., Karanjawala, Zarir E., Knapp, Julie I., Kudelko, Kristina, Martin, Colin, Morales‐Mena, Anabelle, Musick, Anjene, Musick, Tiffany, Pfahl, Carrie, Porter, Rachel, Rayman, Joseph B., Rha, David, Segal, Leonid, Shapiro, Shane, Sharaf, Ravi, Shurtleff, Ben, So, Alistair, Tannenbaum, Joyce, Te, Catherine, Tovar, Jason, Unni, Arun, Welch, Christian, Whiten, Ray, Witt, Alyson, Kohtamaki, Kimmo, Ehnholm, Christian, Eriksson, Johan, Toivanen, Liisa, Vidgren, Gabriele, Nylund, Stella J., Tuomilehto‐Wolf, Eva, Ross, Edna H., Demirchyan, Elza, Hagopian, William A., Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis S., Boehnke, Michael

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Cultivation of mammalian cells in heat-sealable pouches that are permeable to carbon dioxide by Klebe, R J, Lyn, S, Magnuson, V L, Zardeneta, G

“…Petri plates, 96-well plates, and other unsealed culture vessels are the chief cause of air-borne contamination of cell cultures. In this study, heat-sealable…”
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Quantitative Assay for Morphogenesis Indicates the Role of Extracellular Matrix Components and G Proteins by Klebe, Robert J., Overfelt, Theodora M., Magnuson, Victoria L., Steffensen, Bjorn, Chen, Dali, Zardeneta, Gustavo

“…A quantitative assay for morphogenesis is described that involves counting the organizing centers (swirling patterns) formed by many cultured fibroblasts…”
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