Search Results - "Magnuson, Nancy S"

Trichomonosis, a common curable STI, and prostate carcinogenesis--a proposed molecular mechanism by Sutcliffe, Siobhan, Neace, Calvin, Magnuson, Nancy S, Reeves, Raymond, Alderete, J F

“…[...]as further epidemiologic evidence for an association between trichomonosis and prostate cancer risk, African Americans, who have the highest incidence of…”
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Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation by Din, Shabana, Mason, Matthew, Völkers, Mirko, Johnson, Bevan, Cottage, Christopher T., Wang, Zeping, Joyo, Anya Y., Quijada, Pearl, Erhardt, Peter, Magnuson, Nancy S., Konstandin, Mathias H., Sussman, Mark A.

“…Mitochondrial morphological dynamics affect the outcome of ischemic heart damage and pathogenesis. Recently, mitochondrial fission protein dynamin-related…”
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Why target PIM1 for cancer diagnosis and treatment? by Magnuson, Nancy S, Wang, Zeping, Ding, Gang, Reeves, Raymond

“…The highly conserved proto-oncogenic protein PIM1 is an unusual serine or threonine kinase, in part because it is constitutively active. Overexpression of PIM1…”
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HMGA1 Levels Influence Mitochondrial Function and Mitochondrial DNA Repair Efficiency by Mao, Li, Wertzler, Kelsey J., Maloney, Scott C., Wang, Zeping, Magnuson, Nancy S., Reeves, Raymond

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Pim-1 Kinase Stability Is Regulated by Heat Shock Proteins and the Ubiquitin-Proteasome Pathway by Shay, Kate Petersen, Wang, Zeping, Xing, Pei-Xiang, McKenzie, Ian F C, Magnuson, Nancy S

“…Elevated expression of the serine/threonine kinase Pim-1 increases the incidence of lymphomas in Pim-1 transgenic mice and has also been found to occur in some…”
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Dynamic mitochondrial localization of nuclear transcription factor HMGA1 by Dement, Gregory A., Treff, Nathan R., Magnuson, Nancy S., Franceschi, Vincent, Reeves, Raymond

“…It has been well established that high mobility group A1 (HMGA1) proteins act within the nucleus of mammalian cells as architectural transcription factors that…”
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Comparative understanding of UTS2 and UTS2R genes for their involvement in type 2 diabetes mellitus by Jiang, Zhihua, Michal, Jennifer J, Tobey, David J, Wang, Zeping, MacNeil, Michael D, Magnuson, Nancy S

“…Several reports have shown that urotensin 2 (UTS2) and its receptor (UTS2R) are involved in glucose metabolism and insulin resistance, which lead to…”
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Pim-1 Kinase-Dependent Phosphorylation of p21Cip1/WAF1 Regulates Its Stability and Cellular Localization in H1299 Cells by Zhang, Yandong, Wang, Zeping, Magnuson, Nancy S

“…Previous studies from our laboratory showed that p21 Cip1/WAF1 can be phosphorylated by Pim-1 kinase in vitro , implying that part of the function of Pim-1…”
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PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis by Hu, Xiu Feng, Li, Jie, Vandervalk, Scott, Wang, Zeping, Magnuson, Nancy S, Xing, Pei Xiang

“…Provirus integration site for Moloney murine leukemia virus (PIM1) is a proto-oncogene that encodes a serine/threonine kinase with multiple cellular functions…”
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novel type of sequence variation: multiple-nucleotide length polymorphisms discovered in the bovine genome by Jiang, Z, Wang, Z, Kunej, T, Williams, G.A, Michal, J.J, Wu, X.L, Magnuson, N.S

“…Three types of sequence variations--single-nucleotide polymorphisms (SNPs), insertions and deletions (indels), and short tandem repeats (STRs)--have been…”
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Pim-2 phosphorylation of p21(Cip1/WAF1) enhances its stability and inhibits cell proliferation in HCT116 cells by Wang, Zeping, Zhang, Yandong, Gu, Juan Jenny, Davitt, Christine, Reeves, Raymond, Magnuson, Nancy S

“…Pim-2 kinase is one of the three highly conserved Pim family members which are known to be involved in cell survival and cell proliferation. Here we…”
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Functional UQCRC1 Polymorphisms Affect Promoter Activity and Body Lipid Accumulation by Kunej, Tanja, Wang, Zeping, Michal, Jennifer J., Daniels, Tyler F., Magnuson, Nancy S., Jiang, Zhihua

“…Obesity and type 2 diabetes constitute leading public health problems worldwide. Studies have shown that insulin resistance affiliated with these conditions is…”
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Cellular automaton simulation examining progenitor hierarchy structure effects on mammary ductal carcinoma in situ by Bankhead, Armand, Magnuson, Nancy S., Heckendorn, Robert B.

“…A computer simulation is used to model ductal carcinoma in situ, a form of non-invasive breast cancer. The simulation uses known histological morphology, cell…”
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A single nucleotide polymorphism possibly associated with fat deposition is methylated in the bovine TFAM promoter by KUNEJ, Tanja, WANG, Zeping, MICHAL, Jennifer J., DOVČ, Peter, MAGNUSON, Nancy S., JIANG, Zhihua

“…Mitochondrial transcription factor A (TFAM) is a nuclear-encoded mitochondrial protein that plays an important role in energy metabolism and is a candidate…”
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Cryptic promoter activity in the DNA sequence corresponding to the pim-1 5′-UTR by Wang, Zeping, Weaver, Matt, Magnuson, Nancy S.

“…The serine/threonine kinase pim-1 mRNA contains a long and G/C rich 5′-untranslated region (5′-UTR). Previous work suggested that the pim-1 5′-UTR harbors an…”
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CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway by Zhu, Nongliao, Ramirez, Luis M, Lee, Rosaline L, Magnuson, Nancy S, Bishop, Gail A, Gold, Michael R

“…The ability of CD40 signaling to regulate B cell growth, survival, differentiation, and Ig class switching involves many changes in gene expression. Using cDNA…”
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Pim-1 kinase expression during murine mammary development by Gapter, Leslie A., Magnuson, Nancy S., Ng, Ka-yun, Hosick, Howard L.

“…Pim-1 kinase phosphorylates substrates whose activities are linked to proliferation, survival, differentiation, and apoptosis. Although pim-1 is induced by…”
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Pim-1 : A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis by Wang, Z, Bhattacharya, N, Weaver, M, Petersen, K, Meyer, M, Gapter, L, Magnuson, N S

“…Pim-1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified…”
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Pim-1 associates with protein complexes necessary for mitosis by Bhattacharya, Nandini, Wang, Zeping, Davitt, Christine, McKenzie, Ian F C, Xing, Pei-Xiang, Magnuson, Nancy S

“…The proto-oncogene pim-1 is a serine/threonine kinase the over-expression of which promotes lymphoma formation. Neither the normal function of Pim-1 nor the…”
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Secretion of Biologically Active Human Interleukin-2 and Interleukin-4 from Genetically Modified Tobacco Cells in Suspension Culture by Magnuson, Nancy S., Linzmaier, P.Michael, Reeves, Raymond, An, Gynheung, HayGlass, Kent, Lee, James M.

“…Biologically active human interleukin-2 (IL-2) and IL-4, key lymphokines involved in immune regulation, were produced and secreted into the medium by…”
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