Search Results - "Magnus, Gram"

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    Structure, Functions, and Physiological Roles of the Lipocalin α1-Microglobulin (A1M) by Bergwik, Jesper, Kristiansson, Amanda, Allhorn, Maria, Gram, Magnus, Åkerström, Bo

    Published in Frontiers in physiology (03-03-2021)
    “…α 1 -microglobulin (A1M) is found in all vertebrates including humans. A1M was, together with retinol-binding protein and β-lactoglobulin, one of the three…”
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    Journal Article
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    The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis—Therapeutic Opportunities in Hemolytic Conditions by Kristiansson, Amanda, Gram, Magnus, Flygare, Johan, Hansson, Stefan R., Åkerström, Bo, Storry, Jill R.

    “…α1-microglobulin (A1M) is a small protein present in vertebrates including humans. It has several physiologically relevant properties, including binding of…”
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    Journal Article
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    Red blood cell-derived arginase release in hemolytic uremic syndrome by Friberg, Niklas, Arvidsson, Ida, Tontanahal, Ashmita, Kristoffersson, Ann-Charlotte, Gram, Magnus, Kaplan, Bernard S, Karpman, Diana

    Published in Journal of translational medicine (04-01-2024)
    “…Hemolysis is a cardinal feature of hemolytic uremic syndrome (HUS) and during hemolysis excess arginase 1 is released from red blood cells. Increased arginase…”
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    Journal Article
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    Evaluation of recombinant human IGF-1/IGFBP-3 on intraventricular hemorrhage prevention and survival in the preterm rabbit pup model by Ekström, Claes, Ortenlöf, Niklas, Kristiansson, Amanda, Holmqvist, Bo, Jungner, Åsa, Vallius, Suvi, Wang, Xiaoyang, Hellström, Ann, Barton, Norman, Carey, Galen, Ley, David, Gram, Magnus

    Published in Scientific reports (13-11-2023)
    “…Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates processes of vascular maturation. The pathogenesis of…”
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    Journal Article
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    Effects of Recombinant α1-Microglobulin on Early Proteomic Response in Risk Organs after Exposure to 177Lu-Octreotate by Ytterbrink, Charlotte, Shubbar, Emman, Parris, Toshima Z., Langen, Britta, Druid, Malin, Schüler, Emil, Strand, Sven-Erik, Åkerström, Bo, Gram, Magnus, Helou, Khalil, Forssell-Aronsson, Eva

    “…Recombinant α1-microglobulin (A1M) is proposed as a protector during 177Lu-octreotate treatment of neuroendocrine tumors, which is currently limited by bone…”
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    Journal Article
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    α1-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro by Kristiansson, Amanda, Davidsson, Sara, Johansson, Maria E., Piel, Sarah, Elmér, Eskil, Hansson, Magnus J., Åkerström, Bo, Gram, Magnus

    “…Oxidative stress is associated with many renal disorders, both acute and chronic, and has also been described to contribute to the disease progression…”
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    Journal Article
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    Co-administration with A1M does not influence apoptotic response of 177Lu-octreotate in GOT1 neuroendocrine tumors by Rassol, Nishte, Andersson, Charlotte, Pettersson, Daniella, Al-Awar, Amin, Shubbar, Emman, Kovács, Anikó, Åkerström, Bo, Gram, Magnus, Helou, Khalil, Forssell-Aronsson, Eva

    Published in Scientific reports (19-04-2023)
    “…Recombinant α 1 -microglobulin (A1M) is a proposed radioprotector during 177 Lu-octreotate therapy of neuroendocrine tumors (NETs). To ensure a maintained…”
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    Journal Article
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    Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage by Gram, Magnus, Sveinsdottir, Snjolaug, Cinthio, Magnus, Sveinsdottir, Kristbjörg, Hansson, Stefan R, Mörgelin, Matthias, Åkerström, Bo, Ley, David

    Published in Journal of neuroinflammation (02-12-2014)
    “…Intraventricular hemorrhage (IVH) with post-hemorrhagic ventricular dilatation (PHVD) is a major cause of neurodevelopmental impairment and mortality in…”
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    Journal Article
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    Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture by Agyemang, Alex Adusei, Kvist, Suvi Vallius, Brinkman, Nathan, Gentinetta, Thomas, Illa, Miriam, Ortenlöf, Niklas, Holmqvist, Bo, Ley, David, Gram, Magnus

    Published in Journal of neuroinflammation (11-02-2021)
    “…Germinal matrix intraventricular hemorrhage (GM-IVH) is associated with deposition of redox active cell-free hemoglobin (Hb), derived from hemorrhagic…”
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    Journal Article
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    A1M, an extravascular tissue cleaning and housekeeping protein: a possible drug candidate by Magnus, Gram, Bo, Åkerström

    Published in Free Radical Biology and Medicine (01-10-2014)
    “…Alpha-1-microglobulin (A1M) is a small protein found intra- and extracellularly in all tissues of vertebrates. The protein was discovered 40 years ago and its…”
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    Journal Article Conference Proceeding
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    The Human Endogenous Protection System against Cell-Free Hemoglobin and Heme Is Overwhelmed in Preeclampsia and Provides Potential Biomarkers and Clinical Indicators by Gram, Magnus, Anderson, Ulrik Dolberg, Johansson, Maria E, Edström-Hägerwall, Anneli, Larsson, Irene, Jälmby, Maya, Hansson, Stefan R, Åkerström, Bo

    Published in PloS one (14-09-2015)
    “…Preeclampsia (PE) complicates 3-8% of all pregnancies and manifests clinically as hypertension and proteinuria in the second half of gestation. The…”
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    Journal Article
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    Heme: A link between hemorrhage and retinopathy of prematurity progression by Gáll, Tamás, Pethő, Dávid, Erdélyi, Katalin, Egri, Virág, Balla, Jázon György, Nagy, Annamária, Nagy, Annamária, Póliska, Szilárd, Gram, Magnus, Gábriel, Róbert, Nagy, Péter, Balla, József, Balla, György

    Published in Redox biology (01-10-2024)
    “…Neovascularization is implicated in the pathology of retinopathy of prematurity (ROP), diabetic retinopathy (DR), and age-related macular degeneration (AMD),…”
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    Journal Article
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