Search Results - "Magnotta, V"

Quantum chemical insight into the effects of the local electron environment on T2-based MRI by Petronek, M. S., St-Aubin, J. J., Lee, C. Y., Spitz, D. R., Gillan, E. G., Allen, B. G., Magnotta, V. A.

“…T 2 * relaxation is an intrinsic magnetic resonance imaging (MRI) parameter that is sensitive to local magnetic field inhomogeneities created by the deposition…”
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Iron-based biomarkers for personalizing pharmacological ascorbate therapy in glioblastoma: insights from a phase 2 clinical trial by Petronek, M. S., Bodeker, K. L., Lee, C. Y., Teferi, N., Eschbacher, K. L., Jones, K. A., Loeffler, B. T., Smith, B. J., Buatti, J. M., Magnotta, V. A., Allen, B. G.

“…Background Pharmacological ascorbate (intravenous delivery reaching plasma concentrations ≈ 20 mM; P-AscH − ) has emerged as a promising therapeutic strategy…”
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Quantum chemical insight into the effects of the local electron environment on T 2 -based MRI by Petronek, M S, St-Aubin, J J, Lee, C Y, Spitz, D R, Gillan, E G, Allen, B G, Magnotta, V A

“…T * relaxation is an intrinsic magnetic resonance imaging (MRI) parameter that is sensitive to local magnetic field inhomogeneities created by the deposition…”
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Brain abnormalities in bipolar disorder detected by quantitative T1ρ mapping by Johnson, C P, Follmer, R L, Oguz, I, Warren, L A, Christensen, G E, Fiedorowicz, J G, Magnotta, V A, Wemmie, J A

“…Abnormal metabolism has been reported in bipolar disorder, however, these studies have been limited to specific regions of the brain. To investigate…”
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Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate by Petronek, M.S., Teferi, N., Caster, J.M., Stolwijk, J.M., Zaher, A., Buatti, J.M., Hasan, D., Wafa, E.I., Salem, A.K., Gillan, E.G., St – Aubin, J.J., Buettner, G.R., Spitz, D.R., Magnotta, V.A., Allen, B.G.

“…Ferumoxytol (FMX) is an FDA-approved magnetite (Fe3O4) nanoparticle used to treat iron deficiency anemia that can also be used as an MR imaging agent in…”
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Global and regional cortical thinning in first-episode psychosis patients: relationships with clinical and cognitive features by Crespo-Facorro, B, Roiz-Santiáñez, R, Pérez-Iglesias, R, Rodriguez-Sanchez, J M, Mata, I, Tordesillas-Gutierrez, D, Sanchez, E, Tabarés-Seisdedos, R, Andreasen, N, Magnotta, V, Vázquez-Barquero, J L

“…The thickness of the cortical mantle is a sensitive measure for identifying alterations in cortical structure. We aimed to explore whether first episode…”
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Quantitative T1ρ mapping links the cerebellum and lithium use in bipolar disorder by Johnson, C P, Follmer, R L, Oguz, I, Warren, L A, Christensen, G E, Fiedorowicz, J G, Magnotta, V A, Wemmie, J A

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Voxel-based Morphometric Multisite Collaborative Study on Schizophrenia by Segall, Judith M., Turner, Jessica A., van Erp, Theo G.M., White, Tonya, Bockholt, H. Jeremy, Gollub, Randy L., Ho, Beng C., Magnotta, Vince, Jung, Rex E., McCarley, Robert W., Schulz, S. Charles, Lauriello, John, Clark, Vince P., Voyvodic, James T., Diaz, Michele T., Calhoun, Vince D.

“…Regional gray matter (GM) abnormalities are well known to exist in patients with chronic schizophrenia. Voxel-based morphometry (VBM) has been previously used…”
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Effects of olanzapine on cerebellar functional connectivity in schizophrenia measured by fMRI during a simple motor task by Stephan, K E, Magnotta, V A, White, T, Arndt, S, Flaum, M, O'Leary, D S, Andreasen, N C

“…According to current theories, schizophrenia results from altered connectivity in brain circuits for fundamental cognitive operations. Consequently, the poorly…”
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Longitudinal change in regional brain volumes in prodromal Huntington disease by Aylward, Elizabeth H, Nopoulos, Peggy C, Ross, Christopher A, Langbehn, Douglas R, Pierson, Ronald K, Mills, James A, Johnson, Hans J, Magnotta, Vincent A, Juhl, Andrew R, Paulsen, Jane S

“…ObjectiveAs therapeutics are being developed to target the underlying neuropathology of Huntington disease, interest is increasing in methodologies for…”
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Quantitative In Vivo Measurement of Gyrification in the Human Brain: Changes Associated with Aging by Magnotta, Vincent A., Andreasen, Nancy C., Schultz, Susan K., Harris, Greg, Cizadlo, Ted, Heckel, Dan, Nopoulos, Peg, Flaum, Michael

“…Clinical observation suggests that the aging process affects gyrification, with the brain appearing more ‘atrophic’ with increasing age. Empirical studies of…”
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Antipsychotic dose and diminished neural modulation: A multi-site fMRI study by Abbott, C., Juárez⁎, M., White, T., Gollub, R.L., Pearlson, G.D., Bustillo, J., Lauriello, J., Ho, B., Bockholt, H.J., Clark, V.P., Magnotta, V., Calhoun, V.D.

“…The effect of antipsychotics on the blood oxygen level dependent signal in schizophrenia is poorly understood. The purpose of the present investigation is to…”
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Hippocampal volume in chronic posttraumatic stress disorder (PTSD): MRI study using two different evaluation methods by Jatzko, A., Rothenhöfer, S., Schmitt, A., Gaser, C., Demirakca, T., Weber-Fahr, W., Wessa, M., Magnotta, V., Braus, D.F.

“…The hippocampus is discussed as one of the key regions in the pathogenesis of Posttraumatic Stress Disorder (PTSD). MRI results concerning the volume of the…”
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Improving tissue classification in MRI: A three-dimensional multispectral discriminant analysis method with Automated training class selection by HARRIS, G, ANDREASEN, N. C, CIZADLO, T, BAILEY, J. M, BOCKHOLT, H. J, MAGNOTTA, V. A, ARNDT, S

“…To improve the reliability, accuracy, and computational efficiency of tissue classification with multispectral sequences [T1, T2, and proton density (PD)], we…”
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Measurement of brain structures with artificial neural networks: two- and three-dimensional applications by Magnotta, V A, Heckel, D, Andreasen, N C, Cizadlo, T, Corson, P W, Ehrhardt, J C, Yuh, W T

“…To evaluate the ability of an artificial neural network (ANN) to identify brain structures. This ANN was applied to postprocessed magnetic resonance (MR)…”
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Global White Matter Abnormalities in Schizophrenia: A Multisite Diffusion Tensor Imaging Study by WHITE, Tonya, MAGNOTTA, Vincent A, LAURIELLO, John, BUSTILLO, Juan R, SCHULZ, S. Charles, GOLLUB, Randy L, ANDREASEN, Nancy C, CALHOUNO, Vince D, LIM, Kelvin O, BOCKHOLT, H. Jeremy, WILLIAMS, Sumner, WALLACE, Stuart, EHRLICH, Stefan, MUELLER, Bryon A, HO, Beng-Choon, JUNG, Rex E, CLARK, Vincent P

“…Emerging evidence implicates white matter (WM) abnormalities in the pathophysiology of schizophrenia. However, there is considerable heterogeneity in the…”
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Brain Structure in Preclinical Huntington’s Disease by Paulsen, Jane S., Magnotta, Vince A., Mikos, Ania E., Paulson, Henry L., Penziner, Elizabeth, Andreasen, Nancy C., Nopoulos, Peg C.

“…Huntington’s disease (HD) is traditionally conceptualized as a degenerative disease of the striatum. Recent scientific advances, however, have suggested…”
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A new method for the in vivo volumetric measurement of the human hippocampus with high neuroanatomical accuracy by Pantel, J., O'Leary, D. S., Cretsinger, K., Bockholt, H. J., Keefe, H., Magnotta, V. A., Andreasen, N. C.

“…Accurate and reproducible in vivo measurement of hippocampal volumes using magnetic resonance (MR) imaging is complicated by the morphological complexity of…”
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White matter integrity, as measured by diffusion tensor imaging, distinguishes between impaired and unimpaired older adult decision-makers: A preliminary investigation by Timpe, J. C., Rowe, K. C., Matsui, J., Magnotta, V. A., Denburg, N. L.

“…In the context of normal ageing, some individuals experience cognitive changes that affect their decision-making abilities. We investigated whether such…”
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Tumor perfusion studies using fast magnetic resonance imaging technique in advanced cervical cancer: a new noninvasive predictive assay by Mayr, N A, Yuh, W T, Magnotta, V A, Ehrhardt, J C, Wheeler, J A, Sorosky, J I, Davis, C S, Wen, B C, Martin, D D, Pelsang, R E, Buller, R E, Oberley, L W, Mellenberg, D E, Hussey, D H

“…This study investigated sequential changes in tumor blood supply using magnetic resonance (MR) perfusion imaging and assessed their significance in the…”
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