Search Results - "Magni, Ruben"
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Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread
Published in Retrovirology (23-02-2021)“…The Human T-cell Lymphotropic Virus Type-1 (HTLV-1) is a blood-borne pathogen and etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1…”
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Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma
Published in Acta neuropathologica communications (17-11-2023)“…Abstract Chemotherapy resistance is considered one of the main causes of tumor relapse, still challenging researchers for the identification of the molecular…”
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Author Correction: Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes
Published in Scientific reports (27-09-2021)Get full text
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Detection of toxoplasmic encephalitis in HIV positive patients in urine with hydrogel nanoparticles
Published in PLoS neglected tropical diseases (01-03-2021)“…Diagnosis of toxoplasmic encephalitis (TE) is challenging under the best clinical circumstances. The poor clinical sensitivity of quantitative polymerase chain…”
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Chemokine-Releasing Nanoparticles for Manipulation of Lymph Node Microenvironment
Published in Nanomaterials (Basel, Switzerland) (01-03-2015)“…Chemokines (CKs) secreted by the host cells into surrounding tissue establish concentration gradients directing the migration of leukocytes. We propose an CK…”
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Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…In the recent years, a lot of emphasis has been placed on the discovery and detection of clinically relevant biomarkers. Biomarkers are crucial for the early…”
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Analysis of the Babesia microti proteome in infected red blood cells by a combination of nanotechnology and mass spectrometry
Published in International journal for parasitology (01-02-2019)“…[Display omitted] •Babesiosis has been recognized as an emerging infectious disease in the United States.•Proteomic analysis of Babesia microti infection in…”
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Proteomic analysis reveals pathogen-derived biomarkers of acute babesiosis in erythrocytes, plasma, and urine of infected hamsters
Published in Parasitology research (1987) (01-07-2020)“…Babesiosis among humans is on the rise in North America. Current diagnostic assays for the screening of babesiosis require blood collection by venipuncture,…”
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Affinity enrichment for mass spectrometry: improving the yield of low abundance biomarkers
Published in Expert review of proteomics (03-04-2018)“…Mass spectrometry (MS) is the premier tool for discovering novel disease-associated protein biomarkers. Unfortunately, when applied to complex body fluid…”
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Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity
Published in Science translational medicine (13-12-2017)“…An accurate urine test for pulmonary tuberculosis (TB), affecting 9.6 million patients worldwide, is critically needed for surveillance and treatment…”
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A set of diagnostic tests for detection of active Babesia duncani infection
Published in International journal of infectious diseases (01-10-2024)“…•Developed enzyme-linked immunosorbent assays—Babesia duncani-specific antigen capture assays (BdACA)38 and BdACA234 to detect Babesia duncani, causing human…”
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Proteomic analysis of cerebrospinal fluid from children with central nervous system tumors identifies candidate proteins relating to tumor metastatic spread
Published in Oncotarget (11-07-2017)“…Central nervous system (CNS) tumors are the most common solid tumors in childhood. Since the sensitivity of combined cerebrospinal fluid (CSF) cytology and…”
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Evaluation of pathogen specific urinary peptides in tick-borne illnesses
Published in Scientific reports (09-11-2020)“…Mass spectrometry enhanced by nanotechnology can achieve previously unattainable sensitivity for characterizing urinary pathogen-derived peptides. We utilized…”
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Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis
Published in Journal of translational medicine (04-11-2015)“…Prompt antibiotic treatment of early stage Lyme borreliosis (LB) prevents progression to severe multisystem disease. There is a clinical need to improve the…”
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Abstract 1874: Investigation of the cerebrospinal fluid proteome from central nervous system pediatric tumors using bait loaded hydrogel nanoparticles and mass spectrometry
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract Central nervous system (CNS) tumors are the second common pediatric malignancies, accounting for approximately 25% of all childhood neoplasms…”
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Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes
Published in Scientific reports (18-08-2020)“…An accurate urine test for diverse populations with active tuberculosis could be transformative for preventing TB deaths. Urinary liporabinomannan (LAM)…”
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A tag-less method for direct isolation of human umbilical vein endothelial cells by gravitational field-flow fractionation
Published in Analytical and bioanalytical chemistry (01-01-2013)“…The analysis of cellular and molecular profiles represents a powerful tool in many biomedical applications to identify the mechanisms underlying the…”
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Hydrogel nanoparticle harvesting of plasma or urine for detecting low abundance proteins
Published in Journal of visualized experiments (07-08-2014)“…Novel biomarker discovery plays a crucial role in providing more sensitive and specific disease detection. Unfortunately many low-abundance biomarkers that…”
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Abstract 1080: Nanotechnology-enhanced proteomics analysis of a unique prospective collection of blood samples for the discovery and validation of early detection biomarkers for Non-Small Cell Lung Cancer (NSCLC)
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract BACKGROUND. Early identification of individuals at high risk to develop lung cancer would be a crucial requirement for a successful prevention…”
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