Search Results - "Maglathlin, Rebecca L"

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy by Golub, Todd R, Du, Jinyan, Bernasconi, Paula, Clauser, Karl R, Mani, D R, Finn, Stephen P, Beroukhim, Rameen, Burns, Melissa, Julian, Bina, Peng, Xiao P, Hieronymus, Haley, Maglathlin, Rebecca L, Lewis, Timothy A, Liau, Linda M, Nghiemphu, Phioanh, Mellinghoff, Ingo K, Louis, David N, Loda, Massimo, Carr, Steven A, Kung, Andrew L

“…The aberrant activation of tyrosine kinases represents an important oncogenic mechanism, and yet the majority of such events remain undiscovered. Here we…”
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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models by Sarkar, Sovan, Perlstein, Ethan O, Imarisio, Sara, Pineau, Sandra, Cordenier, Axelle, Maglathlin, Rebecca L, Webster, John A, Lewis, Timothy A, O'Kane, Cahir J, Schreiber, Stuart L, Rubinsztein, David C

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Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin by Fass, Daniel M, Shah, Rishita, Ghosh, Balaram, Hennig, Krista, Norton, Stephanie, Zhao, Wen-Ning, Reis, Surya A, Klein, Peter S, Mazitschek, Ralph, Maglathlin, Rebecca L, Lewis, Timothy A, Haggarty, Stephen J

“…Carboxylic acids with known central nervous system and histone deacetylase (HDAC) inhibitory activities were converted to hydroxamic acids and tested using a…”
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Powerful Combinatorial Screen to Identify High-Affinity Terbium(III)-Binding Peptides by Nitz, Mark, Franz, Katherine J, Maglathlin, Rebecca L, Imperiali, Barbara

“…Lanthanide-binding tags (LBTs) are protein fusion partners consisting of encoded amino acids that bind lanthanide ions with high affinity. Herein, we present a…”
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Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles by Serafimova, Iana M, Pufall, Miles A, Krishnan, Shyam, Duda, Katarzyna, Cohen, Michael S, Maglathlin, Rebecca L, McFarland, Jesse M, Miller, Rand M, Frödin, Morten, Taunton, Jack

“…A covalent inhibitor based on an electron-deficient olefin scaffold reversibly and selectively inhibits the p90 ribosomal protein S6 kinase RSK. Targeting…”
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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models by Schreiber, Stuart L, Rubinsztein, David C, Sarkar, Sovan, Perlstein, Ethan O, Imarisio, Sara, Pineau, Sandra, Cordenier, Axelle, Maglathlin, Rebecca L, Webster, John A, Lewis, Timothy A, O'Kane, Cahir J

“…The target of rapamycin proteins regulate various cellular processes including autophagy, which may play a protective role in certain neurodegenerative and…”
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Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis by Chou, Danny Hung-Chieh, Holson, Edward B., Wagner, Florence F., Tang, Alicia J., Maglathlin, Rebecca L., Lewis, Timothy A., Schreiber, Stuart L., Wagner, Bridget K.

“…Cytokine-induced beta-cell apoptosis is important to the etiology of type-1 diabetes. Although previous reports have shown that general inhibitors of histone…”
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Abstract 2635: Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum by Ruiz-Saenz, Ana, Sandhu, Manbir, Carrasco, Yazmin, Maglathlin, Rebecca L., Taunton, Jack, Moasser, Mark M.

“…Abstract There is increasing evidence implicating HER3 in several types of cancer, as a resilient copartner for HER2 in HER2-amplified cancers, and as a driver…”
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Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum by Ruiz-Saenz, A, Sandhu, M, Carrasco, Y, Maglathlin, R L, Taunton, J, Moasser, M M

“…There is increasing evidence implicating human epidermal growth factor receptor 3 (HER3) in several types of cancer. However, the development of targeted…”
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Toward drugging the translocon: sequence determinants and cellular consequences Sec61 inhibition by Maglathlin, Rebecca L

“…Secretory and membrane proteins (secretory proteins) are the conduits through which cells communicate. Membrane proteins make up 35% of the human genome and,…”
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Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin by Fass, Daniel M, Shah, Rishita, Ghosh, Balaram, Hennig, Krista, Norton, Stephanie, Zhao, Wen-Ning, Reis, Surya A, Klein, Peter S, Mazitschek, Ralph, Maglathlin, Rebecca L, Lewis, Timothy A, Haggarty, Stephen J

“…Carboxylic acids with known central nervous system and histone deacetylase (HDAC) inhibitory activities were converted to hydroxamic acids and tested using a…”
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Cover Picture: A Powerful Combinatorial Screen to Identify High-Affinity Terbium(III)-Binding Peptides (ChemBioChem 4/2003) by Nitz, Mark, Franz, Katherine J., Maglathlin, Rebecca L., Imperiali, Barbara

“…Abstract The cover picture shows the chemistry and biology used to develop a new protein labeling strategy based on lanthanide‐binding peptides. Focused…”
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