Search Results - "Magistretti, P.J."

S.04.01 Role of neuron-glia metabolic coupling in neuronal plasticity by Magistretti, P.J

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Regulation of neuron–astrocyte metabolic coupling across the sleep–wake cycle by Petit, J.-M, Magistretti, P.J

“…Highlights • Astrocytes adjust local energy production to neuronal energy needs. • The “neurometabolic coupling” (NMC) mechanisms interact with sleep…”
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Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling by Zeis, T, Allaman, I, Gentner, M, Schroder, K, Tschopp, J, Magistretti, P.J, Schaeren-Wiemers, N

“…Highlights • Astrocytic ANLS and GGC genes are downregulated in MS gray matter tissue. • MS NAGM gene expression is indicative of active Toll-like/IL-1B…”
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S46-3 Neuron-glia metabolic coupling and plasticity by Magistretti, P.J

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P.4.004 A key role of astrocytic lactate in the formation and maintenance of memories associated with cocaine-associated cues by Jamot, B. Boury, Carrard, A, Martin, J.L, Halfon, O, Magistretti, P.J, Boutrel, B

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Distribution of Aquaporin 9 in the adult rat brain: Preferential expression in catecholaminergic neurons and in glial cells by Badaut, J., Petit, J.-M., Brunet, J.-F., Magistretti, P.J., Charriaut-Marlangue, C., Regli, L.

“…Aquaporin 9 (AQP9) is a recently cloned water channel that is permeable to monocarboxylate, glycerol and urea. In rat, AQP9 has been found in testis and liver…”
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Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy by Pierre, K, Pellerin, L, Debernardi, R, Riederer, B.M, Magistretti, P.J

“…Recent evidence suggests that lactate could be a preferential energy substrate transferred from astrocytes to neurons. This would imply the presence of…”
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Induction of brain aquaporin 9 (AQP9) in catecholaminergic neurons in diabetic rats by Badaut, J, Brunet, J.F, Petit, J.-M, Guérin, C.F, Magistretti, P.J, Regli, L

“…Abstract Aquaporin 9 facilitates the diffusion of water but also glycerol and monocarboxylates, known as brain energy substrates. AQP9 was recently observed in…”
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Glucose and lactate are equally effective in energizing activity-dependent synaptic vesicle turnover in purified cortical neurons by Morgenthaler, F.D., Kraftsik, R., Catsicas, S., Magistretti, P.J., Chatton, J.-Y.

“…This study examines the role of glucose and lactate as energy substrates to sustain synaptic vesicle cycling. Synaptic vesicle turnover was assessed in a…”
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Differential messenger RNA distribution of lactate dehydrogenase LDH-1 and LDH-5 isoforms in the rat brain by Laughton, J.D., Charnay, Y., Belloir, B., Pellerin, L., Magistretti, P.J., Bouras, C.

“…The role of lactate in brain energy metabolism has recently received renewed attention. Although blood-borne monocarboxylates such as lactate poorly cross the…”
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Disrupting astrocyte–neuron lactate transfer persistently reduces conditioned responses to cocaine by Boury-Jamot, B, Carrard, A, Martin, J L, Halfon, O, Magistretti, P J, Boutrel, B

“…A central problem in the treatment of drug addiction is the high risk of relapse often precipitated by drug-associated cues. The transfer of glycogen-derived…”
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Exploring neural cell dynamics with digital holographic microscopy by Marquet, P, Depeursinge, C, Magistretti, P J

“…In this review, we summarize how the new concept of digital optics applied to the field of holographic microscopy has allowed the development of a reliable and…”
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New insights into the “Glycogenetic” hypothesis of sleep: brain glycogen availability affects REM-related theta rhythm providing a possible link with emotional memory mechanisms by Burlet-Godinot, S., Petit, J.-M., Roach, P.J., Depaoli-Roach, A.A., Magistretti, P.J.

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Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection by Jourdain, P., Rothenfusser, K., Ben-Adiba, C., Allaman, I., Marquet, P., Magistretti, P. J.

“…L-Lactate is a positive modulator of NMDAR-mediated signaling resulting in plasticity gene induction and memory consolidation. However, L-Lactate is also able…”
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Functional consequences of brain glycogen deficiency on the sleep-wake cycle regulation in PTG-KO mice by Burlet-Godinot, S., Allaman, I., Grenningloh, G., Roach, P.J., Depaoli-Roach, A.A., Magistretti, P.J., Petit, J.-M.

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Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes by Ruchti, E., Roach, P.J., DePaoli-Roach, A.A., Magistretti, P.J., Allaman, I.

“…The storage and use of glycogen, the main energy reserve in the brain, is a metabolic feature of astrocytes. Glycogen synthesis is regulated by Protein…”
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The distribution and morphological characteristics of the intracortical VIP-positive cell: an immunohistochemical analysis by Morrison, J H, Magistretti, P J, Benoit, R, Bloom, F E

“…Using a sensitive immunohistochemical procedure, we have undertaken a detailed morphological characterization of the vasoactive intestinal peptide-positive…”
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Autoradiographic mapping of [mono[125I]iodo-Tyr10, MetO17]vasoactive intestinal peptide binding sites in the rat brain by Martin, J L, Dietl, M M, Hof, P R, Palacios, J M, Magistretti, P J

“…The distribution of vasoactive intestinal peptide binding sites in the rat brain was examined by in vitro autoradiography on slide-mounted sections. A fully…”
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Evidence for a Susceptibility Gene for Anorexia Nervosa on Chromosome 1 by Grice, D.E., Halmi, K.A., Fichter, M.M., Strober, M., Woodside, D.B., Treasure, J.T., Kaplan, A.S., Magistretti, P.J., Goldman, D., Bulik, C.M., Kaye, W.H., Berrettini, W.H.

“…Eating disorders, such as anorexia nervosa (AN), have a significant genetic component. In the current study, a genomewide linkage analysis of 192 families with…”
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Astrocytes and brain energy metabolism: Possible influence on eating behavior by Magistretti, P.J.

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