Search Results - "Magilavy, Daniel B"

An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis by Weinblatt, Michael E, Kavanaugh, Arthur, Genovese, Mark C, Musser, Theresa K, Grossbard, Elliott B, Magilavy, Daniel B

“…Spleen tyrosine kinase (Syk) is an important modulator of immune signaling. In this randomized trial involving patients with active rheumatoid arthritis, there…”
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An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: A three‐month randomized, placebo‐controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agents by Genovese, Mark C., Kavanaugh, Arthur, Weinblatt, Michael E., Peterfy, Charles, DiCarlo, Julie, White, Michael L., O'Brien, Maryann, Grossbard, Elliott B., Magilavy, Daniel B.

“…Objective To assess the efficacy and safety of R788 (fostamatinib disodium), an inhibitor of spleen tyrosine kinase (Syk), in patients with active rheumatoid…”
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Effects of Fostamatinib (R788), an Oral Spleen Tyrosine Kinase Inhibitor, on Health-related Quality of Life in Patients with Active Rheumatoid Arthritis: Analyses of Patient-reported Outcomes from a Randomized, Double-blind, Placebo-controlled Trial by WEINBLATT, Michael E, KAVANAUGH, Arthur, GENOVESE, Mark C, JONES, David A, MUSSER, Theresa K, GROSSBARD, Elliott B, MAGILAVY, Daniel B

“…To assess the influence of fostamatinib on patient-reported outcomes (PRO) in patients with active rheumatoid arthritis and an inadequate response to…”
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An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis by WEINBLATT, Michael E, KAVANAUGH, Arthur, GENOVESE, Mark C, MUSSER, Theresa K, GROSSBARD, Elliott B, MAGILAVY, Daniel B

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Hylan G-F 20 improves hip osteoarthritis: a prospective, randomized study by Spitzer, Andrew I, Bockow, Barry I, Brander, Victoria A, Yates, James W, MacCarter, Daryl K, Gudger, Garland K, Haller, Stephanie, Lake, Stephen L, Magilavy, Daniel B

“…We compared the efficacy and safety of intra-articular hylan G-F 20 with methylprednisolone acetate (MPA) for treating symptomatic Kellgren-Lawrence grade…”
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Pseudoseptic reactions to Hylan viscosupplementation: diagnosis and treatment by Magilavy, Daniel B, McPherson, John M, Polisson, Richard

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Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis by Otón, Teresa, Silva-Fernández, Lucía, Andreu, José Luis, Okamoto, Hiroshi, Kobayashi, Akiko, Weinblatt, Michael E, Grossbard, Elliot B, Magilavy, Daniel B

“…To the Editor: Weinblatt et al. (Sept. 30 issue) 1 report on the safety and efficacy of an oral spleen tyrosine kinase (Syk) inhibitor in active rheumatoid…”
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Effects of methotrexate on radiologic progression in juvenile rheumatoid arthritis by Harel, L, Wagner-Weiner, L, Poznanski, A K, Spencer, C H, Ekwo, E, Magilavy, D B

“…To assess the effects of methotrexate (MTX) therapy on radiologic progression in juvenile rheumatoid arthritis (JRA). We evaluated serial wrist radiographs for…”
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Intermittent intravenous cyclophosphamide therapy for lupus nephritis by Lehman, T J, Sherry, D D, Wagner-Weiner, L, McCurdy, D K, Emery, H M, Magilavy, D B, Kovalesky, A

“…We carried out a preliminary study to determine whether intermittent intravenous cyclophosphamide therapy could be safely and effectively used in the treatment…”
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Animal models of chronic inflammatory arthritis by Magilavy, D B

“…The use of animals has been indispensable to the investigation of the etiology, pathophysiology, and treatment of juvenile arthritis. Because of ethical…”
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Liver of MRL/lpr mice contain interleukin-4-producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones by Magilavy, D B, Foys, K M, Gajewski, T F

“…Hepatic nonparenchymal cells (NPC) from mice of nonautoimmune strains support the proliferation of only Th1 and not Th2 helper T lymphocyte (HTL) clones…”
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The liver of MRL/lpr mice contains defective accessory cells and a population of immunosuppressive lymphocytes by Magilavy, D B, Rowley, D A, Davis, M

“…Immunoregulatory abnormalities in the MRL/lpr mouse strain include activation of macrophages and hepatic natural killer cells, spontaneous production of tumor…”
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Lymphocyte Ecto-5′-Nucleotidase Deficiency in Agammaglobulinemia by Edwards, N. Lawrence, Magilavy, Daniel B., Cassidy, James T., Fox, Irving H.

“…Fresh peripheral blood lymphocytes from eight patients with congenital agammaglobulinemia demonstrate reduced ecto-5′-nucleotidase activity when compared to…”
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High hepatic natural killer cell activity in murine lupus by MAGILAVY, D. B, STEINBERG, A. D, LATTA, S. L

“…This study demonstrates a profound elevation of NK activity, as measured by cytotoxicity to YAC-1 targets in a 4-h incubation 51Cr-release assay, of freshly…”
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Immune abnormalities in the pathogenesis of juvenile rheumatoid arthritis by Lipnick, R N, Tsokos, G C, Magilavy, D B

“…Juvenile rheumatoid arthritis (JRA) is the most common rheumatic disease of childhood. Although the etiology remains unknown, immunoregulatory imbalances are…”
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Pulmonary hemorrhage in pediatric patients with systemic lupus erythematosus by Miller, R W, Salcedo, J R, Fink, R J, Murphy, T M, Magilavy, D B

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The autoimmune disease systemic lupus erythematosus is not associated with left-handedness by Salcedo, J R, Spiegler, B J, Gibson, E, Magilavy, D B

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Pediatric rheumatology manpower and training: planning for the 1990s by LEHMAN, T. J. A, MAGILAVY, D. V, WARREN, R

“…According to recent estimates, 350 000 children each year will experience an acute episode of joint pain, and nearly 200 000 will have juvenile rheumatoid…”
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Mucocutaneous lymph node syndrome: report of two cases complicated by gallbladder hydrops and diagnosed by ultrasound by Magilavy, D B, Speert, D P, Silver, T M, Sullivan, D B

“…Two patients with mucocutaneous lymph node syndrome are presented. During the course of their illnesses, they developed acute abdominal pain secondary to…”
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A syndrome of childhood polyarteritis by Magilavy, D B, Petty, R E, Cassidy, J T, Sullivan, D B

“…In this report the clinical, laboratory, and histopathologic findings of nine children with polyarteritis are reviewed. All have had evidence of systemic…”
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