Search Results - "Magid, Michal"

Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations by Mayhew, David, Devos, Nathalie, Lambert, Christophe, Brown, James R, Clarke, Stuart C, Kim, Viktoriya L, Magid-Slav, Michal, Miller, Bruce E, Ostridge, Kristoffer K, Patel, Ruchi, Sathe, Ganesh, Simola, Daniel F, Staples, Karl J, Sung, Ruby, Tal-Singer, Ruth, Tuck, Andrew C, Van Horn, Stephanie, Weynants, Vincent, Williams, Nicholas P, Devaster, Jeanne-Marie, Wilkinson, Tom M A

“…Alterations in the composition of the lung microbiome associated with adverse clinical outcomes, known as dysbiosis, have been implicated with disease severity…”
Get more information

Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C by McKnight, Kevin L., Swanson, Karen V., Austgen, Kathryn, Richards, Cindy, Mitchell, Jonathan K., McGivern, David R., Fritch, Ethan, Johnson, John, Remlinger, Katja, Magid-Slav, Michal, Kapustina, Maryna, You, Shihyun, Lemon, Stanley M.

“…Human rhinoviruses (RVs) are positive-strand RNA viruses that cause respiratory tract disease in children and adults. Here we show that the innate immune…”
Get full text

Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4 by Peled, Amnon, Petit, Isabelle, Kollet, Orit, Magid, Michal, Ponomaryov, Tanya, Byk, Tamara, Nagler, Arnon, Ben-Hur, Herzl, Many, Ariel, Shultz, Leonard, Lider, Ofer, Alon, Ronen, Zipori, Dov, Lapidot, Tsvee

“…Stem cell homing and repopulation are not well understood. The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 were found to be critical…”
Get full text

Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis by Smith, Steven B, Dampier, William, Tozeren, Aydin, Brown, James R, Magid-Slav, Michal

“…Pandemic and seasonal respiratory viruses are a major global health concern. Given the genetic diversity of respiratory viruses and the emergence of drug…”
Get full text

Host response to respiratory bacterial pathogens as identified by integrated analysis of human gene expression data by Smith, Steven B, Magid-Slav, Michal, Brown, James R

“…Respiratory bacterial pathogens are one of the leading causes of infectious death in the world and a major health concern complicated by the rise of…”
Get full text

Immature Leukemic CD34+CXCR4+ Cells from CML Patients Have Lower Integrin‐Dependent Migration and Adhesion in Response to the Chemokine SDF‐1 by Peled, Amnon, Hardan, Izhar, Trakhtenbrot, Luba, Gur, Eyal, Magid, Michal, Darash‐Yahana, Merav, Cohen, Ninette, Grabovsky, Valentin, Franitza, Suzana, Kollet, Orit, Lider, Ofer, Alon, Ronen, Rechavi, Gideon, Lapidot, Tsvee

“…Chronic myelogenous leukemia (CML), a malignant myeloproliferative disorder originating from a pluripotent stem cell expressing the bcr‐abl oncogene, is…”
Get full text

The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34+ cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice by Peled, Amnon, Kollet, Orit, Ponomaryov, Tanya, Petit, Isabelle, Franitza, Suzanna, Grabovsky, Valentin, Slav, Michal Magid, Nagler, Arnon, Lider, Ofer, Alon, Ronen, Zipori, Dov, Lapidot, Tsvee

“…Hematopoietic stem cell homing and engraftment require several adhesion interactions, which are not fully understood. Engraftment of nonobese/severe combined…”
Get full text

The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34+ cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice by Peled, Amnon, Kollet, Orit, Ponomaryov, Tanya, Petit, Isabelle, Franitza, Suzanna, Grabovsky, Valentin, Slav, Michal Magid, Nagler, Arnon, Lider, Ofer, Alon, Ronen, Zipori, Dov, Lapidot, Tsvee

“…Hematopoietic stem cell homing and engraftment require several adhesion interactions, which are not fully understood. Engraftment of nonobese/severe combined…”
Get full text

More than just innate immunity: comparative analysis of Chlamydophila pneumoniae and Chlamydia trachomatis effects on host‐cell gene regulation by Hess, Simone, Peters, Jan, Bartling, Gerda, Rheinheimer, Claudia, Hegde, Priti, Magid‐Slav, Michal, Tal‐Singer, Ruth, Klos, Andreas

“…Summary Chlamydophila pneumoniae and Chlamydia trachomatis cause infections of the respiratory or urogenital tract. In addition, both species have been…”
Get full text

Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets by Wang, Zhang, Arat, Seda, Magid-Slav, Michal, Brown, James R

“…With the global emergence of multi-drug resistant strains of Mycobacterium tuberculosis, new strategies to treat tuberculosis are urgently needed such as…”
Get full text

Pathway analysis of GWAS loci identifies novel drug targets and repurposing opportunities by Jhamb, Deepali, Magid-Slav, Michal, Hurle, Mark R., Agarwal, Pankaj

“…•Pathway analysis of GWAS loci identifies novel drug targets and repurposing opportunities.•Global systematic analysis of 1,589 GWAS across 1,456 protein…”
Get full text

Diagnostic Performance of Traditional Hepatobiliary Biomarkers of Drug-Induced Liver Injury in the Rat by Ennulat, Daniela, Magid-Slav, Michal, Rehm, Sabine, Tatsuoka, Kay S.

“…Nonclinical studies provide the opportunity to anchor biochemical with morphologic findings; however, liver injury is often complex and heterogeneous,…”
Get full text

Effects of Hepatic Drug-metabolizing Enzyme Induction on Clinical Pathology Parameters in Animals and Man by Ennulat, Daniela, Walker, Dana, Clemo, Frances, Magid-Slav, Michal, Ledieu, David, Graham, Mark, Botts, Suzanne, Boone, Laura

“…Hepatic drug-metabolizing enzyme (DME) induction is an adaptive response associated with changes in preclinical species; this response can include increases in…”
Get full text

Computational biology approaches for selecting host–pathogen drug targets by Brown, James R., Magid-Slav, Michal, Sanseau, Philippe, Rajpal, Deepak K.

“…The proliferation of genomic platform data, ranging from silencing RNAs through mRNA and microRNA expression to proteomics, is providing new insights into the…”
Get full text

Gastrointestinal weight-loss surgery: glimpses at the molecular level by Freudenberg, Johannes M., Rajpal, Neetu, Way, James M., Magid-Slav, Michal, Rajpal, Deepak K.

“…► Molecular data analysis of gastro-intestinal weight-loss surgery. ► Integrated informatics strategy with pre- and post- weight-loss surgery datasets. ►…”
Get full text

Potential candidate genomic biomarkers of drug induced vascular injury in the rat by Dalmas, Deidre A., Scicchitano, Marshall S., Mullins, David, Hughes-Earle, Angela, Tatsuoka, Kay, Magid-Slav, Michal, Frazier, Kendall S., Thomas, Heath C.

“…Drug-induced vascular injury is frequently observed in rats but the relevance and translation to humans present a hurdle for drug development. Numerous…”
Get full text

Host Response to Respiratory Bacterial Pathogens as Identified by Integrated Analysis of Human Gene Expression Data: e75607 by Smith, Steven B, Magid-Slav, Michal, Brown, James R

“…Respiratory bacterial pathogens are one of the leading causes of infectious death in the world and a major health concern complicated by the rise of…”
Get full text

Molecular evolutionary analysis of cancer cell lines by Zhang, Yan, Italia, Michael J, Auger, Kurt R, Halsey, Wendy S, Van Horn, Stephanie F, Sathe, Ganesh M, Magid-Slav, Michal, Brown, James R, Holbrook, Joanna D

“…With genome-wide cancer studies producing large DNA sequence data sets, novel computational approaches toward better understanding the role of mutations in…”
Get full text