Search Results - "Maggioncalda, Emily C."
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A mouse model of pulmonary Mycobacteroides abscessus infection
Published in Scientific reports (28-02-2020)“…There is no preclinical mouse model to investigate pulmonary Mycobacteroides abscessus (formerly Mycobacterium abscessus ) infection in an immunocompetent…”
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Mycobacterium abscessus and β-Lactams: Emerging Insights and Potential Opportunities
Published in Frontiers in microbiology (25-09-2018)“…β-lactams, the most widely used class of antibiotics, are well-tolerated, and their molecular mechanisms of action against many bacteria are well-documented. (…”
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Development of a penem antibiotic against Mycobacteroides abscessus
Published in Communications biology (07-12-2020)“…β-lactams are the most widely used antibiotic class to treat bacterial infections in humans. Mycobacteroides abscessus is an emerging pulmonary pathogen…”
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Select β-Lactam Combinations Exhibit Synergy against Mycobacterium abscessus In Vitro
Published in Antimicrobial agents and chemotherapy (01-04-2019)“…is a nontuberculous mycobacterium that causes invasive pulmonary infections in patients with structural lung disease. is intrinsically resistant to several…”
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Synergistic Efficacy of β-Lactam Combinations against Mycobacterium abscessus Pulmonary Infection in Mice
Published in Antimicrobial agents and chemotherapy (01-08-2019)“…is an emerging pathogen capable of causing invasive pulmonary infections in patients with chronic lung diseases. These infections are difficult to treat,…”
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Glby, Encoded by MAB_3167c , Is Required for In Vivo Growth of Mycobacteroides abscessus and Exhibits Mild β-Lactamase Activity
Published in Journal of bacteriology (17-05-2022)“…Mycobacteroides abscessus ( ; also known as Mycobacterium abscessus) is an emerging opportunistic pathogen. Patients with structural lung conditions such as…”
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Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates In Vitro and in a Mouse Model of Pulmonary Infection
Published in Antimicrobial agents and chemotherapy (18-01-2022)“…The incidence of nontuberculous mycobacterial diseases in the United States is rising and has surpassed that of tuberculosis. Most notable among the…”
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Clofazimine as a comparator for preclinical efficacy evaluations of experimental therapeutics against pulmonary M. abscessus infection in mice
Published in Tuberculosis (Edinburgh, Scotland) (01-12-2022)“…Mycobacteroides abscessus (Mab, also known as Mycobacterium abscessus) can cause chronic pulmonary disease in the setting of structural lung conditions…”
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Structure–Activity Relationship of Penem Antibiotic Side Chains Used against Mycobacteria Reveals Highly Active Compounds
Published in ACS infectious diseases (12-08-2022)“…The rise of antibiotic-resistant Mycobacterium tuberculosis and non-tuberculous mycobacterial infections has placed ever-increasing importance on discovering…”
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290. Prediction of Severe Clostridioides difficile Infection Using Isolate Genomic Variation Influenced by Patient Comorbidity Score
Published in Open forum infectious diseases (27-11-2023)Get full text
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