Search Results - "Maggi, Lauretta"
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Hybrid Nanocomposites of Tenoxicam: Layered Double Hydroxides (LDHs) vs. Hydroxyapatite (HAP) Inorganic Carriers
Published in Molecules (Basel, Switzerland) (11-05-2023)“…The search for effective systems to facilitate the release of poorly bioavailable drugs is a forefront topic for the pharmaceutical market. Materials…”
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2
Physicochemical Characterization of Hydroxyapatite Hybrids with Meloxicam for Dissolution Rate Improvement
Published in Molecules (Basel, Switzerland) (21-05-2024)“…Organic-inorganic hybrids represent a good solution to improve the solubility and dissolution rates of poorly soluble drugs whose number has been increasing in…”
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3
N-acetylcysteine (NAC) and Its Role in Clinical Practice Management of Cystic Fibrosis (CF): A Review
Published in Pharmaceuticals (Basel, Switzerland) (11-02-2022)“…N-acetylcysteine is the acetylated form of the amino acid L-cysteine and a precursor to glutathione (GSH). It has been known for a long time as a powerful…”
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4
Synthesis and Characterization of Carvedilol-Etched Halloysite Nanotubes Composites with Enhanced Drug Solubility and Dissolution Rate
Published in Molecules (Basel, Switzerland) (01-04-2023)“…Carvedilol is a poorly water-soluble drug employed to treat chronic heart failure. In this study, we synthesize new carvedilol-etched halloysite nanotubes…”
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5
Tablet Formulations of Polymeric Electrospun Fibers for the Controlled Release of Drugs with pH-Dependent Solubility
Published in Polymers (23-05-2022)“…A challenge in the pharmaceutical sector is the development of controlled release dosage forms for oral administration of poorly soluble drugs, in particular,…”
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Improvement of the Firocoxib Dissolution Performance Using Electrospun Fibers Obtained from Different Polymer/Surfactant Associations
Published in International journal of molecular sciences (24-06-2019)“…An electrospinning process was optimized to produce fibers of micrometric size with different combinations of polymeric and surfactant materials to promote the…”
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7
Probenecid and benzamide: DSC applied to the study of an “impossible” pharmaceutical system
Published in Journal of thermal analysis and calorimetry (01-07-2021)“…The study of the binary system probenecid–benzamide is an excellent example of the power and the limits of thermal analysis applied to the investigations of…”
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8
New Emerging Inorganic–Organic Systems for Drug-Delivery: Hydroxyapatite@Furosemide Hybrids
Published in Journal of inorganic and organometallic polymers and materials (2022)“…In the pharmaceutical market, the need to find effective systems for the efficient release of poorly bioavailable drugs is a forefront topic. The…”
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9
Hydroxyapatite Nanorods Based Drug Delivery Systems for Bumetanide and Meloxicam, Poorly Water Soluble Active Principles
Published in Nanomaterials (Basel, Switzerland) (01-01-2024)“…Poorly water-soluble drugs represent a challenge for the pharmaceutical industry because it is necessary to find properly tuned and efficient systems for their…”
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10
Design of Etched- and Functionalized-Halloysite/Meloxicam Hybrids: A Tool for Enhancing Drug Solubility and Dissolution Rate
Published in Pharmaceutics (28-02-2024)“…The study focuses on the synthesis and characterization of Meloxicam-halloysite nanotube (HNT) composites as a viable approach to enhance the solubility and…”
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11
Meloxicam-LDH Hybrid Compound: A Successful Strategy to Improve Solubility
Published in Journal of inorganic and organometallic polymers and materials (01-03-2020)“…The use of nanohybrids containing cationic or anionic inorganic compounds, seems particularly promising as efficient strategy for drug delivery. In fact, the…”
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12
Probenecid and benzamide: cocrystal prepared by a green method and its physico-chemical and pharmaceutical characterization
Published in Journal of thermal analysis and calorimetry (01-05-2020)“…The eco-friendly method of kneading was here used to synthesize a cocrystal of probenecid, an uricosuric drug used in treating gout and hyperuricemia, with the…”
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13
I. Technological approaches to improve the dissolution behavior of nateglinide, a lipophilic insoluble drug: Nanoparticles and co-mixing
Published in International journal of pharmaceutics (15-09-2013)“…Dissolution profiles of nateglinide H samples of different particle size (NH=about 18μm, 2μm and 0.5μm), alone, compared to the same samples co-mixed with…”
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14
Improvement of the dissolution behavior of gliclazide, a slightly soluble drug, using solid dispersions
Published in Journal of drug delivery science and technology (01-04-2015)“…Gliclazide is a second generation sulphonylurea used in the treatment of type 2 diabetes characterized by a low risk of hypoglycaemia and cardiovascular…”
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15
Dosage variability of veterinary drug products, containing furosemide, linked to tablet splitting
Published in Open veterinary journal (Tripoli, Libya) (01-01-2021)“…Furosemide is a potent diuretic drug widely used to treat congestive heart failure in dogs and cats, but it shows remarkable variability in bioavailability and…”
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16
Hybrid Nanocomposites of Tenoxicam: Layered Double Hydroxides Inorganic Carriers
Published in Molecules (Basel, Switzerland) (01-05-2023)“…The search for effective systems to facilitate the release of poorly bioavailable drugs is a forefront topic for the pharmaceutical market. Materials…”
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17
A Perspective on the Use of Hydroxyapatites to Improve the Dissolution Behavior of Poorly Water-Soluble Piretanide
Published in Pharmaceutics (13-11-2024)“…Background/Objectives: Interest in drug delivery systems (DDS) based on inorganic substrates has increased in parallel with the increase in the number of…”
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18
Zaltoprofen-layered double hydroxide hybrids to enhance zaltoprofen solubility and dissolution rate
Published in Applied clay science (03-01-2023)“…The zaltoprofen-LDH hybrid was successfully synthesized by coprecipitation method, and its dissolution profile and solubility in different fluids, that…”
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19
Tableted hydrophilic electrospun nanofibers to promote meloxicam dissolution rate
Published in Journal of drug delivery science and technology (01-12-2021)“…This study investigated the ability of hydrophilic electrospun nanofibers to enhance the dissolution rate of poorly soluble drug Meloxicam (MLX). The drug was…”
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20
The peculiar dissolution behaviour of Piretanide hosted in layered double hydroxides
Published in Applied clay science (15-11-2020)“…Layered double hydroxides (LDHs) are widely used as inorganic hosts for different applications, in particular for drug delivery. Piretanide, a poorly soluble…”
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