Search Results - "Mager, Peter P"

Brain-derived neurotrophic factor controls functional differentiation and microcircuit formation of selectively isolated fast-spiking GABAergic interneurons by Berghuis, Paul, Dobszay, Marton B., Sousa, Kyle M., Schulte, Gunnar, Mager, Peter P., Härtig, Wolfgang, Görcs, Tamás J., Zilberter, Yuri, Ernfors, Patrik, Harkany, Tibor

“…GABAergic interneurons with high‐frequency firing, fast‐spiking (FS) cells, form synapses on perisomatic regions of principal cells in the neocortex and…”
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The active site of HIV-1 protease by Mager, Peter P.

“…The active site of the homodimeric HIV‐1 protease includes six amino acids (triads AspThrGly found in each monomer) in amino acid positions 25 to 27 and 25′ to…”
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Regulation of the pH sensitivity of human P2X₃ receptors by N-linked glycosylation by Wirkner, Kerstin, Stanchev, Doychin, Milius, Doreen, Hartmann, Lars, Kato, Erzsebet, Zadori, Zoltan S, Mager, Peter P, Rubini, Patrizia, Nörenberg, Wolfgang, Illes, Peter

“…The human (h) P2X₃ receptor and its mutants deficient in one out of four N-glycosylation sites were expressed in HEK293 cells. Concentration-response curves…”
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Conserved lysin and arginin residues in the extracellular loop of P2X3 receptors are involved in agonist binding by FISCHER, Wolfgang, ZADORI, Zoltan, KULLNICK, Yvonne, GROGER-ARNDT, Helke, FRANKE, Heike, WIRKNER, Kerstin, ILLES, Peter, MAGER, Peter P

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Conserved lysin and arginin residues in the extracellular loop of P2X(3) receptors are involved in agonist binding by Fischer, Wolfgang, Zadori, Zoltan, Kullnick, Yvonne, Gröger-Arndt, Helke, Franke, Heike, Wirkner, Kerstin, Illes, Peter, Mager, Peter P

“…Wild-type human (h) P2X(3) receptors expressed in HEK293 cells responded to the prototypic agonist alpha,beta-methylene ATP (alpha,beta-meATP) with rapidly…”
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Regulation of Human Recombinant P2X3 Receptors by Ecto-Protein Kinase C by Wirkner, Kerstin, Stanchev, Doychin, Koles, Laszlo, Klebingat, Markus, Dihazi, Hassan, Flehmig, Gesine, Vial, Catherine, Evans, Richard J, Furst, Susanna, Mager, Peter P, Eschrich, Klaus, Illes, Peter

“…The whole-cell patch-clamp technique was used to record current responses to nucleotides and nucleosides in human embryonic kidney HEK293 cells transfected…”
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Regulation of the pH sensitivity of human P2X receptors by N-linked glycosylation by Wirkner, Kerstin, Stanchev, Doychin, Milius, Doreen, Hartmann, Lars, Kato, Erzsebet, Zadori, Zoltan S, Mager, Peter P, Rubini, Patrizia, Nörenberg, Wolfgang, Illes, Peter

“…The human (h) P2X(3) receptor and its mutants deficient in one out of four N-glycosylation sites were expressed in HEK293 cells. Concentration-response curves…”
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Hybrid canonical-correlation neural-network approach applied to nonnucleoside HIV-1 reverse transcriptase inhibitors (HEPT derivatives) by Mager, Peter P

“…Beneficial antiviral HIV-1 chemotherapy is associated with adverse reactions. To optimize the desired actions and to lower the side effects of nonnucleoside…”
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Bridging the gap between structural bioinformatics and receptor research: the membrane-embedded, ligand-gated, P2X glycoprotein receptor by Mager, Peter P, Weber, Anje, Illes, Peter

“…No details on P2X receptor architecture had been known at the atomic resolution level. Using comparative homology-based molecular modelling and threading, it…”
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Pathological peptide folding in Alzheimer's disease and other conformational disorders by Mager, Peter P, Penke, Botond, Walter, Regina, Harkany, Tibor, Härtignny, Wolfgang

“…Main neuropathological hallmarks of Alzheimer's disease (AD) and other neurodegenerative disorders are the deposition of neurofibrillary tangles consisting of…”
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Quantitative structure-activity relationship analysis of the cation permeability of the P2X2 channel by Mager, Peter P, Weber, Anje, Illes, Peter

“…The membrane-embedded, ligand-gated P2X glycoprotein receptor is a monovalent-bivalent cation channel that is activated by physiological concentrations of…”
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A check on rational drug design: Molecular simulation of the allosteric inhibition of HIV-1 reverse transcriptase by Mager, Peter P.

“…First page of article…”
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The monomers of the P2X1 receptor model and KcsA protein share a similar structural fold by Mager, Peter P, Weber, Anje, Sanchez, Luis, Wirkner, Kerstin, Illes, Peter

“…There is evidence that the P2X1 receptor subunit is involved in apoptosis, platelet aggregation, and smooth muscle contraction. The conformation of the…”
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Structural bioinformatics and QSAR analysis applied to the acetylcholinesterase and bispyridinium aldoximes by Mager, Peter P, Weber, Anje

“…The methods of bioinformatics, molecular modelling, and quantitative structure-activity relationships (QSARs) using regression and artificial neural network…”
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Interactions of the dimeric triad of HIV-1 aspartyl protease with inhibitors by Mager, Peter P, De Clercq, Erik, Froeyen, Matheus, Reinhardt, Robert

“…Strong hydrogen-bonding forces between the Thr26 and Thr26' of the protease stabilize the internal cage of the dimeric triad of the aspartyl HIV-1 protease…”
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Regulation of the pH sensitivity of human P2X 3 receptors by N‐linked glycosylation by Wirkner, Kerstin, Stanchev, Doychin, Milius, Doreen, Hartmann, Lars, Kato, Erzsebet, Zadori, Zoltan S., Mager, Peter P., Rubini, Patrizia, Nörenberg, Wolfgang, Illes, Peter

“…Abstract The human (h) P2X 3 receptor and its mutants deficient in one out of four N‐glycosylation sites were expressed in HEK293 cells. Concentration–response…”
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Regulation of the pH sensitivity of human P2X sub(3) receptors by N-linked glycosylation by Wirkner, Kerstin, Stanchev, Doychin, Milius, Doreen, Hartmann, Lars, Kato, Erzsebet, Zadori, Zoltan S, Mager, Peter P, Rubini, Patrizia, Noerenberg, Wolfgang, Illes, Peter

“…The human (h) P2X sub(3) receptor and its mutants deficient in one out of four N-glycosylation sites were expressed in HEK293 cells. Concentration-response…”
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Molecular simulation of the primary and secondary structures of the Aβ(1-42)-peptide of Alzheimer's disease by Mager, Peter P.

“…The major protein constituent of the deposits of Alzheimer's disease is the so‐called amyloid β‐peptide (Aβ) which was derived from proteolysis of a large…”
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Conserved lysin and arginin residues in the extracellular loop of P2X 3 receptors are involved in agonist binding by Fischer, Wolfgang, Zadori, Zoltan, Kullnick, Yvonne, Gröger-Arndt, Helke, Franke, Heike, Wirkner, Kerstin, Illes, Peter, Mager, Peter P.

“…Wild-type human (h) P2X 3 receptors expressed in HEK293 cells responded to the prototypic agonist α,β-methylene ATP (α,β-meATP) with rapidly desensitizing…”
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Molecular simulation of the primary and secondary structures of the A(1-42)-peptide of Alzheimer's disease by Mager, Peter P

“…The major protein constituent of the deposits of Alzheimer's disease is the so-called amyloid -peptide (A) which was derived from proteolysis of a large…”
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