Search Results - "Magdeleyns, Elke"

Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease by Heuvel, Ellen G.H.M. van den, van Schoor, Natasja M, Lips, Paul, Magdeleyns, Elke J.P, Deeg, Dorly J.H, Vermeer, Cees, Heijer, Martin den

“…Abstract Objectives Vitamin K plays a pivotal role in the synthesis of Matrix Gla protein (MGP), a calcification inhibitor in vascular tissue. Vascular…”
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Circulating uncarboxylated matrix gla protein is associated with vitamin K nutritional status, but not coronary artery calcium, in older adults by Shea, M Kyla, O'Donnell, Christopher J, Vermeer, Cees, Magdeleyns, Elke J P, Crosier, Michael D, Gundberg, Caren M, Ordovas, José M, Kritchevsky, Stephen B, Booth, Sarah L

“…Matrix Gla protein (MGP) is a calcification inhibitor in vascular tissue that must be carboxylated by vitamin K to function. Evidence suggests circulating…”
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The Circulating Inactive Form of Matrix Gla Protein Is a Surrogate Marker for Vascular Calcification in Chronic Kidney Disease: A Preliminary Report by Schurgers, Leon J, Barreto, Daniela V, Barreto, Fellype C, Liabeuf, Sophie, Renard, Cedric, Magdeleyns, Elke J, Vermeer, Cees, Choukroun, Gabriel, Massy, Ziad A

“…Vitamin K-dependent matrix Gla protein (MGP) acts as a calcification inhibitor in vitro and in vivo. The present study was performed to (1) determine plasma…”
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Vitamin K intake and status are low in hemodialysis patients by Cranenburg, Ellen C M, Schurgers, Leon J, Uiterwijk, Herma H, Beulens, Joline W J, Dalmeijer, Gerdien W, Westerhuis, Ralf, Magdeleyns, Elke J, Herfs, Marjolein, Vermeer, Cees, Laverman, Gozewijn D

“…Vitamin K is essential for the activity of γ-carboxyglutamate (Gla)-proteins including matrix Gla28 protein and osteocalcin; an inhibitor of vascular…”
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Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species by Cranenburg, Ellen C M, Koos, Ralf, Schurgers, Leon J, Magdeleyns, Elke J, Schoonbrood, Thea H M, Landewé, Robert B, Brandenburg, Vincent M, Bekers, Otto, Vermeer, Cees

“…Matrix γ-carboxyglutamate (Gla) protein (MGP) is an important local inhibitor of vascular calcification, which can undergo two post-translational…”
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Circulating matrix Gla protein is associated with coronary artery calcification and vitamin K status in healthy women by Dalmeijer, Geertje W, van der Schouw, Yvonne T, Vermeer, Cees, Magdeleyns, Elke J, Schurgers, Leon J, Beulens, Joline W.J

“…Matrix Gla protein (MGP) is a vitamin K-dependent protein and an inhibitor of vascular calcification. Vitamin K is required for the carboxylation of MGP and…”
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Circulating Nonphosphorylated Carboxylated Matrix Gla Protein Predicts Survival in ESRD by SCHLIEPER, Georg, WESTENFELD, Ralf, DIMKOVIC, Nada, FLOEGE, Jürgen, SCHURGERS, Leon J, KRÜGER, Thilo, CRANENBURG, Ellen C, MAGDELEYNS, Elke J, BRANDENBURG, Vincent M, DJURIC, Zivka, DAMJANOVIC, Tatjana, KETTELER, Markus, VERMEER, Cees

“…The mechanisms for vascular calcification and its associated cardiovascular mortality in patients with ESRD are not completely understood. Dialysis patients…”
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Matrix Gla Protein Species and Risk of Cardiovascular Events in Type 2 Diabetic Patients by DALMEIJER, Geertje W, VAN DER SCHOUW, Yvonne T, MAGDELEYNS, Elke J, VERMEER, Cees, MONIQUE VERSCHUREN, W. M, BOER, Jolanda M. A, BEULENS, Joline W. J

“…To investigate the relationship of circulating matrix Gla protein (MGP) species with incident cardiovascular disease (CVD) or coronary heart disease (CHD) in…”
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Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects by Theuwissen, Elke, Cranenburg, Ellen C., Knapen, Marjo H., Magdeleyns, Elke J., Teunissen, Kirsten J., Schurgers, Leon J., Smit, Egbert, Vermeer, Cees

“…Vitamin K is required for the carboxylation of Gla-proteins in the liver (coagulation factors) and extra-hepatic tissues, such as bone (osteocalcin, OC), and…”
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Effects of storage‐induced platelet microparticles on the initiation and propagation phase of blood coagulation by Keuren, Jeffery F.W., Magdeleyns, Elke J.P., Govers‐Riemslag, José W.P., Lindhout, Theo, Curvers, Joyce

“…Summary Platelets shed microparticles, which support haemostasis via adherence to the damaged vasculature and by promoting blood coagulation. We investigated…”
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Circulating species of matrix Gla protein and the risk of vascular calcification in healthy women by Dalmeijer, Geertje W, van der Schouw, Yvonne T, Magdeleyns, Elke J, Vermeer, Cees, Elias, Sjoerd G, Velthuis, Birgitta K, de Jong, Pim A, Beulens, Joline W.J

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Factor Va, bound to microparticles released during platelet storage, is resistant to inactivation by activated protein C by Magdeleyns, Elke J.P., Keuren, Jeffrey F.W., Curvers, Joyce

“…BACKGROUND: Microparticles (MPs) support coagulation and can be helpful in restoring the hemostatic system in thrombocytopenic patients. The anticoagulant…”
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Effect of Vitamin K2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial by Westenfeld, Ralf, MD, Krueger, Thilo, MD, Schlieper, Georg, MD, Cranenburg, Ellen C.M., MD, PhD, Magdeleyns, Elke J., BSc, Heidenreich, Stephan, MD, Holzmann, Stefan, MD, Vermeer, Cees, PhD, Jahnen-Dechent, Willi, PhD, Ketteler, Markus, MD, Floege, Jürgen, MD, Schurgers, Leon J., PhD

“…Background Vascular calcification is a predictor of cardiovascular morbidity and mortality. Hemodialysis patients experience severe vascular calcifications…”
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Endogenous factor V synthesis in megakaryocytes contributes negligibly to the platelet factor V pool by Christella, M, Thomassen, LG, Castoldi, E, Tans, G, Magdeleyns, EJ, Delaunoit, C, Debusscher, L, Van Assche, KJ, Rosing, J

“…Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. BACKGROUND AND OBJECTIVES:…”
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Effect of Vitamin K 2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial by Westenfeld, Ralf, Krueger, Thilo, Schlieper, Georg, Cranenburg, Ellen C.M., Magdeleyns, Elke J., Heidenreich, Stephan, Holzmann, Stefan, Vermeer, Cees, Jahnen-Dechent, Willi, Ketteler, Markus, Floege, Jürgen, Schurgers, Leon J.

“…Vascular calcification is a predictor of cardiovascular morbidity and mortality. Hemodialysis patients experience severe vascular calcifications. Matrix Gla…”
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Impaired vitamin K recycling in uremia is rescued by vitamin K supplementation by Kaesler, Nadine, Magdeleyns, Elke, Herfs, Marjolein, Schettgen, Thomas, Brandenburg, Vincent, Fliser, Danilo, Vermeer, Cees, Floege, Jürgen, Schlieper, Georg, Krüger, Thilo

“…In chronic kidney disease, vitamin K-dependent proteins, including the calcification inhibitor matrix Gla protein, are largely uncarboxylated indicating that…”
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Vascular calcification in patients with type 2 diabetes: the involvement of matrix Gla protein by Liabeuf, Sophie, Bourron, Olivier, Olivier, Bourron, Vemeer, Cees, Theuwissen, Elke, Magdeleyns, Elke, Aubert, Carole Elodie, Brazier, Michel, Mentaverri, Romuald, Hartemann, Agnes, Massy, Ziad A

“…Matrix Gla protein (MGP) is an important inhibitor of calcification. The objective of the present study of patients with type 2 diabetes and normal or slightly…”
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Abstract P397: Circulating Species of Matrix Gla Protein and the Risk of Vascular Calcification in Healthy Women by Dalmeijer, Gerdien, van der Schouw, Yvonne, Magdeleyns, Elke, Vermeer, Cees, Velthuis, Birgitta, de Jong, Pim, Beulens, Joline

“…Abstract only Background: Matrix Gla protein (MGP) is an inhibitor of vascular calcification that requires vitamin K for its carboxylation. Circulating MGP…”
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Abstract P186: Circulating Desphospho-uncarboxylated Matrix Gla Protein and the Risk of Coronary Heart Disease and Stroke by Dalmeijer, Geertje W, van der Schouw, Yvonne T, Magdeleyns, Elke J, Vermeer, Cees, Verschuren, W. Monique M, Boer, Jolanda M, Beulens, Joline W

“…Abstract only Background: Matrix Gla protein (MGP) is a vitamin K dependent protein and a potent inhibitor of vascular calcification. Desphospho-uncarboxylated…”
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Abstract P071: The Effect of Menaquinone -7 Supplementation on Circulating Species of Matrix-Gla Protein by Dalmeijer, Gerdien W, van der Schouw, Yvonne T, Magdeleyns, Elke, Vermeer, Cees, Beulens, Joline W

“…Abstract only Background: Menaquinones intake is associated with a reduced risk of coronary calcification and coronary heart disease. This association may be…”
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