Search Results - "Maganti, Rama K"
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Best practice guide for the treatment of REM sleep behavior disorder (RBD)
Published in Journal of clinical sleep medicine (15-02-2010)“…Modifying the sleep environment is recommended for the treatment of patients with RBD who have sleep-related injury. Level A Clonazepam is suggested for the…”
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Ketogenic Diet Affects Sleep Architecture in C57BL/6J Wild Type and Fragile X Mice
Published in International journal of molecular sciences (22-09-2023)“…Nearly half of children with fragile X syndrome experience sleep problems including trouble falling asleep and frequent nighttime awakenings. The goals here…”
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Adult Inception of Ketogenic Diet Therapy Increases Sleep during the Dark Cycle in C57BL/6J Wild Type and Fragile X Mice
Published in International journal of molecular sciences (01-06-2024)“…Sleep problems are a significant phenotype in children with fragile X syndrome. Our prior work assessed sleep-wake cycles in male mice and wild type (WT)…”
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Best practice guide for the treatment of nightmare disorder in adults
Published in Journal of clinical sleep medicine (15-08-2010)“…Prazosin is recommended for treatment of Posttraumatic Stress Disorder (PTSD)-associated nightmares. Level A. Image Rehearsal Therapy (IRT) is recommended for…”
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A predictive epilepsy index based on probabilistic classification of interictal spike waveforms
Published in PloS one (06-11-2018)“…Quantification of interictal spikes in EEG may provide insight on epilepsy disease burden, but manual quantification of spikes is time-consuming and subject to…”
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Sleep‐wake characteristics in a mouse model of severe traumatic brain injury: Relation to posttraumatic epilepsy
Published in Epilepsia open (01-03-2021)“…Study objectives Traumatic brain injury (TBI) results in sequelae that include posttraumatic epilepsy (PTE) and sleep‐wake disturbances. Here, we sought to…”
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Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1‐null mice
Published in Epilepsia (Copenhagen) (01-09-2009)“…Summary Introduction: Seizures are known to perturb circadian rhythms in humans as well as in animal models of epilepsy. However, it is unknown whether…”
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Neurotoxic effects associated with antibiotic use: management considerations
Published in British journal of clinical pharmacology (01-09-2011)“…The clinical manifestations of antibiotic‐induced neurotoxic effects, the underlying mechanisms and management strategies have been reviewed. PubMed and OVID…”
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Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy
Published in Epilepsia (Copenhagen) (01-08-2018)“…Objectives Circadian rhythms are affected in many neurological disorders. Although sleep disturbances are known in epilepsy, data on circadian rhythm…”
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Sleep Deprivation Exacerbates Seizures and Diminishes GABAergic Tonic Inhibition
Published in Annals of neurology (01-11-2021)“…Patients with epilepsy report that sleep deprivation is a common trigger for breakthrough seizures. The basic mechanism of this phenomenon is unknown. In the…”
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Plasma exchange in cryptogenic new onset refractory status epilepticus
Published in Seizure (London, England) (01-01-2013)“…Abstract Objective New onset refractory status epilepticus (NORSE) is a recently described entity and has been difficult to treat because the etiology is often…”
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Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy
Published in The Journal of neuroscience (17-11-2021)“…In temporal lobe epilepsy, the ability of the dentate gyrus to limit excitatory cortical input to the hippocampus breaks down, leading to seizures. The dentate…”
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Untangling a Web: Basic Mechanisms of the Complex Interactions Between Sleep, Circadian Rhythms, and Epilepsy
Published in Epilepsy Currents (01-03-2021)“…Seizures have sleep–wake and circadian patterns in various epilepsies and, in turn, disrupt sleep and circadian rhythms. The resultant sleep deprivation (SD)…”
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Dual orexin antagonist normalized sleep homeostatic drive, enhanced GABAergic inhibition, and suppressed seizures after traumatic brain injury
Published in Sleep (New York, N.Y.) (12-12-2022)“…Abstract Study Objectives Traumatic brain injury (TBI) can result in posttraumatic epilepsy (PTE) and sleep disturbances. We hypothesized that treatment with…”
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Sleep and diurnal rest-activity rhythm disturbances in a mouse model of Alzheimer’s disease
Published in Sleep (New York, N.Y.) (01-11-2020)“…Abstract Study Objectives Accumulating evidence suggests a strong association between sleep, amyloid-beta (Aβ) deposition, and Alzheimer’s disease (AD). We…”
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Histone deacetylase inhibitors restore normal hippocampal synaptic plasticity and seizure threshold in a mouse model of Tuberous Sclerosis Complex
Published in Scientific reports (27-03-2019)“…Abnormal synaptic plasticity has been implicated in several neurological disorders including epilepsy, dementia and Autism Spectrum Disorder (ASD). Tuberous…”
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An automated, machine learning–based detection algorithm for spike‐wave discharges (SWDs) in a mouse model of absence epilepsy
Published in Epilepsia open (01-03-2019)“…Summary Objective Manual detection of spike‐wave discharges (SWDs) from electroencephalography (EEG) records is time intensive, costly, and subject to…”
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EEG and Epilepsy Monitoring
Published in Continuum (Minneapolis, Minn.) (01-06-2013)“…Purpose of ReviewThis article reviews the utility of EEG and prolonged video-EEG telemetry in the diagnosis and management of a patient with epilepsy.Recent…”
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Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP
Published in Epilepsy currents (01-05-2021)“…Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Likely pathophysiological mechanisms include…”
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Interobserver Agreement in the Interpretation of EEG Patterns in Critically Ill Adults
Published in Journal of clinical neurophysiology (01-10-2008)Get full text
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