Search Results - "Magalhães Saraiva, Roberto"
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Addressing challenges and advancing treatment strategies for Chagas cardiomyopathy
Published in The Lancet (British edition) (07-09-2024)“…While aetiological treatment is not recommended for patients with advanced chronic Chagas cardiomyopathy after the BENEFIT trial showed no significant…”
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Effect of Physical Exercise Training in Patients With Chagas Heart Disease (from the PEACH STUDY)
Published in The American journal of cardiology (01-05-2020)“…•Exercise training improved functional capacity in Chagas heart disease.•Exercisers tolerate higher loads of exercise after 3- and 6 months of…”
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Inspiratory muscle endurance is similarly reduced in the early and late stages of chronic Chagas heart disease
Published in Tropical medicine & international health (01-05-2024)“…Inspiratory muscle strength (IMS) appears to be reduced in subjects with chronic Chagas heart disease (CHD), especially in the presence of heart failure (HF)…”
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Effect of an exercise-based cardiac rehabilitation program on quality of life of patients with chronic Chagas cardiomyopathy: results from the PEACH randomized clinical trial
Published in Scientific reports (08-04-2024)“…To investigate the effect of an exercise-based cardiac rehabilitation program on the quality of life (QoL) of patients with chronic Chagas cardiomyopathy…”
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Association between Trypanosoma cruzi DTU TcII and chronic Chagas disease clinical presentation and outcome in an urban cohort in Brazil
Published in PloS one (02-12-2020)“…The specific roles of parasite characteristics and immunological factors of the host in Chagas disease progression and prognosis are still under debate…”
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Indeterminate form of Chagas disease: historical, conceptual, clinical, and prognostic aspects
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2021)“…Chagas disease (CD) remains a serious endemic disease in Latin America and a major public health problem. Because of globalization, the disease has spread to…”
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Ageing with Chagas disease: an overview of an urban Brazilian cohort in Rio de Janeiro
Published in Parasites & vectors (19-06-2018)“…Chagas disease control programmes have decreased the prevalence of Chagas disease in Latin America. Together with migration to urban areas and increase in life…”
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Exploring the Historical Background and Clinical Implications of Electrocardiogram in the Context of Chagas Disease Research
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2023)“…Chagas disease (CD) remains one of the most significant endemic diseases in Latin America. Approximately 30% of individuals with CD develop the cardiac form,…”
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A clinical adverse drug reaction prediction model for patients with chagas disease treated with benznidazole
Published in Antimicrobial agents and chemotherapy (01-11-2014)“…Benznidazole (BZN) is the main trypanocidal drug used to treat Chagas disease, and the evidence supporting the benefits of BZN use during the chronic phase of…”
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The repositioned drugs disulfiram/diethyldithiocarbamate combined to benznidazole: Searching for Chagas disease selective therapy, preventing toxicity and drug resistance
Published in Frontiers in cellular and infection microbiology (29-07-2022)“…Chagas disease (CD) affects at least 6 million people in 21 South American countries besides several thousand in other nations all over the world. It is…”
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Analysis of Three-Dimensional Scar Architecture and Conducting Channels by High-Resolution Contrast-Enhanced Cardiac Magnetic Resonance Imaging in Chagas Heart Disease
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2022)“…BACKGROUNDWe aimed to describe the morphology of the border zone of viable myocardium surrounded by scarring in patients with Chagas heart disease and study…”
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Inspiratory Muscle Strength in Chagas Cardiomyopathy: A Systematic Scoping Review
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2023)“…The increase in inflammatory markers associated with persistent chronic fibrosing myocarditis, a characteristic of chronic Chagas disease, can result in a…”
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Chagas disease mortality during the coronavirus disease 2019 pandemic: A Brazilian referral center experience
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2022)“…We investigated the mortality rates of patients with Chagas disease (CD) during the coronavirus disease 2019 (COVID-19) pandemic and assessed the association…”
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Factors related to the discontinuation and mortality rates of a cardiac rehabilitation programme in patients with Chagas disease: a 6‐year experience in a Brazilian tertiary centre
Published in Tropical medicine & international health (01-03-2021)“…Objectives To describe the clinical and sociodemographic characteristics of participants as well as discontinuation and mortality rates in a cardiac…”
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Chagas heart disease is associated with decreased physical activity levels: A cross-sectional analysis
Published in International journal of cardiology. Heart & vasculature (01-06-2024)“…Studies evaluating physical activity (PA) levels in individuals with Chagas disease (CD) are still scarce. The present study aimed to evaluate PA levels in CD…”
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Adverse drug events and the associated factors in patients with chronic Chagas disease
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…Herein, we aimed to identify the factors associated with adverse drug events (ADEs) in chronic Chagas disease (CD) patients. We analyzed 320 medical notes from…”
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Discussing the Score of Cardioembolic Ischemic Stroke in Chagas Disease
Published in Tropical medicine and infectious disease (26-05-2020)“…Chagas disease is an important infection in Latin America but it is also reported in non-endemic countries all over the world. Around 30% of infected patients…”
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TGF-β Polymorphisms Are a Risk Factor for Chagas Disease
Published in Disease markers (01-01-2018)“…Transforming growth factor β1 (TGF-β1) is an important mediator in Chagas disease. Furthermore, patients with higher TGF-β1 serum levels show a worse clinical…”
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Agreement between upper endoscopy and esophagography in the diagnosis of megaesophagus in Chagas disease
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2019)“…The diagnosis and classification of megaesophagus can be challenging in patients with Chagas disease. The present study aimed to evaluate the agreement between…”
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FIRST REPORT OF ACUTE CHAGAS DISEASE BY VECTOR TRANSMISSION IN RIO DE JANEIRO STATE, BRAZIL
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-07-2015)“…Chagas disease (CD) is an endemic anthropozoonosis from Latin America of which the main means of transmission is the contact of skin lesions or mucosa with the…”
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