Search Results - "Magalhães, Silvia Maria Meira"
-
1
Myelodysplastic syndrome patients present more severe respiratory muscle impairment and reduced forced vital capacity: Is disordered inflammatory signaling the culprit?
Published in PloS one (06-09-2017)“…The ageing process is associated with gradual decline in respiratory system performance. Anemia is highly prevalent among older adults and usually associated…”
Get full text
Journal Article -
2
Do small increases in serum ferritin impact prognosis in lower-risk MDS patients?
Published in International journal of hematology (01-05-2020)Get full text
Journal Article -
3
Myelodysplastic Syndrome Over Time: A Comparative Analysis of Overall Outcome
Published in Mayo Clinic proceedings (01-12-2019)Get full text
Journal Article -
4
The role of adiposity, adipokines and polymorphisms of leptin and adiponectin in myelodysplastic syndromes
Published in British journal of nutrition (14-03-2024)“…The aim of the present study was to investigate the relationship between leptin and adiponectin gene polymorphisms, circulating levels of leptin and…”
Get full text
Journal Article -
5
Tissue methylation and demethylation influence translesion synthesis DNA polymerases (TLS) contributing to the genesis of chromosomal abnormalities in myelodysplastic syndrome
Published in Journal of clinical pathology (01-02-2022)“…DNA methylation has its distribution influenced by DNA demethylation processes with the catalytic conversion of 5-methylcytosine (5mC) into…”
Get more information
Journal Article -
6
ERVs-TLR3-IRF axis is linked to myelodysplastic syndrome pathogenesis
Published in Medical oncology (Northwood, London, England) (01-03-2021)“…Toll-like receptors are mutated or overexpressed in up to 50% of patients with myelodysplastic syndrome (MDS). Endogenous retroviruses (ERV) trigger TLR3…”
Get full text
Journal Article -
7
-
8
Interleukin-8 and nuclear factor kappa B are increased and positively correlated in myelodysplastic syndrome
Published in Medical oncology (Northwood, London, England) (01-10-2017)“…The pathogenesis of myelodysplastic syndromes (MDS) is complex and depends on the interaction between aberrant hematopoietic cells and their microenvironment,…”
Get full text
Journal Article -
9
Erdheim-Chester disease after Essential Thrombocythemia: coincidence or not?
Published in Hematology, Transfusion and Cell Therapy (01-01-2023)Get full text
Journal Article -
10
Can synthetic lethality approach be used with DNA repair genes for primary and secondary MDS?
Published in Medical oncology (Northwood, London, England) (01-12-2019)“…Cancer-specific defects in DNA repair pathways create the opportunity to employ synthetic lethality approach. Recently, GEMA (gene expression and mutation…”
Get full text
Journal Article -
11
Functional polymorphisms of DNA repair genes in Latin America reinforces the heterogeneity of Myelodysplastic Syndrome
Published in Hematology, Transfusion and Cell Therapy (01-04-2023)“…Nucleotide excision repair pathway (NER) is an essential mechanism for single-strand breaks (SSB) repair while xeroderma pigmentosum family (XPA to XPG) is the…”
Get full text
Journal Article -
12
Dysregulation of interferon regulatory genes reinforces the concept of chronic immune response in myelodysplastic syndrome pathogenesis
Published in Hematological oncology (01-10-2019)Get full text
Journal Article -
13
Influence of Functional Polymorphisms in DNA repair genes of Myelodysplastic Syndrome
Published in Leukemia research (01-09-2016)“…Graphical abstract…”
Get full text
Journal Article -
14
Polymorphisms of DNA repair genes are related to the pathogenesis of myelodysplastic syndrome
Published in Hematological oncology (01-12-2015)“…Some studies show that alterations in DNA repair genes polymorphisms are associated with the pathogenesis and susceptibility of Myelodysplastic Syndrome (MDS)…”
Get full text
Journal Article -
15
HFE gene mutation and oxidative damage biomarkers in patients with myelodysplastic syndromes and its relation to transfusional iron overload: an observational cross-sectional study
Published in BMJ open (03-04-2015)“…Objective A relation between transfusional IOL (iron overload), HFE status and oxidative damage was evaluated. Design, setting and participants An…”
Get full text
Journal Article -
16
Aurora-B expression may not contribute to disease progression: a reflection of the heterogeneous pathogenesis?
Published in Haematologica (Roma) (01-10-2012)Get full text
Journal Article -
17
Role of the STING pathway in myeloid neoplasms: a prospero-registered systematic review of principal hurdles of STING on the road to the clinical practice
Published in Medical oncology (Northwood, London, England) (24-04-2024)“…Myeloid neoplasms are a group of bone marrow diseases distinguished by disruptions in the molecular pathways that regulate the balance between hematopoietic…”
Get full text
Journal Article -
18
Plasma IL-33 levels are decreased in patients with high-risk myelodysplastic syndrome and show no correlation with pro-inflammatory IL-6 levels
Published in Cytokine (Philadelphia, Pa.) (01-12-2021)“…•The role of abnormal IL-33 expression in MDS remains widely unknown.•Lower levels of IL-33 were found in MDS group when compared to healthy…”
Get full text
Journal Article -
19
Metabolic syndrome: A patient-related prognostic factor for cancer?
Published in Journal of cancer research and therapeutics (01-10-2022)Get full text
Journal Article -
20
It is not just the number of metaphases that matters
Published in Leukemia research (01-05-2018)Get full text
Journal Article