Search Results - "Magafa, Vassiliki"

Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice by Ishiguro, Susumu, Yoshimura, Kiyoshi, Tsunedomi, Ryouichi, Oka, Masaaki, Takao, Sonshin, Inui, Makoto, Kawabata, Atsushi, Wall, Terrahn, Magafa, Vassiliki, Cordopatis, Paul, Tzakos, Andreas G, Tamura, Masaaki

“…We have recently discovered the potential involvement of angiotensin II type 2 receptor (AT2R) signaling in pancreatic cancer using AT2R deficient mice. To…”
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Beneficial Effects of Sideritis clandestina Extracts and Sideridiol against Amyloid β Toxicity by Gioran, Anna, Paikopoulos, Yiorgos, Panagiotidou, Eleni, Rizou, Aikaterini E I, Nasi, Georgia I, Dimaki, Virginia D, Vraila, Konstantina D, Bezantakou, Dimitra S, Spatharas, Panagiotis M, Papandreou, Nikos C, Magafa, Vassiliki, Lamari, Fotini N, Iconomidou, Vassiliki A, Chondrogianni, Niki

“…Alzheimer's disease (AD) is the most common form of dementia. Given the link between oxidative stress and AD, many studies focus on the identification of…”
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The thyroxine-containing thyroglobulin peptide (aa 2549-2560) is a target epitope in iodide-accelerated spontaneous autoimmune thyroiditis by Kolypetri, Panayota, Carayanniotis, Karen, Rahman, Shofiur, Georghiou, Paris E, Magafa, Vassiliki, Cordopatis, Paul, Carayanniotis, George

“…Enhanced iodide ingestion is known to accelerate the incidence and severity of spontaneous autoimmune thyroiditis [iodide-accelerated spontaneous autoimmune…”
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Arabidopsis thaliana Plant Natriuretic Peptide Active Domain Forms Amyloid-like Fibrils in a pH-Dependent Manner by Nasi, Georgia I, Aktypi, Foteini D, Spatharas, Panagiotis M, Louros, Nikolaos N, Tsiolaki, Paraskevi L, Magafa, Vassiliki, Trougakos, Ioannis P, Iconomidou, Vassiliki A

“…Plant natriuretic peptides (PNPs) are hormones that have been extracted from many different species, with the PNP (AtPNP-A) being the most studied among them…”
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Electronic Sculpting of Ligand-GPCR Subtype Selectivity: The Case of Angiotensin II by Magnani, Francesca, Pappas, Charalampos G, Crook, Tim, Magafa, Vassiliki, Cordopatis, Paul, Ishiguro, Susumu, Ohta, Naomi, Selent, Jana, Bosnyak, Sanja, Jones, Emma S, Gerothanassis, Ioannis P, Tamura, Masaaki, Widdop, Robert E, Tzakos, Andreas G

“…GPCR subtypes possess distinct functional and pharmacological profiles, and thus development of subtype-selective ligands has immense therapeutic potential…”
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Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin by Koutsioumpa, Marina, Drosou, Georgia, Mikelis, Constantinos, Theochari, Katerina, Vourtsis, Dionussios, Katsoris, Panagiotis, Giannopoulou, Efstathia, Courty, Jose, Petrou, Christos, Magafa, Vassiliki, Cordopatis, Paul, Papadimitriou, Evangelia

“…Pleiotrophin (PTN) is a heparin-binding growth factor with significant role(s) in tumour growth and angiogenesis. Although implication of endogenous PTN has…”
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Gonadotropin-releasing Hormone Analogues Alter Gene Expression of Metalloproteinases and their Tissue Inhibitors in Human Breast Cancer Epithelial Cells by LAMARI, Fotini N, ZOMPRA, Aikaterini A, PATERAKI, Evangelia, KOUSIDOU, Olga Ch, MAGAFA, Vassiliki, KARAMANOS, Nikos K, CORDOPATIS, Paul

“…Luteinizing hormone-releasing hormone (LHRH or GnRH) is not only produced by hypothalamus, but also by other normal and cancer tissues. GnRH peptide agonists…”
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Synthesis and Biological Evaluation of New CRH Analogues by Papazacharias, Spyridon, Magafa, Vassiliki, Bernad, Nicole, Pairas, George, Spyroulias, Georgios A., Martinez, Jean, Cordopatis, Paul

“…A series of 7 new human/rat Corticotropin Releasing Hormone (h/r-CRH) analogues were synthesized. The induced alterations include substitution of Phe at…”
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Synthesis and Biological Evaluation of New GnRH Analogues on Pituitary and Breast Cancer Cells by Zompra, Aikaterini A, Magafa, Vassiliki, Chryssanthi, Dimitra G, Lamari, Fotini N, Spyroulias, Georgios A, Maina, Theodosia, Nock, Berthold A, Karamanos, Nikos K, Cordopatis, Paul

“…GnRH analogues have been extensively used in oncology to induce reversible chemical castration due to their hypophysiotropic action. In addition to that, it…”
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αCGRP, another amyloidogenic member of the CGRP family by Tsiolaki, Paraskevi L., Nasi, Georgia I., Baltoumas, Fotis A., Louros, Nikolaos N., Magafa, Vassiliki, Hamodrakas, Stavros J., Iconomidou, Vassiliki A.

“…The Calcitonin-gene related peptide (CGRP) family is a group of peptide hormones, which consists of IAPP, calcitonin, adrenomedullin, intermedin, αCGRP and…”
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Novel stable analogues of the neurotensin C-terminal hexapeptide containing unnatural amino acids by Magafa, Vassiliki, Matsoukas, Minos-Timotheos, Karageorgos, Vlasios, Dermitzaki, Eirini, Exarchakou, Revekka, Stylos, Evgenios Κ., Pardalos, Michail, Margioris, Andrew N., Varvounis, George, Tzakos, Andreas G., Spyroulias, Georgios A., Liapakis, George

“…Neurotensin (NT) (pGlu–Leu–Tyr–Glu–Asn–Lys–Pro–Arg–Arg–Pro–Tyr–Ile–Leu) exerts a dual function as a neurotransmitter/neuromodulator in the central nervous…”
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Beneficial Effects of ISideritis clandestina/I Extracts and Sideridiol against Amyloid β Toxicity by Gioran, Anna, Paikopoulos, Yiorgos, Panagiotidou, Eleni, Rizou, Aikaterini E. I, Nasi, Georgia I, Dimaki, Virginia D, Vraila, Konstantina D, Bezantakou, Dimitra S, Spatharas, Panagiotis M, Papandreou, Nikos C, Magafa, Vassiliki, Lamari, Fotini N, Iconomidou, Vassiliki A, Chondrogianni, Niki

“…Alzheimer’s disease (AD) is the most common form of dementia. Given the link between oxidative stress and AD, many studies focus on the identification of…”
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Structural studies and cytotoxicity assays of "aggregation-prone" IAPP(8-16) and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin by Louros, Nikolaos N, Tsiolaki, Paraskevi L, Zompra, Aikaterini A, Pappa, Eleni V, Magafa, Vassiliki, Pairas, George, Cordopatis, Paul, Cheimonidou, Christina, Trougakos, Ioannis P, Iconomidou, Vassiliki A, Hamodrakas, Stavros J

“…Amyloid deposits to the islets of Langerhans are responsible for the gradual loss of pancreatic β-cells leading to type II diabetes mellitus. Human mature…”
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Structural studies and cytotoxicity assays of "aggregation-prone" IAPP8-16 and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin by Louros, Nikolaos N., Tsiolaki, Paraskevi L., Zompra, Aikaterini A., Pappa, Eleni V., Magafa, Vassiliki, Pairas, George, Cordopatis, Paul, Cheimonidou, Christina, Trougakos, Ioannis P., Iconomidou, Vassiliki A., Hamodrakas, Stavros J.

“…ABSTRACT Amyloid deposits to the islets of Langerhans are responsible for the gradual loss of pancreatic β‐cells leading to type II diabetes mellitus. Human…”
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Comparison of the solution structures of angiotensin I & II by Spyroulias, Georgios A., Nikolakopoulou, Panagiota, Tzakos, Andreas, Gerothanassis, Ioannis P., Magafa, Vassiliki, Manessi‐Zoupa, Evy, Cordopatis, Paul

“…Conformational analysis of angiotensin I (AI) and II (AII) peptides has been performed through 2D 1H‐NMR spectroscopy in dimethylsulfoxide and…”
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Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production by Valero, Thairy Reyes, Sturchler, Emmanuel, Jafferjee, Malika, Rengo, Giuseppe, Magafa, Vassiliki, Cordopatis, Paul, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios

“…The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion induction, a steroid hormone that contributes to the pathology of…”
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Structural studies and cytotoxicity assays of “aggregation‐prone” IAPP 8–16 and its non‐amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin by Louros, Nikolaos N., Tsiolaki, Paraskevi L., Zompra, Aikaterini A., Pappa, Eleni V., Magafa, Vassiliki, Pairas, George, Cordopatis, Paul, Cheimonidou, Christina, Trougakos, Ioannis P., Iconomidou, Vassiliki A., Hamodrakas, Stavros J.

“…ABSTRACT Amyloid deposits to the islets of Langerhans are responsible for the gradual loss of pancreatic β‐cells leading to type II diabetes mellitus. Human…”
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Synthesis and biological activity of oxytocin analogues containing unnatural amino acids in position 9: structure activity study by Magafa, Vassiliki, Borovičková, Lenka, Slaninová, Jiřina, Cordopatis, Paul

“…We report the solid phase synthesis and some pharmacological properties of 24 oxytocin (OT) analogues. Basic modifications at position 9 (introduction of l- or…”
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Synthesis and biological activity of oxytocin analogues containing conformationally-restricted residues in position 7 by Fragiadaki, Maria, Magafa, Vassiliki, Borovicková, Lenka, Slaninová, Jiřina, Cordopatis, Paul

“…We report the solid-phase synthesis and some pharmacological properties of twenty oxytocin (OT) analogues. Basic modifications at position 7 (introduction of…”
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In position 7 l- and d-Tic-substituted oxytocin and deamino oxytocin: NMR study and conformational insights by Spyranti, Zinovia, Fragiadaki, Maria, Magafa, Vassiliki, Borovickova, Lenka, Spyroulias, Georgios A, Cordopatis, Paul, Slaninova, Jirina

“…Incorporation of l- or d-Tic into position 7 of oxytocin (OT) and its deamino analogue ([Mpa¹]OT) resulted in four analogues, [l-Tic⁷]OT (1), [d-Tic⁷]OT (2),…”
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