Search Results - "Maegawa, Rodrigo"
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A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation
Published in Blood (11-06-2020)“…Programmed cell death-1 (PD-1)/programmed death ligand-1 blockade may potentially augment graft-vs-tumor effects following allogeneic hematopoietic cell…”
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Therapy for patients with chronic phase-chronic myeloid leukemia previously treated with ⩾2 tyrosine kinase inhibitors: a systematic literature review
Published in Therapeutic Advances in Hematology (01-01-2023)“…Background: ATP-competitive tyrosine kinase inhibitors (TKIs) are the current standard of care for patients with chronic phase-chronic myeloid leukemia…”
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Molecular response in newly diagnosed chronic-phase chronic myeloid leukemia: prediction modeling and pathway analysis
Published in Haematologica (Roma) (01-06-2023)“…Tyrosine kinase inhibitor therapy revolutionized chronic myeloid leukemia treatment and showed how targeted therapy and molecular monitoring could be used to…”
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Chronic Myeloid Leukemia: Part II-Cost of Care Among Patients in Advanced Phases or Later Lines of Therapy in Chronic Phase in the United States from a Commercial Perspective
Published in Journal of health economics and outcomes research (Online) (04-08-2022)“…Tyrosine kinase inhibitors (TKIs) are the standard-of-care treatment for chronic myeloid leukemia in chronic phase (CML-CP). Despite advances in therapy, there…”
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Chronic Myeloid Leukemia: Part I-Real-World Treatment Patterns, Healthcare Resource Utilization, and Associated Costs in Later Lines of Therapy in the United States
Published in Journal of health economics and outcomes research (Online) (04-08-2022)“…Despite advances in tyrosine kinase inhibitor (TKI) therapy for chronic myeloid leukemia in chronic phase (CML-CP), a sizeable proportion of patients with…”
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Triple-Negative Breast Cancer: Unique Biology and Its Management
Published in Cancer investigation (01-09-2010)“…Triple-negative breast cancer is defined by the lack of expression of estrogen-receptor, progesterone-receptor, and HER-2/neu. It primarily, but not…”
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A Phase I/Ib Study of Nivolumab for Relapsed Hematologic Malignancies after Allogeneic Hematopoietic Cell Transplantation (alloHCT)
Published in Blood (29-11-2018)“…Patients (pts) with relapsed hematologic malignancies (HM) after alloHCT are a unique population, given the potential to harness a dormant graft-vs.-tumor…”
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Four new mutations in the BCHE gene of human butyrylcholinesterase in a Brazilian blood donor sample
Published in Molecular genetics and metabolism (01-04-2005)“…The genetic variation of human butyrylcholinesterase has been associated with height, body mass index, Alzheimer’s disease, and response to xenobiotic agents…”
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Targeted Literature Review of Patient Reported Outcomes (PROs) in Chronic Myeloid Leukemia (CML) Patients Receiving Second and Later Lines of Treatment
Published in Blood (05-11-2020)“…Background: Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic CML in the last several years; however, the failure rates associated…”
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Clinical Characteristics and Late-Line Treatment Patterns of Patients with Chronic Myeloid Leukemia Who Received 2 Prior Lines of Tyrosine Kinase Inhibitor Therapy in US Community Oncology Practices
Published in Blood (23-11-2021)“…BACKGROUND: Current treatment guidelines recommend tyrosine kinase inhibitors (TKIs) as first-line and second-line treatment options for patients with chronic…”
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Ibrutinib Efficacy Across Subgroups of Patients With High-Risk Chronic Lymphocytic Leukemia: A Systematic Literature Review
Published in Clinical lymphoma, myeloma and leukemia (01-09-2024)Get full text
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CLL-481 Ibrutinib Efficacy Across Subgroups of Patients With High-Risk Chronic Lymphocytic Leukemia: A Systematic Literature Review
Published in Clinical lymphoma, myeloma and leukemia (01-09-2024)“…Ibrutinib is a first-in-class, once-daily covalent Bruton tyrosine kinase (BTK) inhibitor approved for the treatment of patients with chronic lymphocytic…”
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Real-World Treatment Patterns, Healthcare Resource Utilization and Associated Costs Among Patients with Chronic Myeloid Leukemia in Later Lines of Therapy
Published in Blood (05-11-2020)“…Introduction: Despite advances in tyrosine kinase inhibitor (TKI) therapy for chronic myeloid leukemia (CML), there remains a sizeable proportion of patients…”
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Real-World Usage of Asciminib in Patients with Chronic Myeloid Leukemia (CML) in Chronic Phase (CP) in the United States (US) Using a Large Claims Database
Published in Blood (15-11-2022)Get full text
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Effectiveness of Second-Line (2L) Tyrosine Kinase Inhibitor (TKI) Therapy after Resistance or Intolerance to a Prior TKI in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase (Ph+ CML-CP)
Published in Blood (05-11-2020)“…Introduction: Second-generation (2G) TKIs have shown better efficacy than first-generation (1G) TKI in patients (pts) with Ph+ CML-CP. However, real-world…”
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Trial in Progress: Asciminib in Monotherapy 4 CML (AIM4CML), a Phase IIIb Study of Asciminib Monotherapy in Patients with Chronic Myeloid Leukemia in Chronic Phase without or with T315I Mutations
Published in Blood (23-11-2021)“…Chronic myeloid leukemia (CML) is driven by the constitutively active BCR-ABL1 tyrosine kinase. Several adenosine triphosphate (ATP)-competitive tyrosine…”
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