Search Results - "Maeda, Yusuke T."
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1
Negative autoregulation controls size scaling in confined gene expression reactions
Published in Scientific reports (22-06-2022)“…Gene expression via transcription-translation is the most fundamental reaction to sustain biological systems, and complex reactions occur in a small…”
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2
Development of an artificial cell, from self-organization to computation and self-reproduction
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-2011)“…This article describes the state and the development of an artificial cell project. We discuss the experimental constraints to synthesize the most elementary…”
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3
Edge current and pairing order transition in chiral bacterial vortices
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2021)“…Bacterial suspensions show turbulence-like spatiotemporal dynamics and vortices moving irregularly inside the suspensions. Understanding these ordered vortices…”
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4
Phase Separation and Protein Partitioning in Compartmentalized Cell-Free Expression Reactions
Published in Biomacromolecules (09-08-2021)“…Liquid–liquid phase separation (LLPS) is important to control a wide range of reactions from gene expression to protein degradation in a cell-sized space. To…”
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Anomalous Scaling of Gene Expression in Confined Cell-Free Reactions
Published in Scientific reports (09-05-2018)“…Cellular surface breaks the symmetry of molecular diffusion across membrane. Here, we study how steric interactions between the surface and the bulk of…”
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6
Geometry-driven collective ordering of bacterial vortices
Published in Soft matter (2017)“…Controlling the phases of matter is a challenge that spans from condensed materials to biological systems. Here, by imposing a geometric boundary condition, we…”
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7
Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle
Published in Developmental cell (22-04-2019)“…The microtubule-based spindle is subjected to various mechanical forces during cell division. How the structure generates and responds to forces while…”
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8
Effects of long DNA folding and small RNA stem–loop in thermophoresis
Published in Proceedings of the National Academy of Sciences - PNAS (30-10-2012)“…In thermophoresis, with the fluid at rest, suspensions move along a gradient of temperature. In an aqueous solution, a PEG polymer suspension is depleted from…”
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9
Thermal separation: interplay between the Soret effect and entropic force gradient
Published in Physical review letters (11-07-2011)“…Thermophoresis, the Soret effect, depletes a high concentration of a polyethylene glycol polymer solution from the hot region and builds a concentration…”
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10
Controlling Collective Motion of Kinesin-Driven Microtubules via Patterning of Topographic Landscapes
Published in Nano letters (22-12-2021)“…Biomolecular motor proteins that generate forces by consuming chemical energy obtained from ATP hydrolysis play pivotal roles in organizing cytoskeletal…”
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11
Insights into the Micromechanical Properties of the Metaphase Spindle
Published in Cell (24-06-2011)“…The microtubule-based metaphase spindle is subjected to forces that act in diverse orientations and over a wide range of timescales. Currently, we cannot…”
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12
Tug-of-war between actomyosin-driven antagonistic forces determines the positioning symmetry in cell-sized confinement
Published in Nature communications (15-06-2020)“…Symmetric or asymmetric positioning of intracellular structures including the nucleus and mitotic spindle steers various biological processes such as cell…”
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13
Morphological growth dynamics, mechanical stability, and active microtubule mechanics underlying spindle self-organization
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-2022)“…The spindle is a dynamic intracellular structure self-organized from microtubules and microtubule-associated proteins. The spindle's bipolar morphology is…”
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14
Protein Needles Designed to Self‐Assemble through Needle Tip Engineering
Published in Small (Weinheim an der Bergstrasse, Germany) (01-03-2022)“…The dynamic process of formation of protein assemblies is essential to form highly ordered structures in biological systems. Advances in structural and…”
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15
Collective motion of epithelial cells along a wrinkled 3D-buckled hydrogel
Published in RSC advances (06-07-2022)“…Epithelial cells migrate autonomously by aligning and inducing a collective motion. Controlling the collective motion of epithelial cells in geometrically…”
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16
Unveiling the physics underlying symmetry breaking of the actin cytoskeleton: An artificial cell-based approach
Published in Biophysics and Physicobiology (01-01-2023)“…Single-cell behaviors cover many biological functions, such as cell division during morphogenesis and tissue metastasis, and cell migration during cancer cell…”
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17
Exploring order in active turbulence: Geometric rule and pairing order transition in confined bacterial vortices
Published in Biophysics and Physicobiology (01-01-2022)“…Ordered collective motion emerges in a group of autonomously motile elements (known as active matter) as their density increases. Microswimmers, such as…”
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18
Opto-thermal diffusiophoresis of soft biological matter: from physical principle to molecular manipulation
Published in Biophysical reviews (01-04-2020)“…Transport of ions and molecules under external field gradients is fundamental phenomena relevant to many biological systems including molecular motors in…”
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19
Ordered patterns of cell shape and orientational correlation during spontaneous cell migration
Published in PloS one (17-11-2008)“…In the absence of stimuli, most motile eukaryotic cells move by spontaneously coordinating cell deformation with cell movement in the absence of stimuli. Yet…”
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Directing and Boosting of Cell Migration by the Entropic Force Gradient in Polymer Solution
Published in Langmuir (24-11-2015)“…Noncontact manipulation of nano/micromaterials presents a great challenge in fields ranging from biotechnology to nanotechnology. In this study we developed a…”
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