Search Results - "Maeda, Akio"

Phase 2 study of arsenic trioxide followed by autologous hematopoietic cell transplantation for relapsed acute promyelocytic leukemia by Yanada, Masamitsu, Tsuzuki, Motohiro, Fujita, Hiroyuki, Fujimaki, Katsumichi, Fujisawa, Shin, Sunami, Kazutaka, Taniwaki, Masafumi, Ohwada, Akira, Tsuboi, Kosuke, Maeda, Akio, Takeshita, Akihiro, Ohtake, Shigeki, Miyazaki, Yasushi, Atsuta, Yoshiko, Kobayashi, Yukio, Naoe, Tomoki, Emi, Nobuhiko

“…The optimal treatments for relapsed acute promyelocytic leukemia (APL) remain equivocal. We conducted a phase 2 study to evaluate the efficacy and feasibility…”
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Outcomes after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia harboring t(7;11)(p15;p15) by Harada, Kaito, Doki, Noriko, Aoki, Jun, Mori, Jinichi, Machida, Shinichiro, Masuko, Masayoshi, Uchida, Naoyuki, Najima, Yuho, Fukuda, Takahiro, Kanamori, Heiwa, Ogawa, Hiroyasu, Ota, Shuichi, Ogawa, Kazuei, Takahashi, Satoshi, Kasai, Masanobu, Maeda, Akio, Nagafuji, Koji, Kawakita, Toshiro, Ichinohe, Tatsuo, Atsuta, Yoshiko

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Bortezomib-based strategy with autologous stem cell transplantation for newly diagnosed multiple myeloma: a phase II study by the Japan Study Group for Cell Therapy and Transplantation (JSCT-MM12) by Sunami, Kazutaka, Matsumoto, Morio, Fuchida, Shin-ichi, Omoto, Eijiro, Takamatsu, Hiroyuki, Adachi, Yoko, Choi, Ilsong, Fujishima, Naohito, Kiguchi, Toru, Miyamoto, Toshihiro, Maeda, Akio, Suzumiya, Junji, Yamamura, Ryosuke, Nagafuji, Koji, Nakazato, Tomonori, Kuroda, Yoshiaki, Yujiri, Toshiaki, Takamatsu, Yasushi, Harada, Mine, Akashi, Koichi

“…Background The Japan Study Group for Cell Therapy and Transplantation (JSCT) organized a phase II study to evaluate the efficacy and safety of a treatment…”
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Development of a technique for the investigation of folding dynamics of single proteins for extended time periods by Kinoshita, Masahito, Kamagata, Kiyoto, Maeda, Akio, Goto, Yuji, Komatsuzaki, Tamiki, Takahashi, Satoshi

“…A technique was developed for the detection of fluorescence signals from free single molecules for extended time periods and was applied to the…”
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Dehydration of main-chain amides in the final folding step of single-chain monellin revealed by time-resolved infrared spectroscopy by Kimura, Tetsunari, Maeda, Akio, Nishiguchi, Shingo, Ishimori, Koichiro, Morishima, Isao, Konno, Takashi, Goto, Yuji, Takahashi, Satoshi

“…Kinetic IR spectroscopy was used to reveal β-sheet formation and water expulsion in the folding of single-chain monellin (SMN) composed of a five-stranded…”
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Structure Changes upon Deprotonation of the Proton Release Group in the Bacteriorhodopsin Photocycle by Morgan, Joel E., Vakkasoglu, Ahmet S., Lanyi, Janos K., Lugtenburg, Johan, Gennis, Robert B., Maeda, Akio

“…In the photocycle of bacteriorhodopsin at pH 7, a proton is ejected to the extracellular medium during the protonation of Asp-85 upon formation of the M…”
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Identification of Tau and MAP2 as novel substrates of Rho‐kinase and myosin phosphatase by Amano, Mutsuki, Kaneko, Takako, Maeda, Akio, Nakayama, Masanori, Ito, Masaaki, Yamauchi, Takashi, Goto, Hideyuki, Fukata, Yuko, Oshiro, Noriko, Shinohara, Azusa, Iwamatsu, Akihiro, Kaibuchi, Kozo

“…Rho‐kinase and myosin phosphatase are implicated in the phosphorylation‐state of myosin light chain downstream of Rho, which is thought to induce smooth muscle…”
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Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 Exoenzyme in the Rho-Guanine Nucleotide Dissociation Inhibitor-1 Complex by Genth, Harald, Gerhard, Ralf, Maeda, Akio, Amano, Mutsuki, Kaibuchi, Kozo, Aktories, Klaus, Just, Ingo

“…RhoA, -B, and -C are ADP-ribosylated by Clostridium botulinum exoenzyme C3 to induce redistribution of the actin filaments in intact cells, a finding that has…”
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A Role for Internal Water Molecules in Proton Affinity Changes in the Schiff Base and Asp85 for One-way Proton Transfer in Bacteriorhodopsin by Morgan, Joel E., Gennis, Robert B., Maeda, Akio

“…Light‐induced proton pumping in bacteriorhodospin is carried out through five proton transfer steps. We propose that the proton transfer to Asp85 from the…”
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Systemic mastocytosis with refractory ascites successfully treated with interferon-α and a leukotriene receptor antagonist by Mizuno, Ishikazu, Tominaga, Ryo, Gomyo, Hiroshi, Maeda, Akio, Kajimoto, Kazuyoshi, Yonezawa, Kenji, Shinzato, Isaku, Murayama, Tohru

“…A 67-year-old male was referred to our hospital because of anemia, thrombocytopenia, and massive ascites. A diagnosis of systemic mastocytosis was made based…”
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Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho‐kinase by Kaneko, Takako, Maeda, Akio, Takefuji, Mikito, Aoyama, Hiroki, Nakayama, Masanori, Kawabata, Saeko, Kawano, Yoji, Iwamatsu, Akihiro, Amano, Mutsuki, Kaibuchi, Kozo

“…After binding of epidermal growth factor (EGF), the EGF receptor is activated, internalized by endocytosis, and subsequently degraded in the lysosomal pathway…”
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Proton transfer mechanism in bacteriorhodopsin--FTIR spectroscopy and internal water molecules by Maeda, Akio

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Glutamic Acid 204 is the Terminal Proton Release Group at the Extracellular Surface of Bacteriorhodopsin () by Brown, Leonid S., Sasaki, Jun, Kandori, Hideki, Maeda, Akio, Needleman, Richard, Lanyi, Janos K.

“…We have measured proton release into the medium after proton transfer from the retinal Schiff base to Asp85 in the photocycle and the C=O stretch bands of…”
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Identification of Calponin as a Novel Substrate of Rho-Kinase by Kaneko, Takako, Amano, Mutsuki, Maeda, Akio, Goto, Hideyuki, Takahashi, Katsuhito, Ito, Masaaki, Kaibuchi, Kozo

“…Calponin, an F-actin-associated protein implicated in the regulation of smooth muscle contraction, is known to be phosphorylated in vitro by protein kinase C…”
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Water Structural Changes in the L and M Photocycle Intermediates of Bacteriorhodopsin as Revealed by Time-Resolved Step-Scan Fourier Transform Infrared (FTIR) Spectroscopy by Morgan, Joel E, Vakkasoglu, Ahmet S, Gennis, Robert B, Maeda, Akio

“…In previous Fourier transform infrared (FTIR) studies of the photocycle intermediates of bacteriorhodopsin at cryogenic temperatures, water molecules were…”
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Cone Beam Computed Tomography-Based Anatomical Assessment of the Olfactory Fossa by Lopes, Sérgio Lúcio Pereira de Castro, Maeda, Fernando Akio, Martinelli, Thiago, Ogawa, Celso Massahiro, Gonçalves, Bianca Costa, Paixão, Aline Kataki, Costa, André Luiz Ferreira, Trivino, Tarcila

“…This study aimed to investigate the olfactory fossa according to the Keros classification using cone beam computed tomography. This cross-sectional study…”
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Ca2+‐independent phospholipase A2‐dependent sustained Rho‐kinase activation exhibits all‐or‐none response by Maeda, Akio, Ozaki, Yu‐ichi, Sivakumaran, Sudhir, Akiyama, Tetsuro, Urakubo, Hidetoshi, Usami, Ayako, Sato, Miharu, Kaibuchi, Kozo, Kuroda, Shinya

“…Sustained contraction of cells depends on sustained Rho‐associated kinase (Rho‐kinase) activation. We developed a computational model of the Rho‐kinase pathway…”
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Protein Structural Changes in Bacteriorhodopsin upon Photoisomerization As Revealed by Polarized FTIR Spectroscopy by Kandori, Hideki, Kinoshita, Norimichi, Shichida, Yoshinori, Maeda, Akio

“…We used polarized Fourier transform infrared (FTIR) spectroscopy to investigate the structural change of bacteriorhodopsin (BR) upon photoisomerization of the…”
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FTIR Spectroscopy Reveals Microscopic Structural Changes of the Protein around the Rhodopsin Chromophore upon Photoisomerization by Kandori, Hideki, Maeda, Akio

“…Fourier transform infrared spectroscopy was used to investigate the local structure around the chromophore of rhodopsin and its change upon photoisomerization…”
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Relocation of Water Molecules between the Schiff Base and the Thr46−Asp96 Region during Light-Driven Unidirectional Proton Transport by Bacteriorhodopsin:  An FTIR Study of the N Intermediate by Maeda, Akio, Gennis, Robert B, Balashov, Sergei P, Ebrey, Thomas G

“…A key event in light-driven proton pumping by bacteriorhodopsin is the formation of the L intermediate, whose transition to M is accompanied by the first…”
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