Relative nerve blocking properties of bupivacaine and ropivacaine in dogs undergoing brachial plexus block using a nerve stimulator

In the present study, the efficacy of a nerve stimulator in performing brachial plexus block (BPB) in dogs was investigated. The nerve blocking effects of bupivacaine and ropivacaine for BPB were also compared. Twelve beagles were allocated to groups based on the following treatments: conventional B...

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Bibliographic Details
Published in:	Journal of Veterinary Medical Science Vol. 71; no. 10; pp. 1279 - 1284
Main Authors:	Sakonju, I., Kitasato Univ., Towada, Aomori (Japan). School of Veterinary Medicine, Maeda, K, Maekawa, R, Maebashi, R, Kakuta, T, Takase, K
Format:	Journal Article
Language:	English
Published:	Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01-10-2009 Japan Science and Technology Agency
Subjects:	Amides - pharmacology ANAESTHETICS ANESTESICOS ANESTHESIQUE Anesthetics, Local - pharmacology Animals Brachial Plexus - physiology brachial plexus block bupivacaine Bupivacaine - pharmacology canine CHIEN DOGS Dose-Response Relationship, Drug ESTIMULO Female FRECUENCIA CARDIACA FREQUENCE CARDIAQUE HEART RATE http://www.fao.org/aos/agrovoc#c_13669 http://www.fao.org/aos/agrovoc#c_2352 http://www.fao.org/aos/agrovoc#c_36749 http://www.fao.org/aos/agrovoc#c_381 http://www.fao.org/aos/agrovoc#c_5137 http://www.fao.org/aos/agrovoc#c_5149 http://www.fao.org/aos/agrovoc#c_7415 Male MEDICAMENT NEUROTROPE MEDICAMENTOS NEUROTROPICOS NERF Nerve Block - veterinary nerve stimulator NERVES NERVIOS NEUROTROPIC DRUGS Pain Threshold - drug effects PERRO RESPIRATION RATE Ropivacaine STIMULI STIMULUS TASA DE RESPIRACION TAUX DE RESPIRATION
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Summary:	In the present study, the efficacy of a nerve stimulator in performing brachial plexus block (BPB) in dogs was investigated. The nerve blocking effects of bupivacaine and ropivacaine for BPB were also compared. Twelve beagles were allocated to groups based on the following treatments: conventional BPB with 0.5% bupivacaine (0.5% BupiM group) or BPB with 0.5% bupivacaine, 0.5% ropivacaine or 0.75% ropivacaine and a nerve stimulator (the 0.5% BupiS, 0.5% RopiS and 0.75% RopiS groups, respectively). After BPB, nerve blocking effects were assessed based on sensory blockade in several cutaneous areas and knuckling. The ratio of full block (blockade in all cutaneous areas) for 0.5% BupiM was 25%, and that for 0.5% BupiS was significantly higher, 75% (p0.05). For the 0.5% BupiS, 0.5% RopiS and 0.75% RopiS groups, the average duration of full block was 387, 184 and 275 min, respectively, and the average duration of knuckling was 703, 460 and 421 min, respectively. The duration of full block and knuckling for the two ropivacaine groups was shorter compared with that of the 0.5% BupiS group. In conclusion, when using bupivacaine and ropivacaine for BPB in dogs, it is worth noting that there are differences in onset time and duration and that effective perioperative analgesia can be achieved depending on the intended use.
Bibliography:	L70 2010000461 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0916-7250 1347-7439
DOI:	10.1292/jvms.001279